PomBase home

protein coding gene - ptb1 (SPAC167.02) - geranylgeranyltransferase II beta subunit Ptb1

Gene summary

Standard name
ptb1
Systematic ID
SPAC167.02
Product
geranylgeranyltransferase II beta subunit Ptb1
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
P46960
ORFeome ID
18/18F04
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome I: 1554880..1558354 reverse strand

Annotation

GO biological process

GO:0072659 - protein localization to plasma membrane

References:

GO cellular component

GO:0005829 - cytosol

References:

GO:0005634 - nucleus

References:

GO:0005968 - Rab-protein geranylgeranyltransferase complex

References:

GO molecular function

GO:0004663 - Rab geranylgeranyltransferase activity

References:

GO:0031267 - small GTPase binding

References:

GO:0008270 - zinc ion binding

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0000311 - inviable after spore germination with normal, unseptated germ tube morphology

References:

Genotypes:

FYPO:0002151 - inviable spore

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0006518 - loss of viability in G0

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

IDNameInterPro nameDB name
PF00432PrenyltransPrenyltransPfam
cd02894GGTase-IIPtb1CDD
G3DSA:1.50.10.20:FF:000012CATH-FunFam
G3DSA:1.50.10.20CATH-Gene3D
SSF48239Terpenoid_cyclase/PrenylTrfaseSUPERFAMILY
PTHR11774PGGT1B-likePANTHER

Orthologs

References / Literature

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference
PMID:19366728 - Genetic control of cellular quiescence in S. pombe.
Sajiki K et al. J Cell Sci 2009 May 01;122(Pt 9):1418-29
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623