extrinsic apoptotic signaling pathway
death receptor-mediated apoptosis
narrow
extrinsic apoptosis
narrow
extrinsic apoptotic pathway
exact
extrinsic apoptotic signaling pathway in presence of ligand
narrow
extrinsic apoptotic signalling pathway
exact
The series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.
GO:0007166
cell surface receptor signaling pathway
is_a
GO:0097190
apoptotic signaling pathway
is_a