protein coding gene - cdc25 (SPAC24H6.05) - protein tyrosine phosphatase (M phase inducer) Cdc25

Gene summary

Standard name

cdc25

Systematic ID

SPAC24H6.05

Product

protein tyrosine phosphatase (M phase inducer) Cdc25

Organism

Schizosaccharomyces pombe (fission yeast)

Synonyms

sal2

UniProt ID

P06652

ORFeome ID

40/40F12

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome I: 479228..482373 reverse strand

Annotation

Protein features

Orthologs

• CDC25A (HGNC:1725) Homo sapiens
• CDC25B (HGNC:1726) Homo sapiens
• CDC25C (HGNC:1727) Homo sapiens
• cdc25 (SJAG_04332) Schizosaccharomyces japonicus
• MIH1 (YMR036C) Saccharomyces cerevisiae

References / Literature

PMID:9490640 - A NIMA homologue promotes chromatin condensation in fission yeast.

Krien MJ et al. J Cell Sci 1998 Apr;111 ( Pt 7):967-76

PMID:21779494 - Ras signaling in yeast.

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PMID:27736299 - A genome-wide screen to identify genes controlling the rate of entry into mitosis in fission yeast.

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PMID:9013342 - The size control of fission yeast revisited.

Sveiczer A et al. J Cell Sci 1996 Dec;109 ( Pt 12):2947-57

PMID:9383050 - Mutational analysis of Cdc19p, a Schizosaccharomyces pombe MCM protein.

Forsburg SL et al. Genetics 1997 Nov;147(3):1025-41

PMID:33313903 - Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast.

Rubio A et al. Nucleic Acids Res 2021 Jan 11;49(1):383-399

PMID:26990381 - Lipid Droplets Form from Distinct Regions of the Cell in the Fission Yeast Schizosaccharomyces pombe.

Meyers A et al. Traffic 2016 Jun;17(6):657-69

PMID:7808417 - A Drosophila gene encoding a DEAD box RNA helicase can suppress loss of wee1/mik1 function in Schizosaccharomyces pombe.

Warbrick E et al. Mol Gen Genet 1994 Dec 01;245(5):654-7

PMID:24713849 - Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex.

Egan ED et al. RNA 2014 Jun;20(6):867-81

PMID:1703321 - Complementation of the mitotic activator, p80cdc25, by a human protein-tyrosine phosphatase.

Gould KL et al. Science 1990 Dec 14;250(4987):1573-6

PMID:29065217 - The fission yeast MAPK Spc1 senses perturbations in Cdc25 and Wee1 activities and targets Rad24 to restore this balance.

Paul M et al. Yeast 2018 Mar;35(3):261-271

PMID:7961734 - Low molecular weight protein-tyrosine phosphatases are highly conserved between fission yeast and man.

Mondesert O et al. J Biol Chem 1994 Nov 11;269(45):27996-9

PMID:18077559 - Biphasic incorporation of centromeric histone CENP-A in fission yeast.

Takayama Y et al. Mol Biol Cell 2008 Feb;19(2):682-90

PMID:9135149 - Nif1, a novel mitotic inhibitor in Schizosaccharomyces pombe.

Wu L et al. EMBO J 1997 Mar 17;16(6):1342-50

PMID:2534559 - Fission yeast cyclin: subcellular localisation and cell cycle regulation.

Alfa CE et al. J Cell Sci Suppl 1989;12:9-19

PMID:16453724 - Isolation and characterization of Schizosaccharomyces pombe cutmutants that block nuclear division but not cytokinesis.

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PMID:29249658 - Mechanisms Connecting the Conserved Protein Kinases Ssp1, Kin1, and Pom1 in Fission Yeast Cell Polarity and Division.

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PMID:19547744 - Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

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PMID:26918805 - Consequences of abnormal CDK activity in S phase.

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PMID:10940030 - Spy1, a histidine-containing phosphotransfer signaling protein, regulates the fission yeast cell cycle through the Mcs4 response regulator.

