id: gomodel:69c59f8a00000584
title: L-methionine cycle (GO:0033353)
taxon: NCBITaxon:4896
status: production
date_modified: '2026-03-28'
activities:
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      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69c59f8a00000584/69c59f8a00000623
  - type: MoleculeAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002233
    molecule: gomodel:69c59f8a00000584/69c59f8a00000623
  - type: MoleculeAssociation
    evidence:
    - term: ECO:0000501
      reference: GO_REF:0000003
      with_objects:
      - EC:5.3.1.23
      provenances:
      - contributor:
        - https://orcid.org/0000-0001-6330-7526
        date: '2026-03-28'
        provided_by:
        - http://www.pombase.org
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    predicate: RO:0002234
    molecule: gomodel:69c59f8a00000584/69c59f8a00000621
molecules:
- id: gomodel:69c59f8a00000584/69c59f8a00000669
  term: CHEBI:58828
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
- id: gomodel:69c59f8a00000584/69c59f8a00000621
  term: CHEBI:58548
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
- id: gomodel:69c59f8a00000584/69c59f8a00000704
  term: CHEBI:49252
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
- id: gomodel:69c59f8a00000584/69c59f8a00000623
  term: CHEBI:58533
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
- id: gomodel:69c59f8a00000584/69c59f8a00000721
  term: CHEBI:16723
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
- id: gomodel:69c59f8a00000584/69c59f8a00000615
  term: CHEBI:17509
  located_in:
    type: CellularAnatomicalEntityAssociation
    evidence: []
    provenances:
    - contributor:
      - https://orcid.org/0000-0001-6330-7526
      date: '2026-03-28'
      provided_by:
      - http://www.pombase.org
    term: GO:0005829
objects:
- id: GO:0010309
  label: acireductone dioxygenase [iron(II)-requiring] activity
  type: gocam:Object
- id: PomBase:SPBC887.01
  label: adi1 Spom
  type: gocam:Object
- id: GO:0033353
  label: L-methionine cycle
  type: gocam:Object
- id: GO:0005829
  label: cytosol
  type: gocam:Object
- id: ECO:0000501
  label: evidence used in automatic assertion
  type: gocam:Object
- id: ECO:0000255
  label: match to sequence model evidence used in manual assertion
  type: gocam:Object
- id: ECO:0007005
  label: high throughput direct assay evidence used in manual assertion
  type: gocam:Object
- id: GO:0017061
  label: S-methyl-5-thioadenosine phosphorylase activity
  type: gocam:Object
- id: PomBase:SPAC16C9.02c
  label: mta1 Spom
  type: gocam:Object
- id: ECO:0000318
  label: biological aspect of ancestor evidence used in manual assertion
  type: gocam:Object
- id: GO:0046523
  label: S-methyl-5-thioribose-1-phosphate isomerase activity
  type: gocam:Object
- id: PomBase:SPBC23E6.10c
  label: mri1 Spom
  type: gocam:Object
- id: CHEBI:17509
  label: 5'-S-methyl-5'-thioadenosine
  type: gocam:Object
- id: CHEBI:58548
  label: S-methyl-5-thio-D-ribulose 1-phosphate(2-)
  type: gocam:Object
- id: CHEBI:58533
  label: S-methyl-5-thio-alpha-D-ribose 1-phosphate(2-)
  type: gocam:Object
- id: GO:0046570
  label: methylthioribulose 1-phosphate dehydratase activity
  type: gocam:Object
- id: PomBase:SPAC20H4.05c
  label: mde1 Spom
  type: gocam:Object
- id: CHEBI:58828
  label: 5-(methylsulfanyl)-2,3-dioxopentyl phosphate(2-)
  type: gocam:Object
- id: PomBase:SPAC9.06c
  label: mta3 Spom
  type: gocam:Object
- id: GO:0005737
  label: cytoplasm
  type: gocam:Object
- id: GO:0043874
  label: acireductone synthase activity
  type: gocam:Object
- id: PomBase:SPAC644.08
  label: utr4 Spom
  type: gocam:Object
- id: CHEBI:49252
  label: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one
  type: gocam:Object
- id: CHEBI:16723
  label: 4-methylthio-2-oxobutanoate
  type: gocam:Object
provenances:
- contributor:
  - https://orcid.org/0000-0001-6330-7526
  date: '2026-03-28'
  provided_by:
  - http://www.pombase.org
