id: gomodel:6796b94c00000009
title: phosphatidylserine biosynthetic process (GO:0006659), phosphatidylethanolamine
  biosynthetic process (GO:0006646) and phosphatidylcholine biosynthetic process (GO:0006656)
taxon: NCBITaxon:4896
status: production
date_modified: '2026-03-12'
comments:
- Ale1 ? ADDED
activities:
- id: gomodel:6796b94c00000009/69a0c46f00004255
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000501
      reference: GO_REF:0000002
      with_objects:
      - InterPro:IPR004468
      - InterPro:IPR017456
      - InterPro:IPR033828
      provenances:
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        date: '2026-03-12'
        provided_by:
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    - term: ECO:0000318
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      with_objects:
      - PANTHER:PTN000167473
      - FB:FBgn0266452
      - SGD:S000003864
      - UniProtKB:P17812
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      - UniProtKB:P0A7E5
      - UniProtKB:Q4GZ95
      provenances:
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      date: '2026-03-12'
      provided_by:
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    term: PomBase:SPAC10F6.03c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0003883
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000266
      reference: GO_REF:0000024
      with_objects:
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      provenances:
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        date: '2026-03-12'
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    provenances:
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      date: '2026-03-12'
      provided_by:
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    term: GO:0005829
  part_of:
    type: BiologicalProcessAssociation
    evidence:
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      reference: GO_REF:0000002
      with_objects:
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      provenances:
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        date: '2026-03-12'
        provided_by:
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    - term: ECO:0000318
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      with_objects:
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      provenances:
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        date: '2026-03-12'
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      date: '2026-03-12'
      provided_by:
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    term: GO:0006241
  molecular_associations:
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    evidence:
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      reference: GO_REF:0000033
      with_objects:
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      provenances:
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    provenances:
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      date: '2026-03-12'
      provided_by:
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    predicate: RO:0002234
    molecule: gomodel:6796b94c00000009/69a0c46f00004245
  - type: MoleculeAssociation
    evidence:
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      reference: GO_REF:0000002
      with_objects:
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      provenances:
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        date: '2026-03-12'
        provided_by:
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    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
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      provenances:
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      with_objects:
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      provenances:
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  - type: MoleculeAssociation
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      provenances:
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        date: '2026-03-12'
        provided_by:
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    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
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- id: gomodel:6796b94c00000009/6796b94c00000142
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      date: '2025-01-27'
      provided_by:
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    term: PomBase:SPAC22A12.10
  molecular_function:
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    term: GO:0004307