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PMID:11085271 - spo12 is a multicopy suppressor of mcs3 that is periodically expressed in fission yeast mitosis.

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PMID:11238887 - Roles of the mitotic inhibitors Wee1 and Mik1 in the G(2) DNA damage and replication checkpoints.

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PMID:8860233 - Forces acting on the fission yeast anaphase spindle.

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PMID:18235227 - Fission yeast TOR complex 2 activates the AGC-family Gad8 kinase essential for stress resistance and cell cycle control.

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PMID:2320127 - Regulation of mitosis by cyclic accumulation of p80cdc25 mitotic inducer in fission yeast.

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PMID:17998401 - Nuclear size control in fission yeast.

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PMID:1819509 - stf1: a new suppressor of the mitotic control gene, cdc25, in Schizosaccharomyces pombe.

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PMID:26412298 - A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Beckley JR et al. Mol Cell Proteomics 2015 Dec;14(12):3132-41

PMID:3796591 - Site-specific mutagenesis of cdc2+, a cell cycle control gene of the fission yeast Schizosaccharomyces pombe.

Booher R et al. Mol Cell Biol 1986 Oct;6(10):3523-30

PMID:2178610 - Fission yeast cdc25 is a cell-cycle regulated protein.

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PMID:15911625 - Functional homology among human and fission yeast Cdc14 phosphatases.

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PMID:1448087 - The fission yeast genes pyp1+ and pyp2+ encode protein tyrosine phosphatases that negatively regulate mitosis.

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PMID:22682874 - Sensor and effector kinases in DNA damage checkpoint regulate capacity for homologous recombination repair of fission yeast in G2 phase.

Yasuhira S et al. DNA Repair (Amst) 2012 Aug 01;11(8):666-75

PMID:8313892 - The Schizosaccharomyces pombe cdc5+ gene encodes an essential protein with homology to c-Myb.

Ohi R et al. EMBO J 1994 Jan 15;13(2):471-83

PMID:8467814 - Characterization of the fission yeast mcs2 cyclin and its associated protein kinase activity.

Molz L et al. EMBO J 1993 Apr;12(4):1723-32

PMID:8799851 - The kinetics of the B cyclin p56cdc13 and the phosphatase p80cdc25 during the cell cycle of the fission yeast Schizosaccharomyces pombe.

Creanor J et al. J Cell Sci 1996 Jun;109 ( Pt 6):1647-53

PMID:9182666 - Fission yeast dim1(+) encodes a functionally conserved polypeptide essential for mitosis.

Berry LD et al. J Cell Biol 1997 Jun 16;137(6):1337-54

PMID:22665807 - Multisite phosphoregulation of Cdc25 activity refines the mitotic entrance and exit switches.

Lu LX et al. Proc Natl Acad Sci U S A 2012 Jun 19;109(25):9899-904

PMID:31553675 - The phosphatase inhibitor Sds23 regulates cell division symmetry in fission yeast.

Schutt KL et al. Mol Biol Cell 2019 Nov 01;30(23):2880-2889

PMID:32878942 - Phosphoregulation of the cytokinetic protein Fic1 contributes to fission yeast growth polarity establishment.

Bohnert KA et al. J Cell Sci 2020 Sep 17;133(18)

PMID:22174761 - Roles of the DYRK kinase Pom2 in cytokinesis, mitochondrial morphology, and sporulation in fission yeast.

Wu P et al. PLoS One 2011;6(12):e28000

PMID:8187760 - Genetic analysis of cell morphogenesis in fission yeast--a role for casein kinase II in the establishment of polarized growth.

Snell V et al. EMBO J 1994 May 01;13(9):2066-74

PMID:12065422 - Schizosaccharomyces pombe NIMA-related kinase, Fin1, regulates spindle formation and an affinity of Polo for the SPB.

