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protein coding gene - SPAC222.17 - conserved fungal protein, probable TBC1 domain (GAP)

Gene summary

Systematic ID
SPAC222.17
Product
conserved fungal protein, probable TBC1 domain (GAP)
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
SPNG161, SPNCRNA.162
UniProt ID
C6Y4B9
Characterisation status
conserved unknown
Feature type
mRNA gene
Genomic location
chromosome I: 967583..968254 reverse strand

Annotation

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002924 - decreased cell population growth on maltose carbon source

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Genotypes:

FYPO:0005261 - increased cell population growth on galactose carbon source

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Genotypes:

FYPO:0009094 - increased cell population growth on lysine and proline nitrogen source

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Genotypes:

FYPO:0000764 - resistance to cycloheximide

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FYPO:0002693 - resistance to diamide

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Genotypes:

FYPO:0009038 - resistance to egtazic acid

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FYPO:0009035 - resistance to formamide

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FYPO:0009083 - resistance to lithium chloride and methyl methanesulfonate

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FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

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FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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FYPO:0000830 - resistance to vanadate

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FYPO:0009069 - sensitive to ciclopirox olamine

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FYPO:0000842 - sensitive to ethanol during vegetative growth

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FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

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Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011063 - conserved in fungi only

PBO:0000055 - no apparent S. cerevisiae ortholog

PBO:0006222 - predominantly single copy (one to one)

Warnings

PBO:0000082 - new gene

References:

PBO:0000406 - previously annotated as ncRNA

Orthologs

References / Literature

PMID:23163955 - Analysis of stress-induced duplex destabilization (SIDD) properties of replication origins, genes and intergenes in the fission yeast, Schizosaccharomyces pombe.
Yadav MP et al. BMC Res Notes 2012 Nov 19;5:643
PMID:18488015 - Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution.
Wilhelm BT et al. Nature 2008 Jun 26;453(7199):1239-43
PMID:26896847 - Ensembl comparative genomics resources.
Herrero J et al. Database (Oxford) 2016;2016
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12