ERK5 cascade
BMK cascade
exact
BMK signaling pathway
exact
BMK signalling pathway
exact
BMK1 cascade
exact
ERK5 signaling pathway
exact
MAPK7 cascade
exact
big MAP kinase signaling cascade
exact
extracellular signal-regulated kinase 5 cascade
exact
A MAPK cascade containing at least the ERK5 MAP kinase (MAPK7; also called BMK1). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and of ERK5. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. The ERK5 cascade is activated by stress, mitogens, and by G protein-coupled receptors, and results in cellular responses such as cell growth, cell differentiation and development.
GO:0000165
MAPK cascade
is_a