Grallert A et al. EMBO J 2002 Jun 17;21(12):3096-107

PMID:16096637 - Fission yeast MO25 protein is localized at SPB and septum and is essential for cell morphogenesis.

Kanai M et al. EMBO J 2005 Sep 07;24(17):3012-25

PMID:8455610 - Two fission yeast B-type cyclins, cig2 and Cdc13, have different functions in mitosis.

Bueno A et al. Mol Cell Biol 1993 Apr;13(4):2286-97

PMID:22182414 - Small heat-shock protein Hsp9 has dual functions in stress adaptation and stress-induced G2-M checkpoint regulation via Cdc25 inactivation in Schizosaccharomyces pombe.

Ahn J et al. Biochem Biophys Res Commun 2012 Jan 06;417(1):613-8

PMID:9843572 - The protein kinase Cdr2, related to Nim1/Cdr1 mitotic inducer, regulates the onset of mitosis in fission yeast.

Kanoh J et al. Mol Biol Cell 1998 Dec;9(12):3321-34

PMID:8413179 - Genetic analysis of human p34CDC2 function in fission yeast.

MacNeill SA et al. Mol Gen Genet 1993 Sep;240(3):315-22

PMID:12455694 - mcl1+, the Schizosaccharomyces pombe homologue of CTF4, is important for chromosome replication, cohesion, and segregation.

Williams DR et al. Eukaryot Cell 2002 Oct;1(5):758-73

PMID:17043360 - Interactions between the RNA interference effector protein Ago1 and 14-3-3 proteins: consequences for cell cycle progression.

Stoica C et al. J Biol Chem 2006 Dec 08;281(49):37646-51

PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.

Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7

PMID:22990236 - Hrp3 controls nucleosome positioning to suppress non-coding transcription in eu- and heterochromatin.

Shim YS et al. EMBO J 2012 Nov 28;31(23):4375-87

PMID:31719112 - Checkpoint Regulation of Nuclear Tos4 Defines S Phase Arrest in Fission Yeast.

Kim SM et al. G3 (Bethesda) 2020 Jan 07;10(1):255-266

PMID:24790095 - Characterization of the roles of Blt1p in fission yeast cytokinesis.

Goss JW et al. Mol Biol Cell 2014 Jul 01;25(13):1946-57

PMID:35082773 - Phosphoinositide-Dependent Protein Kinases Regulate Cell Cycle Progression Through the SAD Kinase Cdr2 in Fission Yeast.

Liu K et al. Front Microbiol 2021;12:807148

PMID:17531813 - Cdc18 enforces long-term maintenance of the S phase checkpoint by anchoring the Rad3-Rad26 complex to chromatin.

Hermand D et al. Mol Cell 2007 May 25;26(4):553-63

PMID:10090724 - Association of Chk1 with 14-3-3 proteins is stimulated by DNA damage.

Chen L et al. Genes Dev 1999 Mar 15;13(6):675-85

PMID:19474792 - Polar gradients of the DYRK-family kinase Pom1 couple cell length with the cell cycle.

Martin SG et al. Nature 2009 Jun 11;459(7248):852-6

PMID:28545058 - A systematic genomic screen implicates nucleocytoplasmic transport and membrane growth in nuclear size control.

Kume K et al. PLoS Genet 2017 May;13(5):e1006767

PMID:1500423 - cdc25 is a nuclear protein expressed constitutively throughout the cell cycle in nontransformed mammalian cells.

Girard F et al. J Cell Biol 1992 Aug;118(4):785-94

PMID:23185032 - Nonmedially assembled F-actin cables incorporate into the actomyosin ring in fission yeast.

Huang J et al. J Cell Biol 2012 Nov 26;199(5):831-47

PMID:9832516 - Suppressors of cdc25p overexpression identify two pathways that influence the G2/M checkpoint in fission yeast.

Forbes KC et al. Genetics 1998 Dec;150(4):1361-75

PMID:15629716 - Inactivation of the Cdc25 phosphatase by the stress-activated Srk1 kinase in fission yeast.

