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protein coding gene - aim41 (SPAC22F3.15) - mitochondrial protien, implicated in tRNA metabolism Aim41

Gene summary

Standard name
aim41
Systematic ID
SPAC22F3.15
Product
mitochondrial protien, implicated in tRNA metabolism Aim41
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
C6Y4B8
Characterisation status
conserved unknown
Feature type
mRNA gene
Genomic location
chromosome I: 692567..693061 forward strand

Annotation

GO cellular component

GO:0005759 - mitochondrial matrix

References:

GO molecular function

GO:0016884 - carbon-nitrogen ligase activity, with glutamine as amido-N-donor

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Qualitative gene expression

PomGeneEx:0000019 - protein level decreased

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Quantitative gene expression

PBO:0006310 - protein level

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PBO:0011963 - RNA level

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Single locus phenotype

FYPO:0009038 - resistance to egtazic acid

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Genotypes:

FYPO:0009035 - resistance to formamide

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Genotypes:

FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

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Genotypes:

FYPO:0001034 - resistance to tunicamycin

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Genotypes:

FYPO:0000830 - resistance to vanadate

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Genotypes:

FYPO:0000104 - sensitive to cycloheximide

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Genotypes:

FYPO:0000799 - sensitive to diamide

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Genotypes:

FYPO:0009071 - sensitive to itraconazole

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Genotypes:

FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

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Genotypes:

FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

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Genotypes:

FYPO:0002328 - sensitive to terbinafine

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Genotypes:

Taxonomic conservation

PBO:0011067 - conserved in bacteria

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

Warnings

PBO:0000082 - new gene

References:

Protein features

IDNameInterPro nameDB name
PF09424YqeYYqeY/Aim41Pfam
G3DSA:1.10.1510.10YqeY/Aim41_NCATH-Gene3D
SSF89095Asn/Gln_tRNA_amidoTrase-B-likeSUPERFAMILY
PTHR28055YqeY/Aim41PANTHER
CoilCOILS

Orthologs

References / Literature

GO_REF:0000051 - S. pombe keyword mapping
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:18488015 - Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution.
Wilhelm BT et al. Nature 2008 Jun 26;453(7199):1239-43
PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.
Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105
PMID:41974504 - Nuclear basket subunits Nup211 and Rsm1 influence RNA 3'-processing and transcription termination in fission yeast.
Bednor L et al. RNA 2026 Apr 13;
GO_REF:0000002 - Comments