  occurs_in:
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    evidence:
    - term: ECO:0000305
      reference: GO_REF:0000036
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      date: '2025-07-16'
      provided_by:
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    term: GO:0005789
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      provided_by:
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    term: GO:0006646
  molecular_associations:
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    term: PomBase:SPAC806.07
  molecular_function:
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    term: GO:0004550
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    evidence:
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      reference: PMID:16823372
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      with_objects:
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    term: GO:0005768
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        provided_by:
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    - term: ECO:0000315
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    term: GO:0006646
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    predicate: RO:0002233
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    term: PomBase:SPAC13G7.12c
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    term: GO:0005829
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    term: GO:0006656
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    predicate: RO:0002233
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    - term: ECO:0000318
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    term: PomBase:SPBC3D6.05
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    term: GO:0005789
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    - term: ECO:0000318
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    term: GO:0006654
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    term: PomBase:SPAC22A12.10
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    term: GO:0005635
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    term: GO:0005768
objects:
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  label: 1,2-diacyl-sn-glycerol 3-phosphate(2-)
  type: gocam:Object
- id: GO:0004605
  label: phosphatidate cytidylyltransferase activity
  type: gocam:Object
- id: PomBase:SPBC13A2.03
  label: bbl1 Spom
  type: gocam:Object
- id: GO:0016024
  label: CDP-diacylglycerol biosynthetic process
  type: gocam:Object
- id: GO:0005789
  label: endoplasmic reticulum membrane
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000269
  label: experimental evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:58332
  label: CDP-diacylglycerol(2-)
  type: gocam:Object
- id: GO:0003882
  label: CDP-diacylglycerol-serine O-phosphatidyltransferase activity
  type: gocam:Object
- id: PomBase:SPCC1442.12
  label: pps1 Spom
  type: gocam:Object
- id: GO:0006659
  label: phosphatidylserine biosynthetic process
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:57262
  label: 3-sn-phosphatidyl-L-serine(1-)
  type: gocam:Object
- id: GO:0004609
  label: phosphatidylserine decarboxylase activity
  type: gocam:Object
- id: PomBase:SPBC16E9.18
  label: psd1 Spom
  type: gocam:Object
- id: GO:0006646
  label: phosphatidylethanolamine biosynthetic process
  type: gocam:Object
- id: ECO:0000316
  label: genetic interaction evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPAC25B8.03
  label: psd2 Spom
  type: gocam:Object
- id: PomBase:SPAC31G5.15
  label: psd3 Spom
  type: gocam:Object
- id: CHEBI:64612
  label: 1,2-diacyl-sn-glycero-3-phosphoethanolamine zwitterion
  type: gocam:Object
- id: GO:0004608
  label: phosphatidylethanolamine N-methyltransferase activity
  type: gocam:Object
- id: PomBase:SPBC26H8.03
  label: cho2 Spom
  type: gocam:Object
- id: GO:0006656
  label: phosphatidylcholine biosynthetic process
  type: gocam:Object
- id: GO:0000773
  label: phosphatidyl-N-methylethanolamine N-methyltransferase activity
  type: gocam:Object
- id: PomBase:SPBC337.16
  label: cho1 Spom
  type: gocam:Object
- id: CHEBI:57643
  label: 1,2-diacyl-sn-glycero-3-phosphocholine
  type: gocam:Object
- id: GO:0004142
  label: diacylglycerol cholinephosphotransferase activity
  type: gocam:Object
- id: PomBase:SPAC22A12.10
  label: ept1 Spom
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:58779
  label: CDP-choline(1-)
  type: gocam:Object
- id: CHEBI:17815
  label: 1,2-diacyl-sn-glycerol
  type: gocam:Object