López-Avilés S et al. Mol Cell 2005 Jan 07;17(1):49-59

PMID:9108295 - The Schizosaccharomyces pombe cdc6 gene encodes the catalytic subunit of DNA polymerase delta.

Iino Y et al. Mol Gen Genet 1997 Mar 18;254(1):93-7

PMID:28272970 - Wee1 and Cdc25: Tools, pathways, mechanisms, questions.

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PMID:15128870 - A role for the Cdc14-family phosphatase Flp1p at the end of the cell cycle in controlling the rapid degradation of the mitotic inducer Cdc25p in fission yeast.

Esteban V et al. J Cell Sci 2004 May 15;117(Pt 12):2461-8

PMID:8163491 - ntf1+ encodes a 6-cysteine zinc finger-containing transcription factor that regulates the nmt1 promoter in fission yeast.

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PMID:38228139 - Live-cell imaging defines a threshold in CDK activity at the G2/M transition.

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PMID:23349808 - Fission yeast Nod1 is a component of cortical nodes involved in cell size control and division site placement.

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PMID:2544292 - Involvement of a type 1 protein phosphatase encoded by bws1+ in fission yeast mitotic control.

Booher R et al. Cell 1989 Jun 16;57(6):1009-16

PMID:22119525 - SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast.

Singh NS et al. Curr Biol 2011 Dec 06;21(23):1968-78

PMID:9843577 - The cdr2(+) gene encodes a regulator of G2/M progression and cytokinesis in Schizosaccharomyces pombe.

Breeding CS et al. Mol Biol Cell 1998 Dec;9(12):3399-415

PMID:23986474 - Mutation of a conserved residue enhances the sensitivity of analogue-sensitised kinases to generate a novel approach to the study of mitosis in fission yeast.

Tay YD et al. J Cell Sci 2013 Nov 01;126(Pt 21):5052-61

PMID:10101168 - The role of nucleotide binding and hydrolysis in the function of the fission yeast cdc18(+) gene product.

DeRyckere D et al. Genetics 1999 Apr;151(4):1445-57

PMID:1699136 - Distinct nuclear and spindle pole body population of cyclin-cdc2 in fission yeast.

Alfa CE et al. Nature 1990 Oct 18;347(6294):680-2

PMID:8437586 - Mutational analysis of the fission yeast p34cdc2 protein kinase gene.

MacNeill SA et al. Mol Gen Genet 1993 Jan;236(2-3):415-26

PMID:8838655 - Fission yeast Nda1 and Nda4, MCM homologs required for DNA replication, are constitutive nuclear proteins.

Okishio N et al. J Cell Sci 1996 Feb;109 ( Pt 2):319-26

PMID:37463585 - The fission yeast cell size control system integrates pathways measuring cell surface area, volume, and time.

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PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.

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PMID:30806623 - Kinesin-6 regulates cell-size-dependent spindle elongation velocity to keep mitosis duration constant in fission yeast.

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PMID:7217015 - Isolation of cell size mutants of a fission yeast by a new selective method: characterization of mutants and implications for division control mechanisms.

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PMID:11029045 - A role for the START gene-specific transcription factor complex in the inactivation of cyclin B and Cut2 destruction.

Tournier S et al. Mol Biol Cell 2000 Oct;11(10):3411-24

PMID:26527280 - Robust Ordering of Anaphase Events by Adaptive Thresholds and Competing Degradation Pathways.

Kamenz J et al. Mol Cell 2015 Nov 05;60(3):446-59

PMID:25081204 - Negative feedback regulation of calcineurin-dependent Prz1 transcription factor by the CaMKK-CaMK1 axis in fission yeast.

Cisneros-Barroso E et al. Nucleic Acids Res 2014 Sep;42(15):9573-87

PMID:17804800 - Mei4p coordinates the onset of meiosis I by regulating cdc25+ in fission yeast.

