protein coding gene - cdc15 (SPAC20G8.05c) - F-BAR domain protein Cdc15

Gene summary

Standard name

cdc15

Systematic ID

SPAC20G8.05c

Product

F-BAR domain protein Cdc15

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

Q09822

ORFeome ID

30/30A01

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome I: 1399200..1402936 reverse strand

Annotation

Protein features

Orthologs

• PSTPIP1 (HGNC:9580) Homo sapiens
• PSTPIP2 (HGNC:9581) Homo sapiens
• cdc15 (SJAG_03596) Schizosaccharomyces japonicus
• HOF1 (YMR032W) Saccharomyces cerevisiae

References / Literature

PMID:22891259 - Fission yeast Ags1 confers the essential septum strength needed for safe gradual cell abscission.

Cortés JC et al. J Cell Biol 2012 Aug 20;198(4):637-56

PMID:27298342 - Identification of S-phase DNA damage-response targets in fission yeast reveals conservation of damage-response networks.

Willis NA et al. Proc Natl Acad Sci U S A 2016 Jun 28;113(26):E3676-85

PMID:22905165 - The integrity of the cytokinesis machinery under stress conditions requires the glucan synthase Bgs1p and its regulator Cfh3p.

Sharifmoghadam MR et al. PLoS One 2012;7(8):e42726

PMID:30044717 - Roles of the fission yeast UNC-13/Munc13 protein Ync13 in late stages of cytokinesis.

Zhu YH et al. Mol Biol Cell 2018 Sep 15;29(19):2259-2279

PMID:9105045 - cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin.

Chang F et al. J Cell Biol 1997 Apr 07;137(1):169-82

PMID:1527180 - Genetic interactions in the control of septation in Schizosaccharomyces pombe.

Marks J et al. J Cell Sci 1992 Apr;101 ( Pt 4):801-8

PMID:34133210 - Cdk1 phosphorylation of fission yeast paxillin inhibits its cytokinetic ring localization.

Mangione MC et al. Mol Biol Cell 2021 Aug 15;32(17):1534-1544

PMID:33496728 - Molecular organization of cytokinesis node predicts the constriction rate of the contractile ring.

Bellingham-Johnstun K et al. J Cell Biol 2021 Mar 01;220(3)

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:30709916 - A Cdc42 GEF, Gef1, through endocytosis organizes F-BAR Cdc15 along the actomyosin ring and promotes concentric furrowing.

Onwubiko UN et al. J Cell Sci 2019 Feb 28;132(5)

PMID:9203579 - The Spg1p GTPase is an essential, dosage-dependent inducer of septum formation in Schizosaccharomyces pombe.

Schmidt S et al. Genes Dev 1997 Jun 15;11(12):1519-34

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:11694585 - Interactions among a fimbrin, a capping protein, and an actin-depolymerizing factor in organization of the fission yeast actin cytoskeleton.

Nakano K et al. Mol Biol Cell 2001 Nov;12(11):3515-26

PMID:18184749 - The actomyosin ring recruits early secretory compartments to the division site in fission yeast.

Vjestica A et al. Mol Biol Cell 2008 Mar;19(3):1125-38

PMID:15265986 - The Clp1p/Flp1p phosphatase ensures completion of cytokinesis in response to minor perturbation of the cell division machinery in Schizosaccharomyces pombe.

Mishra M et al. J Cell Sci 2004 Aug 01;117(Pt 17):3897-910

PMID:25052092 - F-BAR domain protein Rga7 collaborates with Cdc15 and Imp2 to ensure proper cytokinesis in fission yeast.

Martín-García R et al. J Cell Sci 2014 Oct 01;127(Pt 19):4146-58

PMID:18378776 - The Clp1/Cdc14 phosphatase contributes to the robustness of cytokinesis by association with anillin-related Mid1.

