error-prone translesion synthesis
error-prone postreplication DNA repair
related
mutagenic PRR
exact
mutagenic postreplication DNA repair
related
The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites.
GO:0019985
translesion synthesis
is_a
SPBC713.02c SPAC688.10 SPBP8B7.14c SPBC16A3.11 SPBC1347.01c SPCC553.07c SPAC2F7.06c SPBC16D10.09 SPBC12D12.09