- id: GO:0004105
  label: choline-phosphate cytidylyltransferase activity
  type: gocam:Object
- id: PomBase:SPCC1827.02c
  label: pcy1 Spom
  type: gocam:Object
- id: GO:0006657
  label: CDP-choline pathway
  type: gocam:Object
- id: GO:0004103
  label: choline kinase activity
  type: gocam:Object
- id: PomBase:SPAC13G7.12c
  label: eki1 Spom
  type: gocam:Object
- id: CHEBI:15354
  label: choline
  type: gocam:Object
- id: GO:0004307
  label: ethanolaminephosphotransferase activity
  type: gocam:Object
- id: CHEBI:57876
  label: CDP-ethanolamine(1-)
  type: gocam:Object
- id: GO:0004306
  label: ethanolamine-phosphate cytidylyltransferase activity
  type: gocam:Object
- id: PomBase:SPAC15E1.05c
  label: ect1 Spom
  type: gocam:Object
- id: GO:0004305
  label: ethanolamine kinase activity
  type: gocam:Object
- id: CHEBI:57603
  label: ethanolaminium(1+)
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: CHEBI:33384
  label: L-serine zwitterion
  type: gocam:Object
- id: GO:0005783
  label: endoplasmic reticulum
  type: gocam:Object
- id: CHEBI:59789
  label: S-adenosyl-L-methionine zwitterion
  type: gocam:Object
- id: CHEBI:57856
  label: S-adenosyl-L-homocysteine zwitterion
  type: gocam:Object
- id: GO:0005635
  label: nuclear envelope
  type: gocam:Object
- id: GO:0031966
  label: mitochondrial membrane
  type: gocam:Object
- id: GO:0005743
  label: mitochondrial inner membrane
  type: gocam:Object
- id: ECO:0000250
  label: sequence similarity evidence used in manual assertion
  type: gocam:Object
- id: GO:0005768
  label: endosome
  type: gocam:Object
- id: GO:0003841
  label: 1-acylglycerol-3-phosphate O-acyltransferase activity
  type: gocam:Object
- id: PomBase:SPBC16A3.10
  label: ale1 Spom
  type: gocam:Object
- id: GO:0046474
  label: glycerophospholipid biosynthetic process
  type: gocam:Object
- id: CHEBI:57287
  label: coenzyme A(4-)
  type: gocam:Object
- id: CHEBI:57970
  label: 1-acyl-sn-glycerol 3-phosphate(2-)
  type: gocam:Object
- id: CHEBI:58342
  label: acyl-CoA(4-)
  type: gocam:Object
- id: CHEBI:58168
  label: 1-O-acyl-sn-glycero-3-phosphocholine
  type: gocam:Object
- id: GO:0047184
  label: 1-acylglycerophosphocholine O-acyltransferase activity
  type: gocam:Object
- id: GO:0106262
  label: 1-acylglycerophosphoethanolamine O-acyltransferase activity
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: CHEBI:64381
  label: 1-acyl-sn-glycero-3-phosphoethanolamine zwitterion
  type: gocam:Object
- id: GO:1990050
  label: phosphatidic acid transfer activity
  type: gocam:Object
- id: GO:0032865
  label: ERMES complex
  type: gocam:Object
- id: PomBase:SPBC27B12.01c
  label: mmm1 Spom
  type: gocam:Object
- id: PomBase:SPBC28F2.06c
  label: mdm12 Spom
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  label: gem1 Spom
  type: gocam:Object
- id: PomBase:SPAC17H9.17c
  label: mdm10 Spom
  type: gocam:Object
- id: PomBase:SPBC19C2.11c
  label: mdm34 Spom
  type: gocam:Object
- id: GO:0120010
  label: intermembrane phospholipid transfer
  type: gocam:Object
- id: GO:0044233
  label: mitochondria-associated endoplasmic reticulum membrane contact site
  type: gocam:Object
- id: GO:0017128
  label: phospholipid scramblase activity
  type: gocam:Object
- id: PomBase:SPAC343.06c
  label: pls1 Spom
  type: gocam:Object
- id: GO:0007006
  label: mitochondrial membrane organization
  type: gocam:Object
- id: GO:0005739
  label: mitochondrion
  type: gocam:Object
- id: ECO:0000303
  label: author statement without traceable support used in manual assertion
  type: gocam:Object
- id: GO:0004143
  label: ATP-dependent diacylglycerol kinase activity
  type: gocam:Object
- id: PomBase:SPBC3D6.05
  label: ptp4 Spom
  type: gocam:Object
- id: GO:0006654
  label: phosphatidic acid biosynthetic process
  type: gocam:Object
- id: GO:0004630
  label: D-type glycerophospholipase activity
  type: gocam:Object
- id: PomBase:SPAC2F7.16c
  label: pld1 Spom
  type: gocam:Object
- id: CHEBI:37563
  label: CTP(4-)
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- id: GO:0003883
  label: CTP synthase activity
  type: gocam:Object
- id: PomBase:SPAC10F6.03c
  label: cts1 Spom
  type: gocam:Object
- id: GO:0006241
  label: CTP biosynthetic process
  type: gocam:Object
- id: CHEBI:456216
  label: ADP(3-)
  type: gocam:Object
- id: GO:0004550
  label: nucleoside diphosphate kinase activity
  type: gocam:Object
- id: PomBase:SPAC806.07
  label: ndk1 Spom
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0009-0003-9059-1333
  date: '2026-03-12'
  provided_by:
  - http://www.pombase.org
