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protein coding gene - cdc15 (SPAC20G8.05c) - F-BAR domain protein Cdc15

Gene summary

Standard name
cdc15
Systematic ID
SPAC20G8.05c
Product
F-BAR domain protein Cdc15
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
Q09822
ORFeome ID
30/30A01
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome I: 1399200..1402936 reverse strand

Annotation

Comment

PBO:0024819 - promoter contains PCB

References:

Disease association

MONDO:0011174 - hyperzincemia with functional zinc depletion

References:

MONDO:0011462 - pyogenic arthritis-pyoderma gangrenosum-acne syndrome

References:

GO biological process

GO:0072583 - clathrin-dependent endocytosis

References:

GO:0061171 - establishment of bipolar cell polarity

References:

GO:1903475 - mitotic actomyosin contractile ring assembly

References:

GO:0097753 - membrane bending

References:

GO cellular component

GO:0030479 - actin cortical patch

References:

GO:0032153 - cell division site

References:

GO:0051286 - cell tip

References:

GO:0005737 - cytoplasm

References:

GO:0009898 - cytoplasmic side of plasma membrane

References:

GO:0043332 - mating projection tip

References:

GO:0071341 - medial cortical node

References:

GO:0032178 - medial membrane band

References:

GO:0110085 - mitotic actomyosin contractile ring

References:

GO:0120104 - mitotic actomyosin contractile ring, proximal layer

References:

GO molecular function

GO:0106006 - cytoskeletal protein-membrane anchor activity

References:

GO:0005543 - phospholipid binding

References:

GO:0005515 - protein binding

References:

Modification

MOD:00046 - O-phospho-L-serine

References:

MOD:00047 - O-phospho-L-threonine

References:

MOD:00048 - O4'-phospho-L-tyrosine

References:

MOD:00696 - phosphorylated residue

References:

MOD:01148 - ubiquitinylated lysine

References:

Multi-locus phenotype

FYPO:0003890 - abnormal primary cell septum biogenesis

References:

Genotypes:

FYPO:0000117 - abnormal septum assembly

References:

Genotypes:

FYPO:0002023 - abnormal septum morphology during vegetative growth

References:

Genotypes:

FYPO:0005503 - abnormally monopolar protein localization to cell tip

References:

Genotypes:

FYPO:0001009 - abolished actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0002998 - abolished actomyosin contractile ring assembly, clumped medial cortical nodes

References:

Genotypes:

FYPO:0004481 - abolished cell population growth at high temperature

References:

Genotypes:

FYPO:0002561 - abolished protein localization to actomyosin contractile ring

References:

Genotypes:

FYPO:0003371 - abolished protein localization to actomyosin contractile ring, with protein mislocalized to cytoplasm

References:

Genotypes:

FYPO:0003919 - abolished protein localization to medial cortical node

References:

Genotypes:

FYPO:0005289 - actomyosin contractile ring sliding

References:

Genotypes:

FYPO:0000082 - decreased cell population growth at high temperature

References:

Genotypes:

FYPO:0000080 - decreased cell population growth at low temperature

References:

Genotypes:

FYPO:0001407 - decreased cell population growth on glucose carbon source

References:

Genotypes:

FYPO:0003331 - decreased protein kinase activity during mitotic interphase

References:

Genotypes:

FYPO:0004085 - decreased vegetative cell growth

References:

Genotypes:

FYPO:0001355 - decreased vegetative cell population growth

References:

Genotypes:

FYPO:0003946 - delayed onset of protein localization to cell division site

References:

Genotypes:

FYPO:0002021 - dispersed actin cortical patch localization during vegetative growth

References:

Genotypes:

FYPO:0001253 - elongated multinucleate multiseptate vegetative cell, single septa between nuclei

References:

Genotypes:

FYPO:0003532 - increased monopolar index

References:

Genotypes:

FYPO:0002059 - inviable cell population

References:

Genotypes:

FYPO:0004104 - inviable spherical vegetative cell

References:

Genotypes:

FYPO:0006262 - inviable stubby binucleate vegetative cell

References:

Genotypes:

FYPO:0003989 - inviable stubby mononucleate vegetative cell

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0002273 - inviable vegetative cell with abnormal cell morphology

References:

Genotypes:

FYPO:0000061 - multinucleate vegetative cell

References:

Genotypes:

FYPO:0002062 - normal cell growth

References:

Genotypes:

FYPO:0000674 - normal cell population growth at high temperature

References:

Genotypes:

FYPO:0002141 - normal cell population growth at low temperature

References:

Genotypes:

FYPO:0001164 - normal growth on glucose carbon source

References:

Genotypes:

FYPO:0003332 - normal protein kinase activity during mitotic interphase

References:

Genotypes:

FYPO:0002999 - normal protein localization to medial cortical node

References:

Genotypes:

FYPO:0002967 - normal protein localization to mitotic spindle pole body

References:

Genotypes:

FYPO:0001357 - normal vegetative cell population growth

References:

Genotypes:

FYPO:0007393 - septum mislocalized to cell tip

References:

Genotypes:

FYPO:0004257 - swollen multinucleate vegetative cell

References:

Genotypes:

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

Qualitative gene expression

PomGeneEx:0000019 - protein level decreased

References:

PomGeneEx:0000026 - ribosomal density increased

References:

PomGeneEx:0000012 - RNA level decreased

References:

PomGeneEx:0000017 - RNA level fluctuates

References:

PomGeneEx:0000011 - RNA level increased

References:

PomGeneEx:0000014 - RNA present

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002373 - abnormal actin cortical patch localization during mitosis

References:

Genotypes:

FYPO:0000190 - abnormal actin cortical patch localization during vegetative growth

References:

Genotypes:

FYPO:0000161 - abnormal actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0000164 - abnormal cell separation after cytokinesis

References:

Genotypes:

FYPO:0002872 - abnormal endoplasmic reticulum localization

References:

Genotypes:

FYPO:0000059 - abnormal mitotic cell cycle

References:

Genotypes:

FYPO:0001401 - abnormal protein localization to cell division site

References:

Genotypes:

FYPO:0007405 - abnormal protein localization to medial cortex, with protein distributed in cell cortex, during vegetative growth

References:

Genotypes:

FYPO:0000026 - abnormal vegetative cell polarity

References:

Genotypes:

FYPO:0001009 - abolished actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0003838 - abolished actomyosin contractile ring contraction

References:

Genotypes:

FYPO:0004481 - abolished cell population growth at high temperature

References:

Genotypes:

FYPO:0001018 - abolished NETO

References:

Genotypes:

FYPO:0002561 - abolished protein localization to actomyosin contractile ring

References:

Genotypes:

FYPO:0003371 - abolished protein localization to actomyosin contractile ring, with protein mislocalized to cytoplasm

References:

Genotypes:

FYPO:0001880 - abolished protein localization to cell division site

References:

Genotypes:

FYPO:0007178 - abolished protein localization to medial cortex during mitosis

References:

Genotypes:

FYPO:0007177 - abolished protein localization to medial cortex during mitotic interphase

References:

Genotypes:

FYPO:0002555 - abolished protein localization to medial cortex during vegetative growth

References:

Genotypes:

FYPO:0000705 - abolished protein-protein interaction

References:

Genotypes:

FYPO:0001008 - actomyosin contractile ring absent

References:

Genotypes:

FYPO:0005289 - actomyosin contractile ring sliding

References:

Genotypes:

FYPO:0006939 - asymmetric actomyosin contractile ring contraction

References:

Genotypes:

FYPO:0002050 - branched elongated multinucleate aseptate vegetative cell

References:

Genotypes:

FYPO:0004594 - branched, elongated, septated cell

References:

Genotypes:

FYPO:0000082 - decreased cell population growth at high temperature

References:

Genotypes:

FYPO:0000422 - decreased endocytosis during vegetative growth

References:

Genotypes:

FYPO:0005307 - decreased phospholipid binding

References:

Genotypes:

FYPO:0006120 - decreased protein localization to actin cortical patch

References:

Genotypes:

FYPO:0002699 - decreased protein localization to actomyosin contractile ring

References:

Genotypes:

FYPO:0005467 - decreased protein localization to actomyosin contractile ring during mitosis

References:

Genotypes:

FYPO:0002869 - decreased protein localization to cell division site

References:

Genotypes:

FYPO:0001586 - decreased protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0006326 - decreased protein localization to medial cortical node

References:

Genotypes:

FYPO:0001838 - decreased protein phosphorylation during vegetative growth

References:

Genotypes:

FYPO:0001645 - decreased protein-protein interaction

References:

Genotypes:

FYPO:0003339 - decreased rate of actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0001365 - decreased rate of actomyosin contractile ring contraction

