protein coding gene - pat10 (SPAC18B11.08c) - ER membrane chaperone for multipass membrane proteins, PAT complex subunit (asterix), Pat10

Gene summary

Standard name

pat10

Systematic ID

SPAC18B11.08c

Product

ER membrane chaperone for multipass membrane proteins, PAT complex subunit (asterix), Pat10

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

Q09714

ORFeome ID

42/42C09

Characterisation status

biological role inferred

Feature type

mRNA gene

Genomic location

chromosome I: 304412..305168 forward strand

Annotation

Protein features

Orthologs

• WDR83OS (HGNC:30203) Homo sapiens
• pat10 (SJAG_05414) Schizosaccharomyces japonicus
• YPR063C Saccharomyces cerevisiae

References / Literature

PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.

Rodríguez-López M et al. Elife 2023 Oct 03;12

InterPro:IPR005351 - Unknown title

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36

GO_REF:0000050 - Manual transfer of GO annotation data to genes by curator judgment of sequence model

PMID:11152613 - Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes.

Krogh A et al. J Mol Biol 2001 Jan 19;305(3):567-80

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:33109728 - High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library.

Varberg JM et al. G3 (Bethesda) 2020 Dec 03;10(12):4649-4663

PMID:34250083 - Barcode sequencing and a high-throughput assay for chronological lifespan uncover ageing-associated genes in fission yeast.

Romila CA et al. Microb Cell 2021 Jul 05;8(7):146-160

PMID:32814900 - An intramembrane chaperone complex facilitates membrane protein biogenesis.

Chitwood PJ et al. Nature 2020 Aug;584(7822):630-634

PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.

Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105

PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs

PMID:29259000 - Genes Important for Schizosaccharomyces pombe Meiosis Identified Through a Functional Genomics Screen.

Blyth J et al. Genetics 2018 Feb;208(2):589-603

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.

Skribbe M et al. Mol Cell 2025 Feb 19;

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:26896847 - Ensembl comparative genomics resources.

Herrero J et al. Database (Oxford) 2016;2016

PMID:27984744 - Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs.

Joh RI et al. Mol Cell 2016 Dec 15;64(6):1088-1101

PMID:29735745 - Control of mitotic chromosome condensation by the fission yeast transcription factor Zas1.

Schiklenk C et al. J Cell Biol 2018 Jul 02;217(7):2383-2401

PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.

Strachan J et al. J Cell Sci 2023 Dec 01;136(23)