id: gomodel:67f85f2b00001360
title: proteasome assembly (GO:0043248)
taxon: NCBITaxon:4896
status: production
date_modified: '2026-03-19'
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        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    term: GO:0043248
  molecular_associations:
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:67f85f2b00001360/67f85f2b00001712
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67f85f2b00001360/67f85f2b00001361
  - type: CausalAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67f85f2b00001360/67f85f2b00001361
- id: gomodel:67f85f2b00001360/67f85f2b00001728
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPAC6C3.08
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0044183
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0007005
      reference: PMID:16823372
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000304
      reference: PMID:28765280
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    term: GO:0070682
  molecular_associations:
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:67f85f2b00001360/67f85f2b00001735
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
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        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
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      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67f85f2b00001360/67f85f2b00001378
  - type: CausalAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
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      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67f85f2b00001360/67f85f2b00001378
- id: gomodel:67f85f2b00001360/67f85f2b00001378
  enabled_by:
    type: EnabledByProteinComplexAssociation
    evidence:
    - term: ECO:0000305
      reference: GO_REF:0000111
      with_objects:
      - GO:0008540
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-19'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-19'
      provided_by:
      - http://www.pombase.org
    term: GO:0008540
    members:
    - type: ProteinComplexMemberAssociation
      evidence: []
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-16'
        provided_by:
        - http://www.pombase.org
      term: PomBase:SPCC1682.16
    - type: ProteinComplexMemberAssociation
      evidence: []
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-16'
        provided_by:
        - http://www.pombase.org
      term: PomBase:SPBC17D11.07c
    - type: ProteinComplexMemberAssociation
      evidence: []
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-16'
        provided_by:
        - http://www.pombase.org
      term: PomBase:SPBC16C6.07c
    - type: ProteinComplexMemberAssociation
      evidence: []
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-16'
        provided_by:
        - http://www.pombase.org
      term: PomBase:SPAC3A11.12c
    - type: ProteinComplexMemberAssociation
      evidence: []
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-16'
        provided_by:
        - http://www.pombase.org
      term: PomBase:SPBC4.07c
    - type: ProteinComplexMemberAssociation
      evidence: []
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-16'
        provided_by:
        - http://www.pombase.org
      term: PomBase:SPBC23G7.12c
    - type: ProteinComplexMemberAssociation
      evidence: []
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-16'
        provided_by:
        - http://www.pombase.org
      term: PomBase:SPBP19A11.03c
    - type: ProteinComplexMemberAssociation
      evidence: []
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-16'
        provided_by:
        - http://www.pombase.org
      term: PomBase:SPCC576.10c
    - type: ProteinComplexMemberAssociation
      evidence: []
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-16'
        provided_by:
        - http://www.pombase.org
      term: PomBase:SPAC637.10c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0036402
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000305
      reference: GO_REF:0000111
      with_objects:
      - GO:0008540
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-19'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-19'
      provided_by:
      - http://www.pombase.org
    term: GO:0043161
  causal_associations:
  - type: CausalAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-16'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002629
    downstream_activity: gomodel:67f85f2b00001360/67f85f2b00001361
- id: gomodel:67f85f2b00001360/67f85f2b00001718
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000303
      reference: GO_REF:0000051
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPAC2H10.02c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0044183
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0007005
      reference: PMID:16823372
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000291528
      - SGD:S000001269
      - UniProtKB:O00233
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    term: GO:0070682
  molecular_associations:
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000244
      reference: 'PMID: 19446322'
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-06-15'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-06-15'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:67f85f2b00001360/684b6c8100000447
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000250
      reference: 'PMID: 19446322'
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-06-15'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-06-15'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:67f85f2b00001360/67f85f2b00001725
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000307
      reference: GO_REF:0000015
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000307
      reference: GO_REF:0000015
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67f85f2b00001360/67f85f2b00001378
  - type: CausalAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67f85f2b00001360/67f85f2b00001378
- id: gomodel:67f85f2b00001360/67f85f2b00001689
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000307
      reference: GO_REF:0000015
