protein coding gene - eng2 (SPAC23D3.10c) - cell wall and ascospore endo-1,3-beta-glucanase Eng2

Gene summary

Standard name

eng2

Systematic ID

SPAC23D3.10c

Product

cell wall and ascospore endo-1,3-beta-glucanase Eng2

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

Q09850

ORFeome ID

46/46E09

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome I: 4355410..4358192 reverse strand

Annotation

Protein features

Orthologs

• eng2 (SJAG_01017) Schizosaccharomyces japonicus
• ACF2 (YLR144C) Saccharomyces cerevisiae
• DSE4 (YNR067C) Saccharomyces cerevisiae

References / Literature

GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference

PMID:25825517 - A formin-nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast.

Dudin O et al. J Cell Biol 2015 Mar 30;208(7):897-911

PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.

Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105

PMID:12161753 - The transcriptional program of meiosis and sporulation in fission yeast.

Mata J et al. Nat Genet 2002 Sep;32(1):143-7

PMID:20531409 - Global coordination of transcriptional control and mRNA decay during cellular differentiation.

Amorim MJ et al. Mol Syst Biol 2010 Jun 08;6:380

PMID:15194814 - Role of the alpha-glucanase Agn1p in fission-yeast cell separation.

Dekker N et al. Mol Biol Cell 2004 Aug;15(8):3903-14

PMID:25040903 - Eng2 is a component of a dynamic protein complex required for endocytic uptake in fission yeast.

Encinar del Dedo J et al. Traffic 2014 Oct;15(10):1122-42

PMID:7275933 - Isolation, properties, function, and regulation of endo-(1 leads to 3)-beta-glucanases in Schizosaccharomyces pombe.

Reichelt BY et al. J Bacteriol 1981 Sep;147(3):1085-94

PMID:26771498 - A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.

Vo TV et al. Cell 2016 Jan 14;164(1-2):310-323

PMID:21504829 - Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Stewart EV et al. Mol Cell 2011 Apr 22;42(2):160-71

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36

GO_REF:0000108 - Automatic assignment of GO terms using logical inference, based on on inter-ontology links.

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:36478272 - Translation-complex profiling of fission yeast cells reveals dynamic rearrangements of scanning ribosomal subunits upon nutritional stress.

Duncan CDS et al. Nucleic Acids Res 2022 Dec 09;50(22):13011-13025

PMID:31495586 - Capping Protein Insulates Arp2/3-Assembled Actin Patches from Formins.

Billault-Chaumartin I et al. Curr Biol 2019 Oct 07;29(19):3165-3176.e6

GO_REF:0000033 - Annotation inferences using phylogenetic trees

GO_REF:0000036 - Manual annotations that require more than one source of functional data to support the assignment of the associated GO term

PMID:19542306 - {beta}-glucanase Eng2 is required for ascus wall endolysis after sporulation in the fission yeast Schizosaccharomyces pombe.

Encinar del Dedo J et al. Eukaryot Cell 2009 Aug;8(8):1278-86

PMID:34504165 - Eng2, a new player involved in feedback loop regulation of Cdc42 activity in fission yeast.

García P et al. Sci Rep 2021 Sep 09;11(1):17872

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.

Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7

PMID:31626996 - Multiplexed proteome profiling of carbon source perturbations in two yeast species with SL-SP3-TMT.

Paulo JA et al. J Proteomics 2020 Jan 06;210:103531

PMID:33313903 - Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast.

Rubio A et al. Nucleic Acids Res 2021 Jan 11;49(1):383-399

PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.

Rodríguez-López M et al. Elife 2023 Oct 03;12

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:25452419 - Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Sideri T et al. G3 (Bethesda) 2014 Dec 01;5(1):145-55

PMID:22681890 - Hierarchical modularity and the evolution of genetic interactomes across species.

Ryan CJ et al. Mol Cell 2012 Jun 08;46(5):691-704

PMID:26345368 - A new phosphate-starvation response in fission yeast requires the endocytic function of myosin I.

Petrini E et al. J Cell Sci 2015 Oct 15;128(20):3707-13

PMID:30647105 - Comparative Genomic Screen in Two Yeasts Reveals Conserved Pathways in the Response Network to Phenol Stress.

Alhoch B et al. G3 (Bethesda) 2019 Mar 07;9(3):639-650

PMID:17933563 - Characterization of the endo-beta-1,3-glucanase activity of S. cerevisiae Eng2 and other members of the GH81 family.

Martín-Cuadrado AB et al. Fungal Genet Biol 2008 Apr;45(4):542-53