References:

Genotypes:

FYPO:0001355 - decreased vegetative cell population growth

References:

Genotypes:

FYPO:0000729 - delayed onset of actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0006831 - delayed onset of primary cell septum biogenesis

References:

Genotypes:

FYPO:0003342 - elongated multinucleate cell

References:

Genotypes:

FYPO:0003343 - elongated multinucleate multiseptate cell, single septa between nuclei

References:

Genotypes:

FYPO:0001253 - elongated multinucleate multiseptate vegetative cell, single septa between nuclei

References:

Genotypes:

FYPO:0000133 - elongated multinucleate vegetative cell

References:

Genotypes:

FYPO:0005903 - incomplete actomyosin contractile ring contraction

References:

Genotypes:

FYPO:0005840 - incomplete, asymmetric septum

References:

Genotypes:

FYPO:0003533 - increased bipolar index

References:

Genotypes:

FYPO:0005543 - increased duration of actomyosin contractile ring contraction

References:

Genotypes:

FYPO:0003532 - increased monopolar index

References:

Genotypes:

FYPO:0004854 - increased protein localization to actomyosin contractile ring

References:

Genotypes:

FYPO:0009061 - increased protein localization to cell cortex during mitotic interphase

References:

Genotypes:

FYPO:0009059 - increased protein localization to cell cortex during vegetative growth

References:

Genotypes:

FYPO:0008075 - increased protein localization to cell cortex of cell tip during vegetative growth

References:

Genotypes:

FYPO:0002852 - increased protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0004977 - increased protein localization to new cell tip

References:

Genotypes:

FYPO:0002127 - increased protein localization to plasma membrane during vegetative growth

References:

Genotypes:

FYPO:0006186 - increased rate of actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0006897 - increased rate of actomyosin contractile ring contraction

References:

Genotypes:

FYPO:0000650 - increased septation index

References:

Genotypes:

FYPO:0000316 - inviable after spore germination

References:

Genotypes:

FYPO:0000314 - inviable after spore germination with elongated germ tube

References:

Genotypes:

FYPO:0003825 - inviable binucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition before cell separation

References:

Genotypes:

FYPO:0002059 - inviable cell population

References:

Genotypes:

FYPO:0002024 - inviable elongated multinucleate aseptate vegetative cell

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0001369 - mislocalized actomyosin contractile ring

References:

Genotypes:

FYPO:0007179 - mislocalized protein distributed in cell cortex during mitotic interphase

References:

Genotypes:

FYPO:0004293 - mislocalized septum

References:

Genotypes:

FYPO:0002424 - normal actin cortical patch localization during mitotic interphase

References:

Genotypes:

FYPO:0001368 - normal actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0000674 - normal cell population growth at high temperature

References:

Genotypes:

FYPO:0002141 - normal cell population growth at low temperature

References:

Genotypes:

FYPO:0007528 - normal membrane lipid binding

References:

Genotypes:

FYPO:0003075 - normal protein kinase activity

References:

Genotypes:

FYPO:0000833 - normal protein level during vegetative growth

References:

Genotypes:

FYPO:0002559 - normal protein localization to actomyosin contractile ring

References:

Genotypes:

FYPO:0006635 - normal protein localization to cell tip during mitotic interphase

References:

Genotypes:

FYPO:0001587 - normal protein localization to cell tip during vegetative growth

References:

Genotypes:

FYPO:0003316 - normal protein localization to growing cell tip

References:

Genotypes:

FYPO:0002999 - normal protein localization to medial cortical node

References:

Genotypes:

FYPO:0002967 - normal protein localization to mitotic spindle pole body

References:

Genotypes:

FYPO:0002674 - normal protein localization to plasma membrane

References:

Genotypes:

FYPO:0005221 - normal protein oligomerization

References:

Genotypes:

FYPO:0004422 - normal protein phosphorylation

References:

Genotypes:

FYPO:0006187 - normal rate of actomyosin contractile ring assembly

References:

Genotypes:

FYPO:0001903 - normal septation index

References:

Genotypes:

FYPO:0002085 - normal vegetative cell growth

References:

Genotypes:

FYPO:0001357 - normal vegetative cell population growth

References:

Genotypes:

FYPO:0001904 - premature actomyosin contractile ring disassembly

References:

Genotypes:

FYPO:0002874 - premature protein localization to medial cortex during vegetative growth

References:

Genotypes:

FYPO:0000107 - sensitive to latrunculin A

References:

Genotypes:

FYPO:0002080 - sensitive to TPCK

References:

Genotypes:

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

FYPO:0002177 - viable vegetative cell with normal cell morphology

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

Protein features

IDNameInterPro nameDB name
PF00018SH3_1SH3_domainPFAM
PF00611FCHFCH_domPFAM
cd07651F-BAR_PombeCdc15_likeCDD
cd00174SH3CDD
PS50002SH3SH3_domainPROSITE_PROFILES
PS51741F_BARF_BAR_domPROSITE_PROFILES
SM00055fch_2FCH_domSMART
SM00326SH3_2SH3_domainSMART
PR00452SH3DOMAINSH3_domainPRINTS
G3DSA:2.30.30.40:FF:000164FUNFAM
SSF50044SH3-domainSH3-like_dom_sfSUPERFAMILY
SSF103657BAR/IMD domain-likeAH/BAR_dom_sfSUPERFAMILY
G3DSA:2.30.30.40SH3 DomainsGENE3D
G3DSA:1.20.1270.60Arfaptin homology (AH) domain/BAR domainAH/BAR_dom_sfGENE3D
PTHR23065PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1PANTHER
CoilCoilCOILS
mobidb-lite-Disorderdisorder_predictionMOBIDB-Disorder
mobidb-lite-Low-complexitydisorder_predictionMOBIDB-Low-complexity
mobidb-lite-Polardisorder_predictionMOBIDB-Polar
mobidb-lite-Polyampholytedisorder_predictionMOBIDB-Polyampholyte

