[Recombinational repair in Schizosaccharomyces pombe: the role of mediator proteins].
Repair of double-stranded DNA breaks that occur spontaneously or under the influence of external factors, are critical for cell survival. Evolutionarily conserved mechanism for error-free recombinational repair plays a major role in maintaining genome integrity. Repair pathway is conservative and has a number of similarities in lower eukaryotes and vertebrates. This review examines the current state of studying the mechanism of recombinational repair double-stranded DNA breaks in the fission yeast Schizosaccharomyces pombe, notes the differences of this type of repair in Saccharomyces cerevisiae and higher eukaryotes.
Khasanova OS, Vagin DA, Khasanov FK