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protein coding gene - SPAC25A8.03c - mitochondrial respiratory complex assembly factor/arginine methyltransferase, human NDUFAF7 ortholog

Gene summary

Systematic ID
SPAC25A8.03c
Product
mitochondrial respiratory complex assembly factor/arginine methyltransferase, human NDUFAF7 ortholog
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
SPAC3C7.15c
UniProt ID
O14138
ORFeome ID
01/01A11
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome I: 2096162..2098018 reverse strand

Annotation

GO biological process

GO:0033108 - mitochondrial respiratory chain complex assembly

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GO cellular component

GO:0005739 - mitochondrion

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GO molecular function

GO:0035243 - protein-arginine omega-N symmetric methyltransferase activity

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Quantitative gene expression

PBO:0011963 - RNA level

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Single locus phenotype

FYPO:0009007 - decreased vegetative cell population viability

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Genotypes:

FYPO:0004163 - increased viability upon glucose starvation

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Genotypes:

FYPO:0009032 - resistance to bortezomib

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Genotypes:

FYPO:0001583 - resistance to lithium

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Genotypes:

FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

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Genotypes:

FYPO:0000725 - resistance to methyl methanesulfonate

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Genotypes:

FYPO:0009039 - resistance to potassium chloride

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Genotypes:

FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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Genotypes:

FYPO:0003383 - resistance to tert-butyl hydroperoxide

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Genotypes:

FYPO:0007928 - sensitive to ethylenediaminetetraacetic acid

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Genotypes:

FYPO:0000089 - sensitive to methyl methanesulfonate

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Genotypes:

FYPO:0002060 - viable vegetative cell population

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Genotypes:

FYPO:0002177 - viable vegetative cell with normal cell morphology

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Genotypes:

Taxonomic conservation

PBO:0011067 - conserved in bacteria

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

IDNameInterPro nameDB name
PF02636Methyltransf_28NDUFAF7PFAM
SSF53335S-adenosyl-L-methionine-dependent methyltransferasesSAM-dependent_MTases_sfSUPERFAMILY
G3DSA:3.40.50.12710NDUFAF7_sfGENE3D
PTHR12049PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIALNDUFAF7PANTHER

Orthologs

References / Literature

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12
PMID:23163955 - Analysis of stress-induced duplex destabilization (SIDD) properties of replication origins, genes and intergenes in the fission yeast, Schizosaccharomyces pombe.
Yadav MP et al. BMC Res Notes 2012 Nov 19;5:643
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:34984977 - Functional profiling of long intergenic non-coding RNAs in fission yeast.
Rodriguez-Lopez M et al. Elife 2022 Jan 05;11
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7