id: gomodel:69a0c46f00003691
title: pyrimidine nucleobase metabolic process (GO:0006206)
taxon: NCBITaxon:4896
status: production
date_modified: '2026-03-16'
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    type: CellularAnatomicalEntityAssociation
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objects:
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  label: carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
  type: gocam:Object
- id: PomBase:SPAC22G7.06c
  label: ura1 Spom
  type: gocam:Object
- id: GO:0006207
  label: '''de novo'' pyrimidine nucleobase biosynthetic process'
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: ECO:0000316
  label: genetic interaction evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:58359
  label: L-glutamine zwitterion
  type: gocam:Object
- id: CHEBI:58228
  label: carbamoyl phosphate(2-)
  type: gocam:Object
- id: CHEBI:29985
  label: L-glutamate(1-)
  type: gocam:Object
- id: GO:0004070
  label: aspartate carbamoyltransferase activity
  type: gocam:Object
- id: CHEBI:29991
  label: L-aspartate(1-)
  type: gocam:Object
- id: CHEBI:32814
  label: N-carbamoyl-L-aspartate(2-)
  type: gocam:Object
- id: GO:0004151
  label: dihydroorotase activity
  type: gocam:Object
- id: PomBase:SPAC16.03c
  label: ura2 Spom
  type: gocam:Object
- id: GO:0005737
  label: cytoplasm
  type: gocam:Object
- id: CHEBI:30864
  label: (S)-dihydroorotate
  type: gocam:Object
- id: GO:0106430
  label: dihydroorotate dehydrogenase (quinone) activity
  type: gocam:Object
- id: PomBase:SPAC57A10.12c
  label: ura3 Spom
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:16389
  label: ubiquinones
  type: gocam:Object
- id: GO:0005743
  label: mitochondrial inner membrane
  type: gocam:Object
- id: GO:0008121
  label: quinol-cytochrome-c reductase activity
  type: gocam:Object
- id: GO:0045275
  label: respiratory chain complex III
  type: gocam:Object
- id: PomBase:SPCC737.02c
  label: qcr7 Spom
  type: gocam:Object
- id: PomBase:SPMIT.05
  label: cob1 Spom
  type: gocam:Object
- id: PomBase:SPBP4H10.08
  label: qcr10 Spom
  type: gocam:Object
- id: PomBase:SPAC1782.07
  label: qcr8 Spom
  type: gocam:Object
- id: PomBase:SPCC1682.01
  label: qcr9 Spom
  type: gocam:Object
- id: PomBase:SPBC16C6.08c
  label: qcr6 Spom
  type: gocam:Object
- id: PomBase:SPBC16H5.06
  label: rip1 Spom
  type: gocam:Object
- id: PomBase:SPBC29A3.18
  label: cyt1 Spom
  type: gocam:Object
- id: PomBase:SPCC613.10
  label: qcr2 Spom
  type: gocam:Object
- id: GO:0006122
  label: mitochondrial electron transport, ubiquinol to cytochrome c
  type: gocam:Object
- id: ECO:0000303
  label: author statement without traceable support used in manual assertion
  type: gocam:Object
- id: CHEBI:17976
  label: ubiquinol
  type: gocam:Object
- id: CHEBI:30839
  label: orotate
  type: gocam:Object
- id: GO:0004588
  label: orotate phosphoribosyltransferase activity
  type: gocam:Object
- id: PomBase:SPBC725.15
  label: ura5 Spom
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:58017
  label: 5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-)
  type: gocam:Object
- id: CHEBI:57538
  label: orotidine 5'-phosphate(3-)
  type: gocam:Object
- id: GO:0004590
  label: orotidine-5'-phosphate decarboxylase activity
  type: gocam:Object
- id: PomBase:SPCC330.05c
  label: ura4 Spom
  type: gocam:Object
- id: GO:0044205
  label: '''de novo'' UMP biosynthetic process'
  type: gocam:Object
- id: CHEBI:57865
  label: uridine 5'-monophosphate(2-)
  type: gocam:Object