Orthologs

References / Literature

PMID:37531259 - Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins.
Willet AH et al. Mol Biol Cell 2023 Oct 01;34(11):br17
PMID:40114852 - Characterization and comparison of Schizosaccharomyces pombe cdc15 temperature-sensitive mutants.
Turner LA et al. MicroPubl Biol 2025;2025
PMID:958201 - Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe.
Nurse P et al. Mol Gen Genet 1976 Jul 23;146(2):167-78
PMID:15265986 - The Clp1p/Flp1p phosphatase ensures completion of cytokinesis in response to minor perturbation of the cell division machinery in Schizosaccharomyces pombe.
Mishra M et al. J Cell Sci 2004 Aug 01;117(Pt 17):3897-910
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:30709916 - A Cdc42 GEF, Gef1, through endocytosis organizes F-BAR Cdc15 along the actomyosin ring and promotes concentric furrowing.
Onwubiko UN et al. J Cell Sci 2019 Feb 28;132(5)
PMID:39476757 - Characterization of Ksg1 protein kinase-dependent phosphoproteome in the fission yeast S. pombe.
Cipak L et al. Biochem Biophys Res Commun 2024 Oct 25;736:150895
PMID:16772338 - The fission yeast Chs2 protein interacts with the type-II myosin Myo3p and is required for the integrity of the actomyosin ring.
Martín-García R et al. J Cell Sci 2006 Jul 01;119(Pt 13):2768-79
PMID:26132084 - Cooperation between Paxillin-like Protein Pxl1 and Glucan Synthase Bgs1 Is Essential for Actomyosin Ring Stability and Septum Formation in Fission Yeast.
Cortés JC et al. PLoS Genet 2015 Jul;11(7):e1005358
PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.
Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7
PMID:25159149 - Contractile ring stability in S. pombe depends on F-BAR protein Cdc15p and Bgs1p transport from the Golgi complex.
Arasada R et al. Cell Rep 2014 Sep 11;8(5):1533-44
PMID:10805785 - Sid4p is required to localize components of the septation initiation pathway to the spindle pole body in fission yeast.
Chang L et al. Proc Natl Acad Sci U S A 2000 May 09;97(10):5249-54
PMID:34296454 - The TOR-dependent phosphoproteome and regulation of cellular protein synthesis.
Mak T et al. EMBO J 2021 Aug 16;40(16):e107911
PMID:33313903 - Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast.
Rubio A et al. Nucleic Acids Res 2021 Jan 11;49(1):383-399
PMID:19139265 - The SH3 domains of two PCH family members cooperate in assembly of the Schizosaccharomyces pombe contractile ring.
Roberts-Galbraith RH et al. J Cell Biol 2009 Jan 12;184(1):113-27
PMID:37746062 - Polarity kinases that phosphorylate F-BAR protein Cdc15 have unique localization patterns during cytokinesis and contributions to preventing tip septation in Schizosaccharomyces pombe .
Igarashi MG et al. MicroPubl Biol 2023;2023
PMID:9105045 - cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin.
Chang F et al. J Cell Biol 1997 Apr 07;137(1):169-82
PMID:9649519 - Isolation and characterization of new fission yeast cytokinesis mutants.
Balasubramanian MK et al. Genetics 1998 Jul;149(3):1265-75
PMID:19075108 - Assembly of normal actomyosin rings in the absence of Mid1p and cortical nodes in fission yeast.
Huang Y et al. J Cell Biol 2008 Dec 15;183(6):979-88
PMID:27984725 - CDK Substrate Phosphorylation and Ordering the Cell Cycle.
Swaffer MP et al. Cell 2016 Dec 15;167(7):1750-1761.e16
PMID:1527180 - Genetic interactions in the control of septation in Schizosaccharomyces pombe.
Marks J et al. J Cell Sci 1992 Apr;101 ( Pt 4):801-8
PMID:32848252 - Closed mitosis requires local disassembly of the nuclear envelope.
Dey G et al. Nature 2020 Sep;585(7823):119-123
PMID:21712547 - Mitotic substrates of the kinase aurora with roles in chromatin regulation identified through quantitative phosphoproteomics of fission yeast.
Koch A et al. Sci Signal 2011 Jun 28;4(179):rs6
PMID:22891259 - Fission yeast Ags1 confers the essential septum strength needed for safe gradual cell abscission.
Cortés JC et al. J Cell Biol 2012 Aug 20;198(4):637-56
PMID:18257517 - Phosphoproteome analysis of fission yeast.
Wilson-Grady JT et al. J Proteome Res 2008 Mar;7(3):1088-97
PMID:25688133 - The F-BAR Cdc15 promotes contractile ring formation through the direct recruitment of the formin Cdc12.
Willet AH et al. J Cell Biol 2015 Feb 16;208(4):391-9
PMID:35108037 - Fission yeast paxillin contains two Cdc15 binding motifs for robust recruitment to the cytokinetic ring.
Snider CE et al. Mol Biol Cell 2022 Apr 01;33(4):br4
PMID:8834798 - Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring.
Chang F et al. J Cell Sci 1996 Jan;109 ( Pt 1):131-42
PMID:20231270 - Schizosaccharomyces pombe Dss1p is a DNA damage checkpoint protein that recruits Rad24p, Cdc25p, and Rae1p to DNA double-strand breaks.
Selvanathan SP et al. J Biol Chem 2010 May 07;285(19):14122-33
PMID:28784611 - Phosphoinositide-mediated ring anchoring resists perpendicular forces to promote medial cytokinesis.
Snider CE et al. J Cell Biol 2017 Oct 02;216(10):3041-3050
PMID:20876564 - Antagonistic roles of PP2A-Pab1 and Etd1 in the control of cytokinesis in fission yeast.
Lahoz A et al. Genetics 2010 Dec;186(4):1261-70
