protein coding gene - cdc22 (SPAC1F7.05) - ribonucleoside reductase large subunit Cdc22

Gene summary

Standard name

cdc22

Systematic ID

SPAC1F7.05

Product

ribonucleoside reductase large subunit Cdc22

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

P36602

ORFeome ID

47/47B09

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome I: 4226970..4229989 forward strand

Annotation

Protein features

Orthologs

• RRM1 (HGNC:10451) Homo sapiens
• cdc22 (SJAG_04665) Schizosaccharomyces japonicus
• RNR1 (YER070W) Saccharomyces cerevisiae
• RNR3 (YIL066C) Saccharomyces cerevisiae

References / Literature

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PMID:31064814 - Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast.

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PMID:34496258 - Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription.

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PMID:9950674 - Liz1p, a novel fission yeast membrane protein, is required for normal cell division when ribonucleotide reductase is inhibited.

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PMID:6943408 - Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe.

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PMID:7768995 - The Schizosaccharomyces pombe hus5 gene encodes a ubiquitin conjugating enzyme required for normal mitosis.

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PMID:31626996 - Multiplexed proteome profiling of carbon source perturbations in two yeast species with SL-SP3-TMT.

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PMID:11313455 - Fission yeast Rad17 associates with chromatin in response to aberrant genomic structures.

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PMID:12455694 - mcl1+, the Schizosaccharomyces pombe homologue of CTF4, is important for chromosome replication, cohesion, and segregation.

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PMID:8319772 - In vivo phosphorylation, mitotic behavior, and nuclear binding of the catalytic subunit of DNA polymerase alpha in fission yeast.

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PMID:11523776 - Sna41goa1, a novel mutation causing G1/S arrest in fission yeast, is defective in a CDC45 homolog and interacts genetically with polalpha.

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PMID:8657126 - Cig2, a B-type cyclin, promotes the onset of S in Schizosaccharomyces pombe.

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PMID:9153313 - Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: a gene required for the DNA damage checkpoint but not the replication checkpoint.

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