DNA replication preinitiation complex
pre-IC
exact
A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present.
GO:0032993
protein-DNA complex
is_a
GO:0140513
nuclear protein-containing complex
is_a
GO:0005654
nucleoplasm
part_of
SPBP23A10.13 SPBC211.04c SPBC2A9.12 SPCC16A11.17 SPBC685.09 SPBP8B7.14c SPBC29A10.15 SPBP4H10.21c SPBP23A10.09 SPAC24H6.06 SPAC17D4.02 SPAC3H1.01c SPBC25D12.03c SPBC646.14c SPBC725.13c SPAC227.16c SPCC1682.02c SPAC23C4.18c SPAC1B2.05 SPBC4.04c