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPCC14G10.03c
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0044183
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0007005
      reference: PMID:16823372
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000318
      reference: GO_REF:0000033
      with_objects:
      - PANTHER:PTN000302763
      - UniProtKB:Q9Y244
      - SGD:S000000377
      - TAIR:locus:2019599
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    term: GO:0043248
  molecular_associations:
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:67f85f2b00001360/67f85f2b00001696
  causal_associations:
  - type: CausalAssociation
    evidence:
    - term: ECO:0000307
      reference: GO_REF:0000015
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    - term: ECO:0000307
      reference: GO_REF:0000015
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2025-04-17'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67f85f2b00001360/67f85f2b00001361
  - type: CausalAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2025-04-17'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0012009
    downstream_activity: gomodel:67f85f2b00001360/67f85f2b00001361
molecules:
- id: gomodel:67f85f2b00001360/67f85f2b00001772
  term: PomBase:SPBC582.07c
- id: gomodel:67f85f2b00001360/67f85f2b00001735
  term: PomBase:SPCC576.10c
- id: gomodel:67f85f2b00001360/67f85f2b00001696
  term: PomBase:SPAC4A8.13c
- id: gomodel:67f85f2b00001360/684b6c8100000447
  term: PomBase:SPCC1682.16
- id: gomodel:67f85f2b00001360/67f85f2b00001712
  term: PomBase:SPAC6G10.04c
- id: gomodel:67f85f2b00001360/67f85f2b00001713
  term: PomBase:SPAC6G10.04c
- id: gomodel:67f85f2b00001360/67f85f2b00001771
  term: PomBase:SPBC119.01
- id: gomodel:67f85f2b00001360/67f85f2b00001725
  term: PomBase:SPAC3A11.12c
objects:
- id: GO:0008233
  label: peptidase activity
  type: gocam:Object
- id: GO:0005839
  label: proteasome core complex
  type: gocam:Object
- id: GO:0043161
  label: proteasome-mediated ubiquitin-dependent protein catabolic process
  type: gocam:Object
- id: PomBase:SPAC22F8.06
  label: pam1 Spom
  type: gocam:Object
- id: PomBase:SPAC31A2.04c
  label: pre1 Spom
  type: gocam:Object
- id: PomBase:SPCC1795.04c
  label: pre10 Spom
  type: gocam:Object
- id: PomBase:SPBC4C3.10c
  label: pre3 Spom
  type: gocam:Object
- id: PomBase:SPBC577.10
  label: pre4 Spom
  type: gocam:Object
- id: PomBase:SPAC6G10.04c
  label: pre5 Spom
  type: gocam:Object
- id: PomBase:SPBC106.16
  label: pre6 Spom
  type: gocam:Object
- id: PomBase:SPCC1442.06
  label: pre8 Spom
  type: gocam:Object
- id: PomBase:SPAC13C5.01c
  label: pre9 Spom
  type: gocam:Object
- id: PomBase:SPAC4A8.13c
  label: pts1 Spom
  type: gocam:Object
- id: PomBase:SPAC23D3.07
  label: pup1 Spom
  type: gocam:Object
- id: PomBase:SPAC323.02c
  label: pup2 Spom
  type: gocam:Object
- id: PomBase:SPCC63.12c
  label: pup3 Spom
  type: gocam:Object
- id: PomBase:SPBC646.16
  label: scl1 Spom
  type: gocam:Object
- id: GO:0036402
  label: proteasome-activating activity
  type: gocam:Object
- id: GO:0008540
  label: proteasome regulatory particle, base subcomplex
  type: gocam:Object
- id: PomBase:SPBP19A11.03c
  label: mts4 Spom
  type: gocam:Object
- id: PomBase:SPAC637.10c
  label: rpn10 Spom
  type: gocam:Object
- id: PomBase:SPBC17D11.07c
  label: rpn2 Spom
  type: gocam:Object
- id: PomBase:SPBC16C6.07c
  label: rpt1 Spom
  type: gocam:Object
- id: PomBase:SPBC4.07c
  label: rpt2 Spom
  type: gocam:Object
- id: PomBase:SPCC576.10c
  label: rpt3 Spom
  type: gocam:Object
- id: PomBase:SPCC1682.16
  label: rpt4 Spom
  type: gocam:Object
- id: PomBase:SPAC3A11.12c
  label: rpt5 Spom
  type: gocam:Object
- id: PomBase:SPBC23G7.12c
  label: rpt6 Spom
  type: gocam:Object
- id: GO:0140492
  label: metal-dependent deubiquitinase activity
  type: gocam:Object
- id: GO:0008541
  label: proteasome regulatory particle, lid subcomplex
  type: gocam:Object
- id: PomBase:SPAC31G5.13
  label: rpn11 Spom
  type: gocam:Object
- id: PomBase:SPBC16G5.01
  label: rpn12 Spom
  type: gocam:Object
- id: PomBase:SPBC342.04
  label: rpn1301 Spom
  type: gocam:Object
- id: PomBase:SPCC16A11.16c
  label: rpn1302 Spom
  type: gocam:Object
- id: PomBase:SPBC119.01
  label: rpn3 Spom
  type: gocam:Object
- id: PomBase:SPAC1420.03
  label: rpn501 Spom
  type: gocam:Object
- id: PomBase:SPAPB8E5.02c
  label: rpn502 Spom
  type: gocam:Object
- id: PomBase:SPAC23G3.11
  label: rpn6 Spom
  type: gocam:Object
- id: PomBase:SPBC582.07c
  label: rpn7 Spom
  type: gocam:Object
- id: PomBase:SPCC1682.10
  label: rpn8 Spom
  type: gocam:Object
- id: PomBase:SPAC607.05
  label: rpn9 Spom
  type: gocam:Object
- id: GO:0044183
  label: protein folding chaperone
  type: gocam:Object
- id: PomBase:SPCC14G10.03c
  label: ump1 Spom
  type: gocam:Object
- id: GO:0043248
  label: proteasome assembly
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: ECO:0000307
  label: no evidence data found used in manual assertion
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: GO:0003674
  label: molecular_function
  type: gocam:Object
- id: PomBase:SPBC16E9.19
  label: pac3 Spom
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPCC24B10.16c
  label: pac4 Spom
  type: gocam:Object
- id: ECO:0000303
  label: author statement without traceable support used in manual assertion
  type: gocam:Object
- id: ECO:0000316
  label: genetic interaction evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPAC2H10.02c
  label: nas2 Spom
  type: gocam:Object
- id: GO:0070682
  label: proteasome regulatory particle assembly
  type: gocam:Object
- id: PomBase:SPAC6C3.08
  label: nas6 Spom
  type: gocam:Object
- id: ECO:0000304
  label: author statement supported by traceable reference used in manual assertion
  type: gocam:Object
- id: PomBase:SPAC3G6.02
  label: dss1 Spom
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPCC18.17c
  label: hsm3 Spom
  type: gocam:Object
- id: ECO:0000250
  label: sequence similarity evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000244
  label: combinatorial evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0000-0001-6330-7526
  date: '2026-03-19'
  provided_by:
  - http://www.pombase.org
