Prp19 complex
MOS4-Associated Complex
narrow
NTC
related
Prp19/CDC5 complex
narrow
nineteen complex
narrow
A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p.
GO:0032991
protein-containing complex
is_a
SPBC146.05c SPAC57A10.03 SPCC550.02c SPCP1E11.07c SPAC2C4.03c SPAC4F8.12c SPAC3A12.11c SPBP22H7.07 SPAC644.12 SPAC9.13c SPBC337.06c SPBC6B1.10 SPAC29A4.08c SPBC24C6.11 SPAC30D11.09 SPBC211.02c SPBC31F10.11c SPAC4A8.09c SPBC28F2.04c SPCC1620.10 SPAC1F3.09 SPBC215.12 SPBC32F12.05c SPCC188.11 SPBC646.02 SPBC3E7.13c SPBC13E7.01