PomBase - protein coding gene - rpl42 (SPAC15E1.03) - 60S ribosomal protein L36/L42 - The Schizosaccharomyces pombe genome database

ID	Name	InterPro name	DB name
PF00935	Ribosomal_L44	Ribosomal_eL44	Pfam
PS01172	RIBOSOMAL_L44E	Ribosomal_eL44	PROSITE patterns
G3DSA:3.10.450.80:FF:000001			CATH-FunFam
G3DSA:3.10.450.80		Ribosomal_LSU_eL42	CATH-Gene3D
SSF57829		Ribosomal_zn-bd	SUPERFAMILY
PTHR10369		Ribosomal_eL44	PANTHER
mobidb-lite-Disorder	disorder_prediction		MobiDB-Disorder

References / Literature

PMID:27984744 - Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs.: Joh RI et al. Mol Cell 2016 Dec 15;64(6):1088-1101
PMID:28775286 - Elp3 and Dph3 of Schizosaccharomyces pombe mediate cellular stress responses through tRNA Lys UUU modifications.: Villahermosa D et al. Sci Rep 2017 Aug 03;7(1):7225
PMID:29162938 - RNA metabolism is the primary target of formamide in vivo.: Hoyos-Manchado R et al. Sci Rep 2017 Nov 21;7(1):15895
PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.: Strachan J et al. J Cell Sci 2023 Dec 01;136(23)
PMID:42129552 - SNOR promotes translation restart after dormancy.: Gluc M et al. Nature 2026 May 13;
PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.: Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87
PMID:20444689 - Methylation of ribosomal protein L42 regulates ribosomal function and stress-adapted cell growth.: Shirai A et al. J Biol Chem 2010 Jul 16;285(29):22448-60
PMID:28388826 - Sulfur restriction extends fission yeast chronological lifespan through Ecl1 family genes by downregulation of ribosome.: Ohtsuka H et al. Mol Microbiol 2017 Jul;105(1):84-97
PMID:36478272 - Translation-complex profiling of fission yeast cells reveals dynamic rearrangements of scanning ribosomal subunits upon nutritional stress.: Duncan CDS et al. Nucleic Acids Res 2022 Dec 09;50(22):13011-13025
PMID:20519959 - S. pombe genome deletion project: an update.: Spirek M et al. Cell Cycle 2010 Jun 15;9(12):2399-402
PMID:25076038 - Large scale screening of genetic interaction with sgf73(+) in fission yeast.: Guo Y et al. Yi Chuan 2014 Jul;36(7):723-31
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.: Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:33313903 - Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast.: Rubio A et al. Nucleic Acids Res 2021 Jan 11;49(1):383-399
PMID:12237855 - Genome-wide search of Schizosaccharomyces pombe genes causing overexpression-mediated cell cycle defects.: Tallada VA et al. Yeast 2002 Sep 30;19(13):1139-51
PMID:34496258 - Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription.: Heo DH et al. Cell Rep 2021 Sep 07;36(10):109671
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:22730331 - Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions.: Nie M et al. J Biol Chem 2012 Aug 24;287(35):29610-9
PMID:26771498 - A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.: Vo TV et al. Cell 2016 Jan 14;164(1-2):310-323
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.: Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:36423630 - Chromatin localization of nucleophosmin organizes ribosome biogenesis.: Ugolini I et al. Mol Cell 2022 Dec 01;82(23):4443-4457.e9
PMID:39379376 - Ribosomes hibernate on mitochondria during cellular stress.: Gemin O et al. Nat Commun 2024 Oct 08;15(1):8666
PMID:30321377 - Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome.: Telekawa C et al. Nucleic Acids Res 2018 Nov 30;46(21):11169-11183
PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.: Skribbe M et al. Mol Cell 2025 Feb 19;
PMID:21511999 - Comparative functional genomics of the fission yeasts.: Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).: Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36

protein coding gene - rpl42 (SPAC15E1.03) - 60S ribosomal protein L36/L42

Gene summary

Annotation

GO biological process

GO:0002181 - cytoplasmic translation

GO cellular component

GO:0005829 - cytosol

GO:0022625 - cytosolic large ribosomal subunit

GO molecular function

GO:0003735 - structural constituent of ribosome

Modification

MOD:00427 - methylated residue

MOD:00085 - N6-methyl-L-lysine

MOD:00047 - O-phospho-L-threonine

MOD:00048 - O4'-phospho-L-tyrosine

MOD:01148 - ubiquitinylated lysine

Qualitative gene expression

PomGeneEx:0000027 - ribosomal density decreased

PomGeneEx:0000012 - RNA level decreased

Quantitative gene expression

PBO:0006310 - protein level

PBO:0011963 - RNA level

Single locus phenotype

FYPO:0001309 - increased viability in stationary phase

FYPO:0001490 - inviable elongated vegetative cell

FYPO:0004168 - normal viability in stationary phase during glucose starvation

FYPO:0000785 - sensitive to formamide

FYPO:0002060 - viable vegetative cell population

Taxonomic conservation

PBO:0011072 - conserved in archaea

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

Protein features

Orthologs

References / Literature