id: gomodel:6994852c00004096
title: "protein import into mitochondrial intermembrane space\n (GO:0045041)"
taxon: NCBITaxon:4896
status: production
date_modified: '2026-04-08'
activities:
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        date: '2026-02-25'
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        date: '2026-02-25'
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      date: '2026-02-25'
      provided_by:
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    term: PomBase:SPAC17H9.16
    part_of:
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      evidence:
      - term: ECO:0000266
        reference: GO_REF:0000024
        with_objects:
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      term: GO:0140596
  molecular_function:
    type: MolecularFunctionAssociation
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    evidence:
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      reference: GO_REF:0000002
      with_objects:
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    term: GO:0005741
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    term: GO:0045041
  causal_associations:
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    downstream_activity: gomodel:6994852c00004096/6994852c00004097
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      date: '2026-03-13'
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    term: PomBase:SPAC22E12.04
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0016532
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    term: GO:0051604
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    term: PomBase:SPAC3G6.08
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      provided_by:
      - http://www.pombase.org
    term: PomBase:SPAC17H9.16
    part_of:
    - type: PartOfProteinComplexAssociation
      evidence:
      - term: ECO:0000266
        reference: GO_REF:0000024
        with_objects:
        - SGD:S000005075
        provenances:
        - contributor:
          - https://orcid.org/0000-0001-6330-7526
          date: '2026-02-25'
          provided_by:
          - http://www.pombase.org
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-02-25'
        provided_by:
        - http://www.pombase.org
      term: GO:0140596
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0003674
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000501
      reference: GO_REF:0000002
      with_objects:
      - InterPro:IPR005683
      - InterPro:IPR020951
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-02-25'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-25'
      provided_by:
      - http://www.pombase.org
    term: GO:0005741
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000305
      reference: GO_REF:0000111
      with_objects:
      - GO:0140596
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-04-08'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-04-08'
      provided_by:
      - http://www.pombase.org
    term: GO:0045041
- id: gomodel:6994852c00004096/6994852c00004111
  enabled_by:
    type: EnabledByGeneProductAssociation
    evidence:
    - term: ECO:0000307
      reference: GO_REF:0000015
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-02-25'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-25'
      provided_by:
      - http://www.pombase.org
    term: PomBase:SPAC17H9.16
    part_of:
    - type: PartOfProteinComplexAssociation
      evidence:
      - term: ECO:0000266
        reference: GO_REF:0000024
        with_objects:
        - SGD:S000005075
        provenances:
        - contributor:
          - https://orcid.org/0000-0001-6330-7526
          date: '2026-02-25'
          provided_by:
          - http://www.pombase.org
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-02-25'
        provided_by:
        - http://www.pombase.org
      term: GO:0140596
  molecular_function:
    type: MolecularFunctionAssociation
    term: GO:0003674
  occurs_in:
    type: CellularAnatomicalEntityAssociation
    evidence:
    - term: ECO:0000501
      reference: GO_REF:0000002
      with_objects:
      - InterPro:IPR005683
      - InterPro:IPR020951
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-02-25'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-02-25'
      provided_by:
      - http://www.pombase.org
    term: GO:0005741
  part_of:
    type: BiologicalProcessAssociation
    evidence:
    - term: ECO:0000305
      reference: GO_REF:0000111
      with_objects:
      - GO:0140596
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-04-08'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-04-08'
      provided_by:
      - http://www.pombase.org
    term: GO:0045041
molecules:
- id: gomodel:6994852c00004096/6994852c00006044
  term: PomBase:SPAC17C9.09c
- id: gomodel:6994852c00004096/69b3372b00000927
  term: PomBase:SPBC21D10.07
- id: gomodel:6994852c00004096/6994852c00006043
  term: PomBase:SPAC222.03c
- id: gomodel:6994852c00004096/69b3372b00000926
  term: PomBase:SPCC4B3.20
- id: gomodel:6994852c00004096/69b3372b00000659
  term: CHEBI:29950
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0005758
- id: gomodel:6994852c00004096/69b3372b00000690
  term: CHEBI:15379
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0005758
- id: gomodel:6994852c00004096/69b3372b00000692
  term: CHEBI:16240
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0005758
- id: gomodel:6994852c00004096/69b3372b00000917
  term: PomBase:SPBC119.18
- id: gomodel:6994852c00004096/6994852c00006042
