PomBase - protein coding gene - rpl14 (SPAC1805.13) - 60S ribosomal protein L14 - The Schizosaccharomyces pombe genome database

ID	Name	InterPro name	DB name
PF00467	KOW	KOW	Pfam
PF01929	Ribosomal_L14e	Ribosomal_eL14_dom	Pfam
cd23702	eL14		CDD
G3DSA:2.30.30.30:FF:000030			CATH-FunFam
G3DSA:2.30.30.30		Rib_uL2_dom2	CATH-Gene3D
G3DSA:6.10.250.2270			CATH-Gene3D
SSF50104		Translation_prot_SH3-like_sf	SUPERFAMILY
PTHR11127		Ribosomal_eL14	PANTHER

References / Literature

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.: Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.: Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:27984744 - Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs.: Joh RI et al. Mol Cell 2016 Dec 15;64(6):1088-1101
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.: Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87
PMID:33313903 - Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast.: Rubio A et al. Nucleic Acids Res 2021 Jan 11;49(1):383-399
PMID:33823663 - A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans.: Halova L et al. Open Biol 2021 Apr;11(4):200405
PMID:26404184 - High Confidence Fission Yeast SUMO Conjugates Identified by Tandem Denaturing Affinity Purification.: Nie M et al. Sci Rep 2015 Sep 25;5:14389
PMID:34496258 - Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription.: Heo DH et al. Cell Rep 2021 Sep 07;36(10):109671
PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.: Strachan J et al. J Cell Sci 2023 Dec 01;136(23)
PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.: Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105
PMID:21511999 - Comparative functional genomics of the fission yeasts.: Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:39379376 - Ribosomes hibernate on mitochondria during cellular stress.: Gemin O et al. Nat Commun 2024 Oct 08;15(1):8666
PMID:26152728 - A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast.: Mathiassen SG et al. J Biol Chem 2015 Aug 21;290(34):21141-21153
PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.: Skribbe M et al. Mol Cell 2025 Feb 19;
PMID:42129552 - SNOR promotes translation restart after dormancy.: Gluc M et al. Nature 2026 May 13;
PMID:26412298 - A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.: Beckley JR et al. Mol Cell Proteomics 2015 Dec;14(12):3132-41
PMID:20403971 - Proteomic and functional analysis of the noncanonical poly(A) polymerase Cid14.: Keller C et al. RNA 2010 Jun;16(6):1124-9
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.: Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:36423630 - Chromatin localization of nucleophosmin organizes ribosome biogenesis.: Ugolini I et al. Mol Cell 2022 Dec 01;82(23):4443-4457.e9
PMID:39705284 - Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast.: Bérard M et al. PLoS Biol 2024 Dec 20;22(12):e3002963
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).: Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.: Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.: Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:30321377 - Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome.: Telekawa C et al. Nucleic Acids Res 2018 Nov 30;46(21):11169-11183

protein coding gene - rpl14 (SPAC1805.13) - 60S ribosomal protein L14

Gene summary

Annotation

GO biological process

GO:0002181 - cytoplasmic translation

GO:0042273 - ribosomal large subunit biogenesis

GO cellular component

GO:0005737 - cytoplasm

GO:0005829 - cytosol

GO:0022625 - cytosolic large ribosomal subunit

GO:0005634 - nucleus

GO:0030684 - preribosome

GO molecular function

GO:0003723 - RNA binding

GO:0003735 - structural constituent of ribosome

Modification

MOD:00046 - O-phospho-L-serine

MOD:00048 - O4'-phospho-L-tyrosine

MOD:01149 - sumoylated lysine

MOD:01148 - ubiquitinylated lysine

Qualitative gene expression

PomGeneEx:0000019 - protein level decreased

PomGeneEx:0000027 - ribosomal density decreased

PomGeneEx:0000012 - RNA level decreased

Quantitative gene expression

PBO:0006310 - protein level

PBO:0011963 - RNA level

Single locus phenotype

FYPO:0002060 - viable vegetative cell population

FYPO:0002177 - viable vegetative cell with normal cell morphology

Taxonomic conservation

PBO:0011072 - conserved in archaea

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

Protein features

Orthologs

References / Literature