protein coding gene - ctr1 (SPAC140.04) - MTREC associated protein Ctr1

Gene summary

Standard name

ctr1

Systematic ID

SPAC140.04

Product

MTREC associated protein Ctr1

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

Q9P7B7

ORFeome ID

12/12A04

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome I: 1902076..1903841 forward strand

Annotation

Protein features

Orthologs

• CCDC174 (HGNC:28033) Homo sapiens
• ctr1 (SJAG_04500) Schizosaccharomyces japonicus

References / Literature

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7

PMID:24210919 - Mtr4-like protein coordinates nuclear RNA processing for heterochromatin assembly and for telomere maintenance.

Lee NN et al. Cell 2013 Nov 21;155(5):1061-74

PMID:31219728 - Identification of proteins associated with splicing factors Ntr1, Ntr2, Brr2 and Gpl1 in the fission yeast Schizosaccharomyces pombe .

Cipakova I et al. Cell Cycle 2019 Jul;18(14):1532-1536

PMID:36361590 - Defining the Functional Interactome of Spliceosome-Associated G-Patch Protein Gpl1 in the Fission Yeast Schizosaccharomyces pombe .

Selicky T et al. Int J Mol Sci 2022 Oct 24;23(21)

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:26682798 - The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast.

Aronica L et al. Nucleic Acids Res 2016 Feb 29;44(4):1703-17

PMID:16169489 - Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast.

Gregan J et al. Curr Biol 2005 Sep 20;15(18):1663-9

PMID:27172183 - Interconnections Between RNA-Processing Pathways Revealed by a Sequencing-Based Genetic Screen for Pre-mRNA Splicing Mutants in Fission Yeast.

Larson A et al. G3 (Bethesda) 2016 Jun 01;6(6):1513-23

PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.

Rodríguez-López M et al. Elife 2023 Oct 03;12

PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:34209806 - Identification of Nrl1 Domains Responsible for Interactions with RNA-Processing Factors and Regulation of Nrl1 Function by Phosphorylation.

Mikolaskova B et al. Int J Mol Sci 2021 Jun 29;22(13)

PMID:28410370 - A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Dudin O et al. PLoS Genet 2017 Apr;13(4):e1006721

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:24713849 - Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex.

Egan ED et al. RNA 2014 Jun;20(6):867-81

PMID:25989903 - The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome.

Zhou Y et al. Nat Commun 2015 May 20;6:7050