leukodystrophy
hypomyelinating leukodystrophy
exact
hypomyelinating leukoencephalopathy
related
Leukodystrophies are a group of rare, progressive, metabolic, genetic diseases that affect the brain, spinal cord and often the peripheral nerves. Each type of leukodystrophy is caused by a specific gene abnormality that leads to abnormal development or destruction of the white matter (myelin sheath) of the brain. The myelin sheath is the protective covering of the nerve and nerves can't function normally without it. Each type of leukodystrophy affects a different part of the myelin sheath, leading to a range of neurological problems.
MONDO:0024237
inherited neurodegenerative disorder
is_a
SPBC1289.07c SPAC12G12.04 SPBC582.09 SPAC4G9.08c SPCC736.06 SPAC3C7.10 SPAC22A12.05 SPAC21E11.06 SPCC553.03 SPBC17A3.10 SPBC354.08c SPBC3B8.07c SPBC21H7.06c SPAPYUG7.05 SPAC17A5.15c SPBC1347.08c SPAC16A10.03c SPBC19C7.06 SPBC3B9.17 SPAC29A4.14c SPAC17C9.14 SPBC725.07 SPAC12B10.15c SPCC11E10.07c SPAC23C11.09 SPAC17D4.01 SPBC1703.08c SPAC24H6.13 SPBC16A3.06 SPBPB10D8.02c SPCC16C4.04 SPBC646.15c SPCC1223.07c SPAC823.12 SPAC30C2.04 SPAC2G11.09 SPBC4C3.05c SPBC651.08c SPAC8C9.15c SPBC13G1.03c SPAC1F12.04c SPAPB17E12.03 SPBC1198.14c SPAC4D7.09 SPAC24B11.13 SPAC17A5.01 SPAC144.12 SPAC343.14c SPAC4G9.02 SPBC26H8.07c SPBP8B7.13 SPAPB1A10.11c