Murakami-Tonami Y et al. Proc Natl Acad Sci U S A 2007 Sep 11;104(37):14688-93

PMID:1464318 - Pyp3 PTPase acts as a mitotic inducer in fission yeast.

Millar JB et al. EMBO J 1992 Dec;11(13):4933-41

PMID:9693370 - Mutational effect of fission yeast polalpha on cell cycle events.

Bhaumik D et al. Mol Biol Cell 1998 Aug;9(8):2107-23

PMID:29361524 - F-box proteins Pof3 and Pof1 regulate Wee1 degradation and mitotic entry in fission yeast.

Qiu C et al. J Cell Sci 2018 Feb 02;131(3)

PMID:12135745 - Cmk2, a novel serine/threonine kinase in fission yeast.

Alemany V et al. FEBS Lett 2002 Jul 31;524(1-3):79-86

PMID:2245912 - stf1: non-wee mutations epistatic to cdc25 in the fission yeast Schizosaccharomyces pombe.

Hudson JD et al. Genetics 1990 Oct;126(2):309-15

PMID:22806395 - Carboxy-terminal phosphorylation sites in Cdc25 contribute to enforcement of the DNA damage and replication checkpoints in fission yeast.

Frazer C et al. Curr Genet 2012 Aug;58(4):217-34

PMID:7657164 - Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast.

Millar JB et al. Genes Dev 1995 Sep 01;9(17):2117-30

PMID:8497322 - Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

Walworth N et al. Nature 1993 May 27;363(6427):368-71

PMID:3442828 - Isolation of a novel type of mutation in the mitotic control of Schizosaccharomyces pombe whose phenotypic expression is dependent on the genetic background and nutritional environment.

Ogden JE et al. Curr Genet 1986;10(7):509-14

PMID:25492408 - Meiotic nuclear movements in fission yeast are regulated by the transcription factor Mei4 downstream of a Cds1-dependent replication checkpoint pathway.

Ruan K et al. Genes Cells 2015 Mar;20(3):160-72

PMID:19487457 - The S. pombe mitotic regulator Cut12 promotes spindle pole body activation and integration into the nuclear envelope.

Tallada VA et al. J Cell Biol 2009 Jun 01;185(5):875-88

PMID:34085220 - Highly Synchronous Mitotic Progression in Schizosaccharomyces pombe Upon Relief of Transient Cdc2-asM17 Inhibition.

Singh P et al. Methods Mol Biol 2021;2329:123-142

PMID:9383051 - Mcs4, a two-component system response regulator homologue, regulates the Schizosaccharomyces pombe cell cycle control.

Cottarel G Genetics 1997 Nov;147(3):1043-51

PMID:20231270 - Schizosaccharomyces pombe Dss1p is a DNA damage checkpoint protein that recruits Rad24p, Cdc25p, and Rae1p to DNA double-strand breaks.

Selvanathan SP et al. J Biol Chem 2010 May 07;285(19):14122-33

PMID:16950131 - Phospho-regulation of the Cdc14/Clp1 phosphatase delays late mitotic events in S. pombe.

Wolfe BA et al. Dev Cell 2006 Sep;11(3):423-30

PMID:3955656 - cdc25+ functions as an inducer in the mitotic control of fission yeast.

Russell P et al. Cell 1986 Apr 11;45(1):145-53

PMID:2665944 - Regulation of p34cdc2 protein kinase during mitosis.

Moreno S et al. Cell 1989 Jul 28;58(2):361-72

PMID:8292390 - A novel mutation involved in the mitotic checkpoint in the fission yeast Schizosaccharomyces pombe.

Ishiguro J et al. Jpn J Genet 1993 Aug;68(4):265-76

PMID:8521500 - p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase.

Correa-Bordes J et al. Cell 1995 Dec 15;83(6):1001-9

PMID:20805322 - The mitosis-to-interphase transition is coordinated by cross talk between the SIN and MOR pathways in Schizosaccharomyces pombe.

