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protein coding gene - rrn10 (SPAC22E12.08) - RNA polymerase I upstream activation factor complex subunit Rrn10

Gene summary

Standard name
rrn10
Systematic ID
SPAC22E12.08
Product
RNA polymerase I upstream activation factor complex subunit Rrn10
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
Q10360
ORFeome ID
02/02B04
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome I: 5033437..5034586 forward strand

Annotation

GO biological process

GO:0006361 - transcription initiation at RNA polymerase I promoter

References:

GO cellular component

GO:0005829 - cytosol

References:

GO:0005634 - nucleus

References:

GO:0000500 - RNA polymerase I upstream activating factor complex

References:

GO molecular function

GO:0005515 - protein binding

References:

GO:0001181 - RNA polymerase I general transcription initiation factor activity

References:

Quantitative gene expression

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0000059 - abnormal mitotic cell cycle

References:

Genotypes:

FYPO:0003529 - inviable after spore germination, multiple cell divisions, cell cycle arrest in mitotic interphase, elongated cells

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

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Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011063 - conserved in fungi only

PBO:0006222 - predominantly single copy (one to one)

Protein features

IDNameInterPro nameDB name
PF05234UAF_Rrn10Rrn10PFAM

Orthologs

References / Literature

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:26771498 - A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.
Vo TV et al. Cell 2016 Jan 14;164(1-2):310-323
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:12490702 - Characterization of the fission yeast ribosomal DNA binding factor: components share homology with Upstream Activating Factor and with SWI/SNF subunits.
Liu M et al. Nucleic Acids Res 2002 Dec 15;30(24):5347-59