Clifford DM et al. J Cell Biol 2008 Apr 07;181(1):79-88

PMID:27749909 - A New Membrane Protein Sbg1 Links the Contractile Ring Apparatus and Septum Synthesis Machinery in Fission Yeast.

Sethi K et al. PLoS Genet 2016 Oct;12(10):e1006383

PMID:16772338 - The fission yeast Chs2 protein interacts with the type-II myosin Myo3p and is required for the integrity of the actomyosin ring.

Martín-García R et al. J Cell Sci 2006 Jul 01;119(Pt 13):2768-79

PMID:20231270 - Schizosaccharomyces pombe Dss1p is a DNA damage checkpoint protein that recruits Rad24p, Cdc25p, and Rae1p to DNA double-strand breaks.

Selvanathan SP et al. J Biol Chem 2010 May 07;285(19):14122-33

PMID:31217286 - Increasing ergosterol levels delays formin-dependent assembly of F-actin cables and disrupts division plane positioning in fission yeast.

Arbizzani F et al. J Cell Sci 2019 Jul 01;132(13)

PMID:18057023 - Regulation of gene expression during M-G1-phase in fission yeast through Plo1p and forkhead transcription factors.

Papadopoulou K et al. J Cell Sci 2008 Jan 01;121(Pt 1):38-47

PMID:21422229 - Assembly and architecture of precursor nodes during fission yeast cytokinesis.

Laporte D et al. J Cell Biol 2011 Mar 21;192(6):1005-21

PMID:37531259 - Membrane binding of endocytic myosin-1s is inhibited by a class of ankyrin repeat proteins.

Willet AH et al. Mol Biol Cell 2023 Oct 01;34(11):br17

PMID:14602073 - Spatial and temporal pathway for assembly and constriction of the contractile ring in fission yeast cytokinesis.

Wu JQ et al. Dev Cell 2003 Nov;5(5):723-34

PMID:29975157 - Analysis of the contribution of phosphoinositides to medial septation in fission yeast highlights the importance of PI(4,5)P 2 for medial contractile ring anchoring.

Snider CE et al. Mol Biol Cell 2018 Sep 01;29(18):2148-2155

PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.

Strachan J et al. J Cell Sci 2023 Dec 01;136(23)

PMID:33823663 - A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans.

Halova L et al. Open Biol 2021 Apr;11(4):200405

PMID:15509866 - Fkh2p and Sep1p regulate mitotic gene transcription in fission yeast.

Buck V et al. J Cell Sci 2004 Nov 01;117(Pt 23):5623-32

PMID:16864655 - Assembly of the cytokinetic contractile ring from a broad band of nodes in fission yeast.

Wu JQ et al. J Cell Biol 2006 Jul 31;174(3):391-402

PMID:9649518 - A screen for genes involved in the anaphase proteolytic pathway identifies tsm1(+), a novel Schizosaccharomyces pombe gene important for microtubule integrity.

Grishchuk EL et al. Genetics 1998 Jul;149(3):1251-64

PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.

Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7

PMID:31822915 - Mkt1 is required for RNAi-mediated silencing and establishment of heterochromatin in fission yeast.

Taglini F et al. Nucleic Acids Res 2020 Feb 20;48(3):1239-1253

PMID:10924454 - A new genetic method for isolating functionally interacting genes: high plo1(+)-dependent mutants and their suppressors define genes in mitotic and septation pathways in fission yeast.

Cullen CF et al. Genetics 2000 Aug;155(4):1521-34

PMID:16866873 - Actin-capping protein is involved in controlling organization of actin cytoskeleton together with ADF/cofilin, profilin and F-actin crosslinking proteins in fission yeast.

Nakano K et al. Genes Cells 2006 Aug;11(8):893-905

PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.

Skribbe M et al. Mol Cell 2025 Feb 19;

PMID:19547744 - Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Beltrao P et al. PLoS Biol 2009 Jun 16;7(6):e1000134

PMID:22681890 - Hierarchical modularity and the evolution of genetic interactomes across species.

