keratan sulfate proteoglycan biosynthetic process
keratan sulfate anabolism
exact
keratan sulfate biosynthesis
exact
keratan sulfate formation
exact
keratan sulfate synthesis
exact
keratan sulphate biosynthesis
exact
keratan sulphate biosynthetic process
exact
The chemical reactions and pathways resulting in the formation of keratan sulfate proteoglycans, which consist of a core protein linked to a keratan sulfate glycosaminoglycan. The keratan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-beta-(1,3)-galactose, both of which can be sulfated. Keratan sulfate chains can be covalently linked either to an asparagine residue (N-linked) of the core protein via a high mannose oligasacccharide linker or to serine/threonine residues (O-linked) of the core protein via a core 2 type-linker.
GO:0030166
proteoglycan biosynthetic process
is_a
GO:0042339
keratan sulfate proteoglycan metabolic process
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