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protein coding gene - aro7 (SPAC16E8.04c) - chorismate mutase Aro7

Gene summary

Standard name
aro7
Systematic ID
SPAC16E8.04c
Product
chorismate mutase Aro7
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
O13739
ORFeome ID
10/10D11
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome I: 3505603..3507017 reverse strand

Annotation

GO biological process

GO:0009073 - aromatic amino acid biosynthetic process

References:

GO:0009423 - chorismate biosynthetic process

References:

GO cellular component

GO:0005829 - cytosol

References:

GO:0005634 - nucleus

References:

GO molecular function

GO:0004106 - chorismate mutase activity

References:

Modification

MOD:00046 - O-phospho-L-serine

References:

MOD:01148 - ubiquitinylated lysine

References:

Qualitative gene expression

PomGeneEx:0000019 - protein level decreased

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0002451 - inviable vegetative cell with abnormal cell shape

References:

Genotypes:

Subunit composition

PBO:0015212 - homomeric(2)

Taxonomic conservation

PBO:0011067 - conserved in bacteria

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

Protein features

IDNameInterPro nameDB name
PF01817CM_2CM_II_prokaryotPfam
PS51169CHORISMATE_MUT_3Chorismate_mutase_AroQ_eukPROSITE profiles
G3DSA:1.10.590.10:FF:000002CATH-FunFam
G3DSA:1.10.590.10CM_AroQ_sf_eucaryoticCATH-Gene3D
SSF48600Chorismate_II_sfSUPERFAMILY
PTHR21145Chorismate_mutase_AroQ_eukPANTHER
PIRSF017318Chor_mut_AroQ_euChorismate_mutase_AroQ_eukPIRSF
TIGR01802CM_pl-ystChorismate_mutase_AroQ_eukNCBIFAM

Orthologs

References / Literature

PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.
Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:25647499 - Production of CoQ10 in fission yeast by expression of genes responsible for CoQ10 biosynthesis.
Moriyama D et al. Biosci Biotechnol Biochem 2015;79(6):1026-33
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.
Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87
PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.
Strachan J et al. J Cell Sci 2023 Dec 01;136(23)
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:26412298 - A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.
Beckley JR et al. Mol Cell Proteomics 2015 Dec;14(12):3132-41