Ryan CJ et al. Mol Cell 2012 Jun 08;46(5):691-704

PMID:32848252 - Closed mitosis requires local disassembly of the nuclear envelope.

Dey G et al. Nature 2020 Sep;585(7823):119-123

PMID:9786952 - imp2, a new component of the actin ring in the fission yeast Schizosaccharomyces pombe.

Demeter J et al. J Cell Biol 1998 Oct 19;143(2):415-27

PMID:33313903 - Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast.

Rubio A et al. Nucleic Acids Res 2021 Jan 11;49(1):383-399

PMID:28784611 - Phosphoinositide-mediated ring anchoring resists perpendicular forces to promote medial cytokinesis.

Snider CE et al. J Cell Biol 2017 Oct 02;216(10):3041-3050

PMID:22740629 - α-Actinin and fimbrin cooperate with myosin II to organize actomyosin bundles during contractile-ring assembly.

Laporte D et al. Mol Biol Cell 2012 Aug;23(16):3094-110

PMID:29249658 - Mechanisms Connecting the Conserved Protein Kinases Ssp1, Kin1, and Pom1 in Fission Yeast Cell Polarity and Division.

Lee ME et al. Curr Biol 2018 Jan 08;28(1):84-92.e4

PMID:22427686 - Characterization of Mid1 domains for targeting and scaffolding in fission yeast cytokinesis.

Lee IJ et al. J Cell Sci 2012 Jun 15;125(Pt 12):2973-85

PMID:23966468 - Cooperation between Rho-GEF Gef2 and its binding partner Nod1 in the regulation of fission yeast cytokinesis.

Zhu YH et al. Mol Biol Cell 2013 Oct;24(20):3187-204

PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.

Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:29996109 - Quantitative Phosphoproteomics Reveals the Signaling Dynamics of Cell-Cycle Kinases in the Fission Yeast Schizosaccharomyces pombe.

Swaffer MP et al. Cell Rep 2018 Jul 10;24(2):503-514

PMID:9649519 - Isolation and characterization of new fission yeast cytokinesis mutants.

Balasubramanian MK et al. Genetics 1998 Jul;149(3):1265-75

PMID:15517003 - Organization of a sterol-rich membrane domain by cdc15p during cytokinesis in fission yeast.

Takeda T et al. Nat Cell Biol 2004 Nov;6(11):1142-4

PMID:22573890 - Fission yeast Cyk3p is a transglutaminase-like protein that participates in cytokinesis and cell morphogenesis.

Pollard LW et al. Mol Biol Cell 2012 Jul;23(13):2433-44

PMID:26702831 - Oligomerization but Not Membrane Bending Underlies the Function of Certain F-BAR Proteins in Cell Motility and Cytokinesis.

McDonald NA et al. Dev Cell 2015 Dec 21;35(6):725-36

PMID:28914606 - Nanoscale architecture of the Schizosaccharomyces pombe contractile ring.

McDonald NA et al. Elife 2017 Sep 15;6

PMID:36749320 - Multiple polarity kinases inhibit phase separation of F-BAR protein Cdc15 and antagonize cytokinetic ring assembly in fission yeast.

Bhattacharjee R et al. Elife 2023 Feb 07;12

PMID:37158439 - The fission yeast cytokinetic ring component Fic1 promotes septum formation.

Rossi AM et al. Biol Open 2023 May 15;12(5)

PMID:12939254 - The PCH family protein, Cdc15p, recruits two F-actin nucleation pathways to coordinate cytokinetic actin ring formation in Schizosaccharomyces pombe.

Carnahan RH et al. J Cell Biol 2003 Sep 01;162(5):851-62

PMID:35108037 - Fission yeast paxillin contains two Cdc15 binding motifs for robust recruitment to the cytokinetic ring.

