protein coding gene - rtf1 (SPAC22F8.07c) - RNA polymerase I termination factor Rtf1

Gene summary

Standard name

rtf1

Systematic ID

SPAC22F8.07c

Product

RNA polymerase I termination factor Rtf1

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

Q9UUI6

ORFeome ID

45/45E04

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome I: 4797195..4799127 reverse strand

Annotation

Protein features

Orthologs

• TTF1 (HGNC:12397) Homo sapiens
• rtf1 (SJAG_00073) Schizosaccharomyces japonicus
• REB1 (YBR049C) Saccharomyces cerevisiae
• NSI1 (YDR026C) Saccharomyces cerevisiae

References / Literature

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.

Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:37615341 - Schizosaccharomyces pombe Rtf2 is important for replication fork barrier activity of RTS1 via splicing of Rtf1 .

Budden AM et al. Elife 2023 Aug 24;12

PMID:21504829 - Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Stewart EV et al. Mol Cell 2011 Apr 22;42(2):160-71

PMID:24957674 - Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.

Anver S et al. EMBO Rep 2014 Aug;15(8):894-902

PMID:12161753 - The transcriptional program of meiosis and sporulation in fission yeast.

Mata J et al. Nat Genet 2002 Sep;32(1):143-7

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:25776556 - The Human RNA Polymerase I Transcription Terminator Complex Acts as a Replication Fork Barrier That Coordinates the Progress of Replication with rRNA Transcription Activity.

Akamatsu Y et al. Mol Cell Biol 2015 May;35(10):1871-81

PMID:28974540 - The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components.

Salas-Pino S et al. J Cell Biol 2017 Nov 06;216(11):3591-3608

PMID:32366382 - Spt5 Phosphorylation and the Rtf1 Plus3 Domain Promote Rtf1 Function through Distinct Mechanisms.

Chen JJ et al. Mol Cell Biol 2020 Jul 14;40(15)

PMID:33568651 - Replication dynamics of recombination-dependent replication forks.

Naiman K et al. Nat Commun 2021 Feb 10;12(1):923

PMID:16537923 - Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast.

Todd BL et al. Mol Cell Biol 2006 Apr;26(7):2817-31

PMID:22681890 - Hierarchical modularity and the evolution of genetic interactomes across species.

Ryan CJ et al. Mol Cell 2012 Jun 08;46(5):691-704

PMID:18723894 - Rtf1-mediated eukaryotic site-specific replication termination.

Eydmann T et al. Genetics 2008 Sep;180(1):27-39

PMID:12840005 - Complex mechanism of site-specific DNA replication termination in fission yeast.

Codlin S et al. EMBO J 2003 Jul 01;22(13):3431-40

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

EMBL:AJ627891 - Unknown title

PMID:28218250 - Chromatin remodeller Fun30 Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Lee J et al. Nat Commun 2017 Feb 20;8:14527

PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.

Rodríguez-López M et al. Elife 2023 Oct 03;12