id: gomodel:678073a900002636
title: coenzyme A biosynthetic process (GO:0015937) and acetyl-CoA biosynthetic process
  (GO:0006085)
taxon: NCBITaxon:4896
status: production
date_modified: '2026-04-27'
comments:
- 'Automated change 2026-03-26: GO:0019427 replaced by GO:0006085'
activities:
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  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0009-0003-9059-1333
      date: '2025-06-09'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
objects:
- id: GO:0003987
  label: acetyl-CoA synthetase activity
  type: gocam:Object
- id: PomBase:SPCC191.02c
  label: acs1 Spom
  type: gocam:Object
- id: GO:0006085
  label: acetyl-CoA biosynthetic process
  type: gocam:Object
- id: GO:0005759
  label: mitochondrial matrix
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: CHEBI:58342
  label: acyl-CoA(4-)
  type: gocam:Object
- id: GO:0008775
  label: acetate CoA-transferase activity
  type: gocam:Object
- id: PomBase:SPAC1952.09c
  label: ach1 Spom
  type: gocam:Object
- id: ECO:0000304
  label: author statement supported by traceable reference used in manual assertion
  type: gocam:Object
- id: GO:0004140
  label: dephospho-CoA kinase activity
  type: gocam:Object
- id: PomBase:SPCC14G10.01
  label: cab5 Spom
  type: gocam:Object
- id: GO:0015937
  label: coenzyme A biosynthetic process
  type: gocam:Object
- id: GO:0004595
  label: pantetheine-phosphate adenylyltransferase activity
  type: gocam:Object
- id: PomBase:SPAC1F12.08
  label: cab4 Spom
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: GO:0004633
  label: phosphopantothenoylcysteine decarboxylase activity
  type: gocam:Object
- id: PomBase:SPAC15E1.04
  label: hal3 Spom
  type: gocam:Object
- id: ECO:0000314
  label: direct assay evidence used in manual assertion
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: GO:0004632
  label: phosphopantothenate--cysteine ligase activity
  type: gocam:Object
- id: PomBase:SPCC4B3.18
  label: ppc1 Spom
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: GO:0004594
  label: pantothenate kinase activity
  type: gocam:Object
- id: PomBase:SPBC4B4.01c
  label: ptk1 Spom
  type: gocam:Object
- id: CHEBI:29032
  label: (R)-pantothenate
  type: gocam:Object
- id: CHEBI:57287
  label: coenzyme A(4-)
  type: gocam:Object
- id: CHEBI:30089
  label: acetate
  type: gocam:Object
- id: CHEBI:57288
  label: acetyl-CoA(4-)
  type: gocam:Object
- id: GO:0015228
  label: coenzyme A transmembrane transporter activity
  type: gocam:Object
- id: PomBase:SPAC17H9.08
  label: leu5 Spom
  type: gocam:Object
- id: GO:1990559
  label: mitochondrial coenzyme A transmembrane transport
  type: gocam:Object
- id: GO:0005743
  label: mitochondrial inner membrane
  type: gocam:Object
- id: CHEBI:35235
  label: L-cysteine zwitterion
  type: gocam:Object
- id: CHEBI:29067
  label: carboxylic acid anion
  type: gocam:Object
- id: CHEBI:10986
  label: (R)-4'-phosphonatopantothenate(3-)
  type: gocam:Object
- id: CHEBI:59458
  label: N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate(3-)
  type: gocam:Object
- id: CHEBI:61723
  label: D-pantetheine 4'-phosphate(2-)
  type: gocam:Object
- id: CHEBI:57328
  label: 3'-dephospho-CoA(2-)
  type: gocam:Object
- id: GO:0031315
  label: extrinsic component of mitochondrial outer membrane
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0009-0003-9059-1333
  date: '2026-04-27'
  provided_by:
  - http://www.pombase.org
