Synonymous mutations in the phosphoglycerate kinase 1 gene induce an altered response to protein misfolding in  Schizosaccharomyces pombe .
Taken together, these data suggest that codon usage bias of the gene encoding this highly-expressed protein is an important regulator of protein function and proteostasis.
Moreira-Ramos S, Arias L, Flores R, Katz A, Levicán G, Orellana O