Parkinson disease
PD
exact
Parkinson disease
exact
Parkinson's disease
exact
paralysis agitans
exact
A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression.
MONDO:0000510
synucleinopathy
excluded_subClassOf
MONDO:0021095
parkinsonian disorder
is_a
MONDO:0100545
hereditary neurological disease
is_a
SPAC6C3.02c SPAP27G11.05c SPAC1782.05 SPCC777.13 SPBC2G2.02 SPAC22E12.03c SPAC4F10.04 SPAC29E6.08 SPCC1672.11c SPBC21C3.01c SPBC21B10.03c SPBC16C6.02c SPBC577.13 SPAC29A4.19c