tricarboxylic acid cycle
Krebs cycle
exact
TCA cycle
exact
citric acid cycle
exact
oxidative TCA cycle
exact
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
GO:0044238
primary metabolic process
is_a
GO:0009060
aerobic respiration
part_of
SPAC1556.02c SPBP23A10.16 SPCC18.18c SPCC330.12c SPAC140.01 SPAC6G10.08 SPAC11G7.03 SPAC6C3.04 SPCC306.08c SPAC24C9.06c SPBC21B10.14 SPBP4H10.15 SPBC3H7.03c SPAC16E8.17c SPBC776.15c SPCC1620.08 SPBC902.05c