- id: GO:0033862
  label: UMP kinase activity
  type: gocam:Object
- id: PomBase:SPCC1795.05c
  label: ura6 Spom
  type: gocam:Object
- id: GO:0006225
  label: UDP biosynthetic process
  type: gocam:Object
- id: CHEBI:58223
  label: UDP(3-)
  type: gocam:Object
- id: CHEBI:30616
  label: ATP(4-)
  type: gocam:Object
- id: CHEBI:456216
  label: ADP(3-)
  type: gocam:Object
- id: GO:0004550
  label: nucleoside diphosphate kinase activity
  type: gocam:Object
- id: PomBase:SPAC806.07
  label: ndk1 Spom
  type: gocam:Object
- id: GO:0006228
  label: UTP biosynthetic process
  type: gocam:Object
- id: CHEBI:46398
  label: UTP(4-)
  type: gocam:Object
- id: GO:0003883
  label: CTP synthase activity
  type: gocam:Object
- id: PomBase:SPAC10F6.03c
  label: cts1 Spom
  type: gocam:Object
- id: GO:0006241
  label: CTP biosynthetic process
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:37563
  label: CTP(4-)
  type: gocam:Object
- id: CHEBI:58069
  label: CDP(3-)
  type: gocam:Object
- id: GO:0036430
  label: CMP kinase activity
  type: gocam:Object
- id: CHEBI:36080
  label: protein
  type: gocam:Object
- id: GO:0046705
  label: CDP biosynthetic process
  type: gocam:Object
- id: CHEBI:60377
  label: cytidine 5'-monophosphate(2-)
  type: gocam:Object
- id: GO:0008253
  label: 5'-nucleotidase activity
  type: gocam:Object
- id: PomBase:SPAC24B11.05
  label: ifn1 Spom
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  label: pyrimidine nucleobase metabolic process
  type: gocam:Object
- id: ECO:0000255
  label: match to sequence model evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:17562
  label: cytidine
  type: gocam:Object
- id: CHEBI:16704
  label: uridine
  type: gocam:Object
- id: GO:0004849
  label: uridine kinase activity
  type: gocam:Object
- id: PomBase:SPCC162.11c
  label: urk1 Spom
  type: gocam:Object
- id: GO:0043771
  label: cytidine kinase activity
  type: gocam:Object
- id: PomBase:SPAC227.14
  label: yfh7 Spom
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: CHEBI:17568
  label: uracil
  type: gocam:Object
- id: GO:0004845
  label: uracil phosphoribosyltransferase activity
  type: gocam:Object
- id: PomBase:SPAC1399.04c
  label: uck2 Spom
  type: gocam:Object
- id: PomBase:SPAC1002.17c
  label: urg2 Spom
  type: gocam:Object
- id: PomBase:SPAC1B3.01c
  label: SPAC1B3.01c Spom
  type: gocam:Object
- id: GO:0006223
  label: uracil salvage
  type: gocam:Object
- id: GO:0045437
  label: uridine nucleosidase activity
  type: gocam:Object
- id: PomBase:SPBC1683.06c
  label: urh1 Spom
  type: gocam:Object
- id: GO:0046135
  label: pyrimidine nucleoside catabolic process
  type: gocam:Object
- id: PomBase:SPAC17G8.02
  label: urh2 Spom
  type: gocam:Object
- id: CHEBI:47013
  label: D-ribofuranose
  type: gocam:Object
- id: GO:0004131
  label: cytosine deaminase activity
  type: gocam:Object
- id: PomBase:SPCC965.14c
  label: fcy1 Spom
  type: gocam:Object
- id: GO:0019858
  label: cytosine metabolic process
  type: gocam:Object
- id: CHEBI:16040
  label: cytosine
  type: gocam:Object
- id: CHEBI:28938
  label: ammonium
  type: gocam:Object
- id: GO:0050263
  label: ribosylpyrimidine nucleosidase activity
  type: gocam:Object
- id: GO:0004126
  label: cytidine deaminase activity
  type: gocam:Object
- id: PomBase:SPAC1556.04c
  label: cdd1 Spom
  type: gocam:Object
- id: GO:0046109
  label: uridine biosynthetic process
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0009-0003-9059-1333
  date: '2026-03-16'
  provided_by:
  - http://www.pombase.org
