A two-way street: LSD1 regulates chromatin boundary formation in S. pombe and Drosophila.
Two recent studies in Molecular Cell (Lan et al., 2007; Rudolph et al., 2007) implicate histone demethylation by LSD1 in the regulation of boundaries between silenced and active chromatin domains in both fission yeast and flies, but by distinct mechanisms.
Chosed R, Dent SY