Snider CE et al. Mol Biol Cell 2022 Apr 01;33(4):br4

PMID:24115772 - SIN-dependent phosphoinhibition of formin multimerization controls fission yeast cytokinesis.

Bohnert KA et al. Genes Dev 2013 Oct 01;27(19):2164-77

PMID:10459013 - Sid2p, a spindle pole body kinase that regulates the onset of cytokinesis.

Sparks CA et al. J Cell Biol 1999 Aug 23;146(4):777-90

PMID:32062975 - Phosphoproteomics Reveals Novel Targets and Phosphoprotein Networks in Cell Cycle Mediated by Dsk1 Kinase.

Wu M et al. J Proteome Res 2020 Apr 03;19(4):1776-1787

PMID:33357436 - Opposite Surfaces of the Cdc15 F-BAR Domain Create a Membrane Platform That Coordinates Cytoskeletal and Signaling Components for Cytokinesis.

Snider CE et al. Cell Rep 2020 Dec 22;33(12):108526

PMID:40114852 - Characterization and comparison of Schizosaccharomyces pombe cdc15 temperature-sensitive mutants.

Turner LA et al. MicroPubl Biol 2025;2025

PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs

PMID:10769201 - The S. pombe orthologue of the S. cerevisiae mob1 gene is essential and functions in signalling the onset of septum formation.

Salimova E et al. J Cell Sci 2000 May;113 ( Pt 10):1695-704

PMID:21376595 - IQGAP-related Rng2p organizes cortical nodes and ensures position of cell division in fission yeast.

Padmanabhan A et al. Curr Biol 2011 Mar 22;21(6):467-72

PMID:24127216 - The formins Cdc12 and For3 cooperate during contractile ring assembly in cytokinesis.

Coffman VC et al. J Cell Biol 2013 Oct 14;203(1):101-14

PMID:26167880 - SR protein kinases promote splicing of nonconsensus introns.

Lipp JJ et al. Nat Struct Mol Biol 2015 Aug;22(8):611-7

PMID:15933715 - Etd1p is a novel protein that links the SIN cascade with cytokinesis.

Daga RR et al. EMBO J 2005 Jul 06;24(13):2436-46

PMID:23297348 - Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase.

Chen JS et al. Mol Cell Proteomics 2013 May;12(5):1074-86

PMID:31276301 - A unique kinesin-like protein, Klp8, is involved in mitosis and cell morphology through microtubule stabilization.

Kashiwazaki J et al. Cytoskeleton (Hoboken) 2019 May;76(5):355-367

PMID:30332655 - Paxillin-Mediated Recruitment of Calcineurin to the Contractile Ring Is Required for the Correct Progression of Cytokinesis in Fission Yeast.

Martín-García R et al. Cell Rep 2018 Oct 16;25(3):772-783.e4

PMID:34402513 - Phosphorylation in the intrinsically disordered region of F-BAR protein Imp2 regulates its contractile ring recruitment.

Willet AH et al. J Cell Sci 2021 Aug 15;134(16)

PMID:31509478 - The intrinsically disordered region of the cytokinetic F-BAR protein Cdc15 performs a unique essential function in maintenance of cytokinetic ring integrity.

Mangione MC et al. Mol Biol Cell 2019 Oct 15;30(22):2790-2801

PMID:34296454 - The TOR-dependent phosphoproteome and regulation of cellular protein synthesis.

Mak T et al. EMBO J 2021 Aug 16;40(16):e107911

PMID:20876564 - Antagonistic roles of PP2A-Pab1 and Etd1 in the control of cytokinesis in fission yeast.

Lahoz A et al. Genetics 2010 Dec;186(4):1261-70

PMID:23615450 - Separate roles of IQGAP Rng2p in forming and constricting the Schizosaccharomyces pombe cytokinetic contractile ring.