PMID:30853434 - NDR Kinase Sid2 Drives Anillin-like Mid1 from the Membrane to Promote Cytokinesis and Medial Division Site Placement.
Willet AH et al. Curr Biol 2019 Mar 18;29(6):1055-1063.e2
PMID:25825517 - A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast.
Dudin O et al. J Cell Biol 2015 Mar 30;208(7):897-911
PMID:31509478 - The intrinsically disordered region of the cytokinetic F-BAR protein Cdc15 performs a unique essential function in maintenance of cytokinetic ring integrity.
Mangione MC et al. Mol Biol Cell 2019 Oct 15;30(22):2790-2801
PMID:34133210 - Cdk1 phosphorylation of fission yeast paxillin inhibits its cytokinetic ring localization.
Mangione MC et al. Mol Biol Cell 2021 Aug 15;32(17):1534-1544
PMID:10503548 - Analysis of the cps1 gene provides evidence for a septation checkpoint in Schizosaccharomyces pombe.
Le Goff X et al. Mol Gen Genet 1999 Aug;262(1):163-72
PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.
Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87
PMID:10769201 - The S. pombe orthologue of the S. cerevisiae mob1 gene is essential and functions in signalling the onset of septum formation.
Salimova E et al. J Cell Sci 2000 May;113 ( Pt 10):1695-704
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:18256290 - Schizosaccharomyces pombe Pxl1 is a paxillin homologue that modulates Rho1 activity and participates in cytokinesis.
Pinar M et al. Mol Biol Cell 2008 Apr;19(4):1727-38
PMID:11694585 - Interactions among a fimbrin, a capping protein, and an actin-depolymerizing factor in organization of the fission yeast actin cytoskeleton.
Nakano K et al. Mol Biol Cell 2001 Nov;12(11):3515-26
PMID:18272786 - Pxl1p, a paxillin-related protein, stabilizes the actomyosin ring during cytokinesis in fission yeast.
Ge W et al. Mol Biol Cell 2008 Apr;19(4):1680-92
PMID:25977474 - A role for F-BAR protein Rga7p during cytokinesis in S. pombe.
Arasada R et al. J Cell Sci 2015 Jul 01;128(13):2259-68
PMID:7634333 - The S. pombe cdc15 gene is a key element in the reorganization of F-actin at mitosis.
Fankhauser C et al. Cell 1995 Aug 11;82(3):435-44
PMID:25428987 - The Cdc15 and Imp2 SH3 domains cooperatively scaffold a network of proteins that redundantly ensure efficient cell division in fission yeast.
Ren L et al. Mol Biol Cell 2015 Jan 15;26(2):256-69
PMID:9649518 - A screen for genes involved in the anaphase proteolytic pathway identifies tsm1(+), a novel Schizosaccharomyces pombe gene important for microtubule integrity.
Grishchuk EL et al. Genetics 1998 Jul;149(3):1251-64
PMID:22918943 - Anillin-related protein Mid1p coordinates the assembly of the cytokinetic contractile ring in fission yeast.
Saha S et al. Mol Biol Cell 2012 Oct;23(20):3982-92
PMID:15302827 - The forkhead transcription factor Fkh2 regulates the cell division cycle of Schizosaccharomyces pombe.
Bulmer R et al. Eukaryot Cell 2004 Aug;3(4):944-54
PMID:36287824 - Imp2p forms actin-dependent clusters and imparts stiffness to the contractile ring.
Bellingham-Johnstun K et al. Mol Biol Cell 2022 Dec 01;33(14):ar145
PMID:28218250 - Chromatin remodeller Fun30 Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.
Lee J et al. Nat Commun 2017 Feb 20;8:14527
PMID:8039497 - The cdc7 protein kinase is a dosage dependent regulator of septum formation in fission yeast.
Fankhauser C et al. EMBO J 1994 Jul 01;13(13):3011-9
PMID:32101481 - DYRK kinase Pom1 drives F-BAR protein Cdc15 from the membrane to promote medial division.
Bhattacharjee R et al. Mol Biol Cell 2020 Apr 15;31(9):917-929
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:11870208 - F-actin ring formation and the role of F-actin cables in the fission yeast Schizosaccharomyces pombe.
Arai R et al. J Cell Sci 2002 Mar 01;115(Pt 5):887-98
PMID:18378776 - The Clp1/Cdc14 phosphatase contributes to the robustness of cytokinesis by association with anillin-related Mid1.
Clifford DM et al. J Cell Biol 2008 Apr 07;181(1):79-88
PMID:22347452 - The SET domain protein, Set3p, promotes the reliable execution of cytokinesis in Schizosaccharomyces pombe.
Rentas S et al. PLoS One 2012;7(2):e31224
PMID:31217286 - Increasing ergosterol levels delays formin-dependent assembly of F-actin cables and disrupts division plane positioning in fission yeast.
Arbizzani F et al. J Cell Sci 2019 Jul 01;132(13)
PMID:22573890 - Fission yeast Cyk3p is a transglutaminase-like protein that participates in cytokinesis and cell morphogenesis.
Pollard LW et al. Mol Biol Cell 2012 Jul;23(13):2433-44
PMID:23297348 - Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase.
Chen JS et al. Mol Cell Proteomics 2013 May;12(5):1074-86
PMID:18184749 - The actomyosin ring recruits early secretory compartments to the division site in fission yeast.
Vjestica A et al. Mol Biol Cell 2008 Mar;19(3):1125-38
PMID:11854409 - The multiprotein exocyst complex is essential for cell separation in Schizosaccharomyces pombe.
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PMID:36749320 - Multiple polarity kinases inhibit phase separation of F-BAR protein Cdc15 and antagonize cytokinetic ring assembly in fission yeast.
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