  term: PomBase:SPBC26H8.14c
- id: gomodel:6994852c00004096/69b3372b00000729
  term: PomBase:SPAC821.10c
- id: gomodel:6994852c00004096/69b3372b00000920
  term: PomBase:SPAC4F10.22
- id: gomodel:6994852c00004096/69b3372b00000919
  term: PomBase:SPAC3G6.08
- id: gomodel:6994852c00004096/69b3372b00000922
  term: PomBase:SPCC1672.04c
- id: gomodel:6994852c00004096/69b3372b00000722
  term: PomBase:SPAC22E12.04
- id: gomodel:6994852c00004096/69b3372b00000918
  term: PomBase:SPAC57A10.11c
- id: gomodel:6994852c00004096/69b3372b00000671
  term: CHEBI:50058
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-13'
      provided_by:
      - http://www.pombase.org
    term: GO:0005758
- id: gomodel:6994852c00004096/69b3372b00000921
  term: PomBase:SPBC1718.06
- id: gomodel:6994852c00004096/6994852c00006046
  term: PomBase:SPCC24B10.05
- id: gomodel:6994852c00004096/69b3372b00000925
  term: PomBase:SPCC550.01c
- id: gomodel:6994852c00004096/69a0c46f00001759
  term: PomBase:SPCC320.12
- id: gomodel:6994852c00004096/6994852c00006045
  term: PomBase:SPAC13G6.04
- id: gomodel:6994852c00004096/69b3372b00000924
  term: PomBase:SPBC16A3.16
- id: gomodel:6994852c00004096/69b3372b00000689
  term: PomBase:SPAC57A10.11c
- id: gomodel:6994852c00004096/69b3372b00000923
  term: PomBase:SPBC24C6.13
- id: gomodel:6994852c00004096/69b3372b00000723
  term: PomBase:SPAC821.10c
objects:
- id: PomBase:SPCC320.12
  label: atp23 Spom
  type: gocam:Object
- id: ECO:0000304
  label: author statement supported by traceable reference used in manual assertion
  type: gocam:Object
- id: GO:0008270
  label: zinc ion binding
  type: gocam:Object
- id: PomBase:SPAC29B12.12
  label: hot13 Spom
  type: gocam:Object
- id: GO:0045041
  label: protein import into mitochondrial intermembrane space
  type: gocam:Object
- id: GO:0005758
  label: mitochondrial intermembrane space
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPBC3B9.05
  label: hot15 Spom
  type: gocam:Object
- id: CHEBI:29950
  label: L-cysteine residue
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: CHEBI:50058
  label: L-cystine residue
  type: gocam:Object
- id: GO:0015035
  label: protein-disulfide reductase activity
  type: gocam:Object
- id: PomBase:SPAC3G6.08
  label: erv1 Spom
  type: gocam:Object
- id: GO:0160203
  label: protein import into the intermembrane space via the disulfide relay system
  type: gocam:Object
- id: ECO:0000266
  label: sequence orthology evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPAC57A10.11c
  label: mia40 Spom
  type: gocam:Object
- id: CHEBI:15379
  label: dioxygen
  type: gocam:Object
- id: CHEBI:16240
  label: hydrogen peroxide
  type: gocam:Object
- id: GO:0016697
  label: oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor
  type: gocam:Object
- id: GO:0006123
  label: mitochondrial electron transport, cytochrome c to oxygen
  type: gocam:Object
- id: GO:0009055
  label: electron transfer activity
  type: gocam:Object
- id: PomBase:SPCC191.07
  label: cyc1 Spom
  type: gocam:Object
- id: PomBase:SPAC22E12.04
  label: ccs1 Spom
  type: gocam:Object
- id: PomBase:SPAC821.10c
  label: sod1 Spom
  type: gocam:Object
- id: GO:0016532
  label: superoxide dismutase copper chaperone activity
  type: gocam:Object
- id: ECO:0000315
  label: mutant phenotype evidence used in manual assertion
  type: gocam:Object
- id: PomBase:SPBC119.18
  label: mdm35 Spom
  type: gocam:Object
- id: PomBase:SPAC4F10.22
  label: cmc4 Spom
  type: gocam:Object
- id: PomBase:SPBC1718.06
  label: msp1 Spom
  type: gocam:Object
- id: PomBase:SPCC1672.04c
  label: cox19 Spom
  type: gocam:Object
- id: PomBase:SPBC24C6.13
  label: coa6 Spom
  type: gocam:Object
- id: PomBase:SPBC16A3.16
  label: coa5 Spom
  type: gocam:Object
- id: PomBase:SPCC550.01c
  label: coa4 Spom
  type: gocam:Object
- id: PomBase:SPCC4B3.20
  label: cmc1 Spom
  type: gocam:Object
- id: PomBase:SPBC21D10.07
  label: cmc2 Spom
  type: gocam:Object
- id: ECO:0000305
  label: curator inference used in manual assertion
  type: gocam:Object
- id: GO:0051604
  label: protein maturation
  type: gocam:Object
- id: GO:0008320
  label: transmembrane protein transporter activity
  type: gocam:Object
- id: PomBase:SPBC27B12.13
  label: tom40 Spom
  type: gocam:Object
- id: GO:0005741
  label: mitochondrial outer membrane
  type: gocam:Object
- id: GO:0140596
  label: TOM complex
  type: gocam:Object
- id: GO:0003674
  label: molecular_function
  type: gocam:Object
- id: PomBase:SPBC19G7.19
  label: tom5 Spom
  type: gocam:Object
- id: PomBase:SPAC17H9.16
  label: tom22 Spom
  type: gocam:Object
- id: PomBase:SPAC823.17
  label: tom6 Spom
  type: gocam:Object
- id: ECO:0000307
  label: no evidence data found used in manual assertion
  type: gocam:Object
- id: PomBase:SPBC27B12.10c
  label: tom7 Spom
  type: gocam:Object
- id: GO:0030943
  label: mitochondrion targeting sequence binding
  type: gocam:Object
- id: PomBase:SPAC6F12.07
  label: tom20 Spom
  type: gocam:Object
- id: PomBase:SPBC26H8.14c
  label: cox17 Spom
  type: gocam:Object
- id: PomBase:SPAC222.03c
  label: tim10 Spom
  type: gocam:Object
- id: PomBase:SPAC17C9.09c
  label: tim13 Spom
  type: gocam:Object
- id: PomBase:SPAC13G6.04
  label: tim8 Spom
  type: gocam:Object
- id: PomBase:SPCC24B10.05
  label: tim9 Spom
  type: gocam:Object
- id: GO:0016971
  label: flavin-dependent sulfhydryl oxidase activity
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0000-0001-6330-7526
  date: '2026-04-08'
  provided_by:
  - http://www.pombase.org
