guanyl-nucleotide exchange factor activity
ARF guanyl-nucleotide exchange factor activity
narrow
GDP-dissociation stimulator activity
exact
GDS
exact
GEF
exact
GNRP
narrow
Rab guanyl-nucleotide exchange factor activity
narrow
Rac guanyl-nucleotide exchange factor activity
narrow
Ral guanyl-nucleotide exchange factor activity
narrow
Ran guanyl-nucleotide exchange factor activity
narrow
Rap guanyl-nucleotide exchange factor activity
narrow
Ras guanyl-nucleotide exchange factor activity
narrow
Rho guanine nucleotide exchange factor
exact
Rho guanyl-nucleotide exchange factor activity
narrow
RhoGEF
exact
Sar guanyl-nucleotide exchange factor activity
narrow
cAMP-dependent guanyl-nucleotide exchange factor activity
narrow
guanyl-nucleotide release factor activity
exact
guanyl-nucleotide releasing factor
exact
Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions.
GO:0030695
GTPase regulator activity
is_a
SPAC57A10.04 SPBC557.03c SPAC23C4.10 SPBC4F6.10 SPBC1778.05c SPAC23D3.13c SPAC19A8.01c SPBC3H7.01 SPAC16E8.09 SPAC31A2.16 SPBC23E6.08 SPAC3G9.16c SPCC1753.02c SPBC29A3.17 SPAC30.01c SPAC6G9.04 SPAC26F1.01 SPCC11E10.07c SPBC29A10.11c SPAC1851.04c SPAC21E11.06 SPAC4D7.01c SPAC3F10.10c SPCC285.14 SPCC1450.04 SPBC3E7.04c SPBC4C3.04c SPAC4F8.03 SPCC1494.03 SPBC800.07c SPCC1442.01 SPAC1D4.03c SPAC8C9.15c SPAC23H4.14 SPAC11E3.11c SPCC297.05 SPCC1183.12 SPCC645.06c SPAC343.14c SPAC24H6.09 SPCC645.07 SPBC2G2.03c SPCC1840.01c SPBC336.03 SPAC4A8.15c SPBC211.03c SPAC4D7.09 SPAC1006.06 SPAC1805.10 SPAC11H11.04 SPAC644.18c