Ray S et al. J Cell Biol 2010 Sep 06;190(5):793-805

PMID:9923681 - Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein.

Lopez-Girona A et al. Nature 1999 Jan 14;397(6715):172-5

PMID:17409062 - Suppression of the Schizosaccharomyces pombe cut12.1 cell-cycle defect by mutations in cdc25 and genes involved in transcriptional and translational control.

Tallada VA et al. Genetics 2007 May;176(1):73-83

PMID:3453113 - The mitotic inducer nim1+ functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis.

Russell P et al. Cell 1987 May 22;49(4):569-76

PMID:15297457 - On the slowing of S phase in response to DNA damage in fission yeast.

Kumar S et al. J Biol Chem 2004 Oct 15;279(42):43574-80

PMID:15302827 - The forkhead transcription factor Fkh2 regulates the cell division cycle of Schizosaccharomyces pombe.

Bulmer R et al. Eukaryot Cell 2004 Aug;3(4):944-54

PMID:20639859 - 14-3-3gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage.

Kasahara K et al. EMBO J 2010 Aug 18;29(16):2802-12

PMID:32062975 - Phosphoproteomics Reveals Novel Targets and Phosphoprotein Networks in Cell Cycle Mediated by Dsk1 Kinase.

Wu M et al. J Proteome Res 2020 Apr 03;19(4):1776-1787

PMID:9154809 - A novel mutant allele of Schizosaccharomyces pombe rad26 defective in monitoring S-phase progression to prevent premature mitosis.

Uchiyama M et al. Mol Cell Biol 1997 Jun;17(6):3103-15

PMID:33008060 - Caffeine Stabilises Fission Yeast Wee1 in a Rad24-Dependent Manner but Attenuates Its Expression in Response to DNA Damage.

Alao JP et al. Microorganisms 2020 Sep 30;8(10)

PMID:9001228 - A fission yeast homolog of CDC20/p55CDC/Fizzy is required for recovery from DNA damage and genetically interacts with p34cdc2.

Matsumoto T Mol Cell Biol 1997 Feb;17(2):742-50

PMID:7501024 - Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast.

Shiozaki K et al. Nature 1995 Dec 14;378(6558):739-43

PMID:22912829 - Response to arsenate treatment in Schizosaccharomyces pombe and the role of its arsenate reductase activity.

Salgado A et al. PLoS One 2012;7(8):e43208

PMID:28103117 - Wee1 and Cdc25 are controlled by conserved PP2A-dependent mechanisms in fission yeast.

Lucena R et al. Cell Cycle 2017 Mar 04;16(5):428-435

PMID:39705284 - Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast.

Bérard M et al. PLoS Biol 2024 Dec 20;22(12):e3002963

PMID:11809834 - Fission yeast F-box protein Pof3 is required for genome integrity and telomere function.

Katayama S et al. Mol Biol Cell 2002 Jan;13(1):211-24

PMID:1944266 - The fission yeast dis3+ gene encodes a 110-kDa essential protein implicated in mitotic control.

Kinoshita N et al. Mol Cell Biol 1991 Dec;11(12):5839-47

PMID:12482912 - Regulation of meiotic progression by the meiosis-specific checkpoint kinase Mek1 in fission yeast.

Pérez-Hidalgo L et al. J Cell Sci 2003 Jan 15;116(Pt 2):259-71

PMID:23297348 - Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase.

Chen JS et al. Mol Cell Proteomics 2013 May;12(5):1074-86

PMID:26031557 - Loss of kinesin-14 results in aneuploidy via kinesin-5-dependent microtubule protrusions leading to chromosome cut.

Syrovatkina V et al. Nat Commun 2015 Jun 02;6:7322

PMID:29996109 - Quantitative Phosphoproteomics Reveals the Signaling Dynamics of Cell-Cycle Kinases in the Fission Yeast Schizosaccharomyces pombe.

