protein coding gene - tsr3 (SPAC1F3.04c) - SSU-rRNA maturation protein Tsr3

Gene summary

Standard name: tsr3
Systematic ID: SPAC1F3.04c
Product: SSU-rRNA maturation protein Tsr3
Organism: Schizosaccharomyces pombe (fission yeast)
UniProt ID: Q10409
ORFeome ID: 14/14G04
Characterisation status: biological role inferred
Feature type: mRNA gene
Genomic location: chromosome I: 621054..622220 reverse strand

Annotation

GO biological process

GO:0000455 - enzyme-directed rRNA pseudouridine synthesis

References:

GO_REF:0000104

GO:0030490 - maturation of SSU-rRNA

References:

GO_REF:0000033

GO cellular component

GO:0005737 - cytoplasm

References:

GO_REF:0000024

GO:0005634 - nucleus

References:

GO_REF:0000024

GO molecular function

GO:0046872 - metal ion binding

References:

GO_REF:0000050

GO:0106388 - rRNA small subunit aminocarboxypropyltransferase activity

References:

GO_REF:0000116

GO:1904047 - S-adenosyl-L-methionine binding

References:

GO_REF:0000104

Quantitative gene expression

PBO:0006310 - protein level

References:

PMID:23101633

PBO:0011963 - RNA level

References:

PMID:23101633

Single locus phenotype

FYPO:0002060 - viable vegetative cell population

References:

PMID:20519959

Genotypes:

tsr3delta

Taxonomic conservation

PBO:0011072 - conserved in archaea

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

ID	Name	InterPro name	DB name
PF04034	Ribo_biogen_C	Tsr3_C	PFAM
PF04068	Fer4_RLI	RNaseL-inhib-like_metal-bd_dom	PFAM
PTHR20426	RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG	Tsr3-like	PANTHER
Coil	Coil		COILS
MF_01116	TSR3	Tsr3-like	HAMAP
mobidb-lite-Disorder	disorder_prediction		MOBIDB-Disorder
mobidb-lite-Polar	disorder_prediction		MOBIDB-Polar
mobidb-lite-Polyampholyte	disorder_prediction		MOBIDB-Polyampholyte
NF002621	PRK02287.1		NCBIFAM

Orthologs

TSR3 (HGNC:14175) Homo sapiens
tsr3 (SJAG_03755) Schizosaccharomyces japonicus
TSR3 (YOR006C) Saccharomyces cerevisiae

References / Literature

GO_REF:0000116 - Automatic Gene Ontology annotation based on Rhea mapping.
PMID:20519959 - S. pombe genome deletion project: an update.: Spirek M et al. Cell Cycle 2010 Jun 15;9(12):2399-402
PMID:21511999 - Comparative functional genomics of the fission yeasts.: Rhind N et al. Science 2011 May 20;332(6032):930-6
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
GO_REF:0000104 - Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.: Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:26670050 - Regulation of mRNA Levels by Decay-Promoting Introns that Recruit the Exosome Specificity Factor Mmi1.: Kilchert C et al. Cell Rep 2015 Dec 22;13(11):2504-2515
GO_REF:0000033 - Annotation inferences using phylogenetic trees
GO_REF:0000050 - Manual transfer of GO annotation data to genes by curator judgment of sequence model