protein coding gene - SPAC212.12 - S. pombe specific GPI anchored protein family 1
Gene summary
Systematic ID
SPAC212.12
Product
S. pombe specific GPI anchored protein family 1
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
SPNG7
UniProt ID
C6Y4B5
Characterisation status
Schizosaccharomyces pombe specific protein, uncharacterized
Feature type
mRNA gene
Genomic location
chromosome I: 15855..16226 forward strand
Annotation
GO cellular component
GO:0009897
-
external side of plasma membrane
References:
GO_REF:0000051
Modification
MOD:00818
-
glycosylphosphatidylinositolated residue
References:
PB_REF:0000007
PMID:36408920
Protein sequence feature
SO:0000418
-
signal_peptide
References:
PMID:36408920
SO:0001812
-
transmembrane_helix
References:
PMID:11152613
Quantitative gene expression
PBO:0011963
-
RNA level
References:
PMID:23101633
Taxonomic conservation
PBO:0016878
-
Schizosaccharomyces pombe specific
Warnings
PBO:0000070
-
gene structure updated
References:
PMID:21511999
Protein features
ID
Name
InterPro name
DB name
Transmembrane alpha helix
DeepTMHMM
References / Literature
PB_REF:0000007
-
Prediction of GPI-anchored proteins with pointer neural networks
PMID:40063661
-
Fission yeast Caprin protein is required for efficient heterochromatin establishment.
Zhang H et al. PLoS Genet 2025 Mar 10;21(3):e1011620
PMID:18488015
-
Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution.
Wilhelm BT et al. Nature 2008 Jun 26;453(7199):1239-43
PMID:23101633
-
Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:11152613
-
Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes.
Krogh A et al. J Mol Biol 2001 Jan 19;305(3):567-80
PMID:33109728
-
High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library.
Varberg JM et al. G3 (Bethesda) 2020 Dec 03;10(12):4649-4663
PMID:36408920
-
UniProt: the Universal Protein Knowledgebase in 2023.
UniProt Consortium Nucleic Acids Res 2023 Jan 06;51(D1):D523-D531
PMID:32499408
-
The molecular chaperone Hsp90 regulates heterochromatin assembly through stabilizing multiple complexes in fission yeast.
Sun L et al. J Cell Sci 2020 Jul 07;133(13)
GO_REF:0000051
-
S. pombe keyword mapping
PMID:21511999
-
Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:40015273
-
A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.
Skribbe M et al. Mol Cell 2025 Feb 19;