protein coding gene - mug105 (SPAC25H1.04) - K48-linkage specific deubiquitinase, implicated in DNA damage response

Gene summary

Standard name

mug105

Systematic ID

SPAC25H1.04

Product

K48-linkage specific deubiquitinase, implicated in DNA damage response

Organism

Schizosaccharomyces pombe (fission yeast)

Synonyms

zup1

UniProt ID

O13979

ORFeome ID

08/08G12

Characterisation status

conserved unknown

Feature type

mRNA gene

Genomic location

chromosome I: 2529075..2529901 forward strand

Annotation

Protein features

Orthologs

• ZUP1 (HGNC:21224) Homo sapiens

References / Literature

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:29476094 - A family of unconventional deubiquitinases with modular chain specificity determinants.

Hermanns T et al. Nat Commun 2018 Feb 23;9(1):799

PMID:12161753 - The transcriptional program of meiosis and sporulation in fission yeast.

Mata J et al. Nat Genet 2002 Sep;32(1):143-7

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:22146723 - Systematic localization study on novel proteins encoded by meiotically up-regulated ORFs in fission yeast.

Ikebe C et al. Biosci Biotechnol Biochem 2011;75(12):2364-70

PMID:35058438 - A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family.

Hermanns T et al. Nat Commun 2022 Jan 20;13(1):401

PMID:16537923 - Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast.

Todd BL et al. Mol Cell Biol 2006 Apr;26(7):2817-31

PMID:33313903 - Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast.

Rubio A et al. Nucleic Acids Res 2021 Jan 11;49(1):383-399

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:34250083 - Barcode sequencing and a high-throughput assay for chronological lifespan uncover ageing-associated genes in fission yeast.

Romila CA et al. Microb Cell 2021 Jul 05;8(7):146-160

PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.

Rodríguez-López M et al. Elife 2023 Oct 03;12