id: gomodel:66c7d41500002687
title: "mitotic cytokinesis, division site positioning\n (GO:1902408) (G2)"
taxon: NCBITaxon:4896
status: production
date_modified: '2026-03-12'
comments:
- ' Duc1 binds PM PI(4,5)P2 at ER-PM contacts where it promotes proper Its3 PM distribution,
  promotes PM PI(4,5)P2 synthesis, and therefore contributes to proper CR-PM anchoring.

  '
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      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-02-14'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-14'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:66c7d41500002687/66c7d41500002727
- id: gomodel:66c7d41500002687/696022cd00001113
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-01-13'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPAC57A10.02
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0004674
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000314
      reference: PMID:15454577
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-01-13'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-01-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0031097
  part_of:
    type: BiologicalProcessAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-01-13'
      provided_by:
      - http://www.pombase.org
    term: GO:1902408
  happens_during:
    type: PhaseAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-01-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0051329
  causal_associations:
  - type: CausalAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-01-27'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002629
    downstream_activity: gomodel:66c7d41500002687/66c7d41500002727
molecules:
- id: gomodel:66c7d41500002687/66c7d41500002713
  term: CHEBI:18348
objects:
- id: PomBase:SPCC594.01
  label: duc1 Spom
  type: gocam:Object
- id: GO:0007009
  label: plasma membrane organization
  type: gocam:Object
- id: GO:0016308
  label: 1-phosphatidylinositol-4-phosphate 5-kinase activity
  type: gocam:Object
- id: PomBase:SPAC19G12.14
  label: its3 Spom
  type: gocam:Object
- id: GO:0046854
  label: phosphatidylinositol phosphate biosynthetic process
  type: gocam:Object
- id: GO:0016328
  label: lateral plasma membrane
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:18348
  label: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
  type: gocam:Object
- id: GO:0140550
  label: phosphatidylinositol-4,5-bisphosphate sensor activity
  type: gocam:Object
- id: PomBase:SPCPB16A4.02c
  label: opy1 Spom
  type: gocam:Object
- id: GO:0000281
  label: mitotic cytokinesis
  type: gocam:Object
- id: GO:0032153
  label: cell division site
  type: gocam:Object
- id: ECO:0000269
  label: experimental evidence used in manual assertion
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: GO:0005546
  label: phosphatidylinositol-4,5-bisphosphate binding
  type: gocam:Object
- id: PomBase:SPCC4B3.15
  label: mid1 Spom
  type: gocam:Object
- id: GO:1902408
  label: mitotic cytokinesis, division site positioning
  type: gocam:Object
- id: GO:0031097
  label: medial cortex
  type: gocam:Object
- id: GO:0051329
  label: mitotic interphase
  type: gocam:Object
- id: GO:0000087
  label: mitotic M phase
  type: gocam:Object
- id: GO:0004674
  label: protein serine/threonine kinase activity
  type: gocam:Object
- id: PomBase:SPAC57A10.02
  label: cdr2 Spom
  type: gocam:Object
- id: GO:0000085
  label: mitotic G2 phase
  type: gocam:Object
- id: GO:0005515
  label: protein binding
  type: gocam:Object
- id: PomBase:SPAC12B10.10
  label: nod1 Spom
  type: gocam:Object
- id: GO:0071341
  label: medial cortical node
  type: gocam:Object
- id: ECO:0000353
  label: physical interaction evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000316
  label: genetic interaction evidence used in manual assertion
  type: gocam:Object
- id: GO:0005085
  label: guanyl-nucleotide exchange factor activity
  type: gocam:Object
- id: PomBase:SPAC31A2.16
  label: gef2 Spom
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0000-0001-6330-7526
  date: '2026-03-12'
  provided_by:
  - http://www.pombase.org