Swaffer MP et al. Cell Rep 2018 Jul 10;24(2):503-514

PMID:22681890 - Hierarchical modularity and the evolution of genetic interactomes across species.

Ryan CJ et al. Mol Cell 2012 Jun 08;46(5):691-704

PMID:20736315 - Specific replication origins promote DNA amplification in fission yeast.

Kiang L et al. J Cell Sci 2010 Sep 15;123(Pt 18):3047-51

PMID:28645196 - Antagonistic regulation of cyclin expression by the bZIP transcription factors Pcr1 and Atf1 during G2/M transition.

Bandyopadhyay S et al. FEMS Microbiol Lett 2017 Aug 01;364(14)

PMID:15917811 - Polo kinase links the stress pathway to cell cycle control and tip growth in fission yeast.

Petersen J et al. Nature 2005 May 26;435(7041):507-12

PMID:19330768 - Tubulin heterodimers remain functional for one cell cycle after the inactivation of tubulin-folding cofactor D in fission yeast cells.

Fedyanina OS et al. Yeast 2009 Apr;26(4):235-47

PMID:35354597 - Quantitative analysis of nuclear pore complex organization in Schizosaccharomyces pombe .

Varberg JM et al. Life Sci Alliance 2022 Jul;5(7)

PMID:15265986 - The Clp1p/Flp1p phosphatase ensures completion of cytokinesis in response to minor perturbation of the cell division machinery in Schizosaccharomyces pombe.

Mishra M et al. J Cell Sci 2004 Aug 01;117(Pt 17):3897-910

PMID:32612670 - Caffeine as a tool for investigating the integration of Cdc25 phosphorylation, activity and ubiquitin-dependent degradation in Schizosaccharomyces pombe .

Alao JP et al. Cell Div 2020;15:10

PMID:38269097 - Rapamycin-sensitive mechanisms confine the growth of fission yeast below the temperatures detrimental to cell physiology.

Morozumi Y et al. iScience 2024 Jan 19;27(1):108777

PMID:22561704 - Regulation of cell cycle and stress responses under nitrosative stress in Schizosaccharomyces pombe.

Majumdar U et al. Free Radic Biol Med 2012 Jun 1;52(11-12):2186-200

PMID:26869222 - Nuclear envelope expansion is crucial for proper chromosomal segregation during a closed mitosis.

Takemoto A et al. J Cell Sci 2016 Mar 15;129(6):1250-9

PMID:24508166 - Dueling kinases regulate cell size at division through the SAD kinase Cdr2.

Deng L et al. Curr Biol 2014 Feb 17;24(4):428-33

PMID:29813053 - Specific detection of fission yeast primary septum reveals septum and cleavage furrow ingression during early anaphase independent of mitosis completion.

G Cortés JC et al. PLoS Genet 2018 May;14(5):e1007388

PMID:15857958 - Roles of Pdk1p, a fission yeast protein related to phosphoinositide-dependent protein kinase, in the regulation of mitosis and cytokinesis.

Bimbó A et al. Mol Biol Cell 2005 Jul;16(7):3162-75

PMID:27268234 - Both H4K20 mono-methylation and H3K56 acetylation mark transcription-dependent histone turnover in fission yeast.

Yang H et al. Biochem Biophys Res Commun 2016 Aug 05;476(4):515-521

PMID:12815070 - Physical and functional interactions between polo kinase and the spindle pole component Cut12 regulate mitotic commitment in S. pombe.

MacIver FH et al. Genes Dev 2003 Jun 15;17(12):1507-23

PMID:11739790 - Two related kinesins, klp5+ and klp6+, foster microtubule disassembly and are required for meiosis in fission yeast.

West RR et al. Mol Biol Cell 2001 Dec;12(12):3919-32

PMID:8319772 - In vivo phosphorylation, mitotic behavior, and nuclear binding of the catalytic subunit of DNA polymerase alpha in fission yeast.

Bouvier D et al. Exp Cell Res 1993 Jul;207(1):41-7

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