Tebbs IR et al. Mol Biol Cell 2013 Jun;24(12):1904-17

PMID:10805785 - Sid4p is required to localize components of the septation initiation pathway to the spindle pole body in fission yeast.

Chang L et al. Proc Natl Acad Sci U S A 2000 May 09;97(10):5249-54

PMID:10545452 - Drc1p/Cps1p, a 1,3-beta-glucan synthase subunit, is essential for division septum assembly in Schizosaccharomyces pombe.

Liu J et al. Genetics 1999 Nov;153(3):1193-203

PMID:8039497 - The cdc7 protein kinase is a dosage dependent regulator of septum formation in fission yeast.

Fankhauser C et al. EMBO J 1994 Jul 01;13(13):3011-9

PMID:27898700 - Sbg1 Is a Novel Regulator for the Localization of the β-Glucan Synthase Bgs1 in Fission Yeast.

Davidson R et al. PLoS One 2016;11(11):e0167043

PMID:29343550 - Cdk1-dependent phosphoinhibition of a formin-F-BAR interaction opposes cytokinetic contractile ring formation.

Willet AH et al. Mol Biol Cell 2018 Mar 15;29(6):713-721

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:22918943 - Anillin-related protein Mid1p coordinates the assembly of the cytokinetic contractile ring in fission yeast.

Saha S et al. Mol Biol Cell 2012 Oct;23(20):3982-92

PMID:24790095 - Characterization of the roles of Blt1p in fission yeast cytokinesis.

Goss JW et al. Mol Biol Cell 2014 Jul 01;25(13):1946-57

PMID:26132084 - Cooperation between Paxillin-like Protein Pxl1 and Glucan Synthase Bgs1 Is Essential for Actomyosin Ring Stability and Septum Formation in Fission Yeast.

Cortés JC et al. PLoS Genet 2015 Jul;11(7):e1005358

PMID:8834798 - Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring.

Chang F et al. J Cell Sci 1996 Jan;109 ( Pt 1):131-42

PMID:15743909 - Profilin-mediated competition between capping protein and formin Cdc12p during cytokinesis in fission yeast.

Kovar DR et al. Mol Biol Cell 2005 May;16(5):2313-24

PMID:22347452 - The SET domain protein, Set3p, promotes the reliable execution of cytokinesis in Schizosaccharomyces pombe.

Rentas S et al. PLoS One 2012;7(2):e31224

PMID:25159149 - Contractile ring stability in S. pombe depends on F-BAR protein Cdc15p and Bgs1p transport from the Golgi complex.

Arasada R et al. Cell Rep 2014 Sep 11;8(5):1533-44

PMID:12411492 - Plo1(+) regulates gene transcription at the M-G(1) interval during the fission yeast mitotic cell cycle.

Anderson M et al. EMBO J 2002 Nov 01;21(21):5745-55

PMID:28218250 - Chromatin remodeller Fun30 Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Lee J et al. Nat Commun 2017 Feb 20;8:14527

PMID:11870208 - F-actin ring formation and the role of F-actin cables in the fission yeast Schizosaccharomyces pombe.

Arai R et al. J Cell Sci 2002 Mar 01;115(Pt 5):887-98

PMID:25688133 - The F-BAR Cdc15 promotes contractile ring formation through the direct recruitment of the formin Cdc12.

Willet AH et al. J Cell Biol 2015 Feb 16;208(4):391-9

PMID:36287824 - Imp2p forms actin-dependent clusters and imparts stiffness to the contractile ring.

Bellingham-Johnstun K et al. Mol Biol Cell 2022 Dec 01;33(14):ar145

PMID:10503548 - Analysis of the cps1 gene provides evidence for a septation checkpoint in Schizosaccharomyces pombe.

Le Goff X et al. Mol Gen Genet 1999 Aug;262(1):163-72

PMID:26776521 - The Tubulation Activity of a Fission Yeast F-BAR Protein Is Dispensable for Its Function in Cytokinesis.

