transcription coactivator activity
RNA polymerase II transcription co-activator activity
related
RNA polymerase II transcription coactivator activity
related
RNA polymerase II transcription mediator activity
related
transcription co-activator activity
exact
A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-binding transcription factor at a specific genomic locus, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator.
GO:0003712
transcription coregulator activity
is_a
SPCC1682.13 SPBC887.18c SPBC21.04 SPAC22H10.11c SPBC21B10.13c SPCC126.04c SPBC6B1.12c SPAC688.08 SPBC14C8.17c SPAC2F7.04 SPAC5D6.05 SPBC28F2.10c SPAC30D11.08c SPAC17C9.05c SPBC25H2.11c SPAC1952.05 SPBP16F5.03c SPBC2D10.06 SPCC16C4.18c SPAC8C9.11 SPCC61.02 SPBC31F10.09c SPBC1604.10 SPBC26H8.06 SPAC29B12.11c SPBC83.17 SPCC24B10.08c SPBC29A10.12 SPBC2F12.11c SPAC16A10.02 SPAC1002.15c SPAC23E2.02 SPBC31F10.04c SPBC1921.07c SPBC1A4.10c SPCC5E4.03c SPAC57A10.14 SPAC4D7.10c SPAC15A10.02 SPAC23H4.17c SPAC17G8.05 SPAC29A4.07 SPAC26H5.05 SPCC1450.05c SPBC146.01 SPBC23G7.09 SPAC589.02c SPAC24C9.04 SPAC12G12.05c SPBC1105.06 SPBC12D12.06 SPAC644.10 SPAC13A11.04c SPBC21H7.02 SPCP31B10.03c SPAC14C4.12c SPBC14F5.08