McDonald NA et al. Cell Rep 2016 Jan 26;14(3):534-546

PMID:29813053 - Specific detection of fission yeast primary septum reveals septum and cleavage furrow ingression during early anaphase independent of mitosis completion.

G Cortés JC et al. PLoS Genet 2018 May;14(5):e1007388

PMID:32878942 - Phosphoregulation of the cytokinetic protein Fic1 contributes to fission yeast growth polarity establishment.

Bohnert KA et al. J Cell Sci 2020 Sep 17;133(18)

PMID:18272786 - Pxl1p, a paxillin-related protein, stabilizes the actomyosin ring during cytokinesis in fission yeast.

Ge W et al. Mol Biol Cell 2008 Apr;19(4):1680-92

PMID:15302827 - The forkhead transcription factor Fkh2 regulates the cell division cycle of Schizosaccharomyces pombe.

Bulmer R et al. Eukaryot Cell 2004 Aug;3(4):944-54

PMID:11854409 - The multiprotein exocyst complex is essential for cell separation in Schizosaccharomyces pombe.

Wang H et al. Mol Biol Cell 2002 Feb;13(2):515-29

PMID:21712547 - Mitotic substrates of the kinase aurora with roles in chromatin regulation identified through quantitative phosphoproteomics of fission yeast.

Koch A et al. Sci Signal 2011 Jun 28;4(179):rs6

PMID:10759889 - Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Ding DQ et al. Genes Cells 2000 Mar;5(3):169-90

PMID:21885283 - Distinct roles for F-BAR proteins Cdc15p and Bzz1p in actin polymerization at sites of endocytosis in fission yeast.

Arasada R et al. Curr Biol 2011 Sep 13;21(17):1450-9

PMID:20603077 - Dephosphorylation of F-BAR protein Cdc15 modulates its conformation and stimulates its scaffolding activity at the cell division site.

Roberts-Galbraith RH et al. Mol Cell 2010 Jul 09;39(1):86-99

PMID:30853434 - NDR Kinase Sid2 Drives Anillin-like Mid1 from the Membrane to Promote Cytokinesis and Medial Division Site Placement.

Willet AH et al. Curr Biol 2019 Mar 18;29(6):1055-1063.e2

PMID:25825517 - A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast.

Dudin O et al. J Cell Biol 2015 Mar 30;208(7):897-911

PMID:32101481 - DYRK kinase Pom1 drives F-BAR protein Cdc15 from the membrane to promote medial division.

Bhattacharjee R et al. Mol Biol Cell 2020 Apr 15;31(9):917-929

PMID:37746062 - Polarity kinases that phosphorylate F-BAR protein Cdc15 have unique localization patterns during cytokinesis and contributions to preventing tip septation in Schizosaccharomyces pombe .

Igarashi MG et al. MicroPubl Biol 2023;2023

PMID:39476757 - Characterization of Ksg1 protein kinase-dependent phosphoproteome in the fission yeast S. pombe.

Cipak L et al. Biochem Biophys Res Commun 2024 Oct 25;736:150895

PMID:39705284 - Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast.

Bérard M et al. PLoS Biol 2024 Dec 20;22(12):e3002963

PMID:958201 - Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe.

Nurse P et al. Mol Gen Genet 1976 Jul 23;146(2):167-78

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36

PMID:762020 - Uncontrolled septation in a cell division cycle mutant of the fission yeast Schizosaccharomyces pombe.

Minet M et al. J Bacteriol 1979 Jan;137(1):440-6

PMID:20118936 - Schizosaccharomyces pombe genome-wide nucleosome mapping reveals positioning mechanisms distinct from those of Saccharomyces cerevisiae.

Lantermann AB et al. Nat Struct Mol Biol 2010 Feb;17(2):251-7

PMID:22119525 - SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast.

Singh NS et al. Curr Biol 2011 Dec 06;21(23):1968-78

PMID:19075108 - Assembly of normal actomyosin rings in the absence of Mid1p and cortical nodes in fission yeast.

Huang Y et al. J Cell Biol 2008 Dec 15;183(6):979-88

PMID:31591131 - F-BAR Cdc15 Promotes Cdc42 Activation During Cytokinesis and Cell Polarization in Schizosaccharomyces pombe .

Hercyk BS et al. Genetics 2019 Dec;213(4):1341-1356

PMID:26941334 - Unique spatiotemporal activation pattern of Cdc42 by Gef1 and Scd1 promotes different events during cytokinesis.

Wei B et al. Mol Biol Cell 2016 Apr 15;27(8):1235-45

PMID:7634333 - The S. pombe cdc15 gene is a key element in the reorganization of F-actin at mitosis.

Fankhauser C et al. Cell 1995 Aug 11;82(3):435-44

PMID:18256290 - Schizosaccharomyces pombe Pxl1 is a paxillin homologue that modulates Rho1 activity and participates in cytokinesis.

Pinar M et al. Mol Biol Cell 2008 Apr;19(4):1727-38

PMID:19139265 - The SH3 domains of two PCH family members cooperate in assembly of the Schizosaccharomyces pombe contractile ring.

Roberts-Galbraith RH et al. J Cell Biol 2009 Jan 12;184(1):113-27

PMID:20826805 - Fission yeast germinal center (GC) kinase Ppk11 interacts with Pmo25 and plays an auxiliary role in concert with the morphogenesis Orb6 network (MOR) in cell morphogenesis.

Goshima T et al. J Biol Chem 2010 Nov 05;285(45):35196-205

PMID:18257517 - Phosphoproteome analysis of fission yeast.

Wilson-Grady JT et al. J Proteome Res 2008 Mar;7(3):1088-97

PMID:23093943 - Cytokinesis-based constraints on polarized cell growth in fission yeast.

Bohnert KA et al. PLoS Genet 2012;8(10):e1003004

PMID:27984725 - CDK Substrate Phosphorylation and Ordering the Cell Cycle.

Swaffer MP et al. Cell 2016 Dec 15;167(7):1750-1761.e16

PMID:18951025 - The SIN kinase Sid2 regulates cytoplasmic retention of the S. pombe Cdc14-like phosphatase Clp1.

Chen CT et al. Curr Biol 2008 Oct 28;18(20):1594-9

PMID:20805322 - The mitosis-to-interphase transition is coordinated by cross talk between the SIN and MOR pathways in Schizosaccharomyces pombe.

Ray S et al. J Cell Biol 2010 Sep 06;190(5):793-805

PMID:24713849 - Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex.

Egan ED et al. RNA 2014 Jun;20(6):867-81

PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.

Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87

PMID:25428987 - The Cdc15 and Imp2 SH3 domains cooperatively scaffold a network of proteins that redundantly ensure efficient cell division in fission yeast.

Ren L et al. Mol Biol Cell 2015 Jan 15;26(2):256-69

PMID:25977474 - A role for F-BAR protein Rga7p during cytokinesis in S. pombe.

Arasada R et al. J Cell Sci 2015 Jul 01;128(13):2259-68

PMID:16687577 - Cell cycle-dependent roles for the FCH-domain protein Cdc15p in formation of the actomyosin ring in Schizosaccharomyces pombe.

Wachtler V et al. Mol Biol Cell 2006 Jul;17(7):3254-66

PMID:22559741 - A conserved histone deacetylase with a role in the regulation of cytokinesis in Schizosaccharomyces pombe.

Grewal C et al. Cell Div 2012 May 04;7(1):13

PMID:25908789 - A new transcription factor for mitosis: in Schizosaccharomyces pombe, the RFX transcription factor Sak1 works with forkhead factors to regulate mitotic expression.

Garg A et al. Nucleic Acids Res 2015 Aug 18;43(14):6874-88