protein coding gene - rfc3 (SPAC27E2.10c) - DNA replication factor C complex subunit Rfc3

Gene summary

Standard name

rfc3

Systematic ID

SPAC27E2.10c

Product

DNA replication factor C complex subunit Rfc3

Organism

Schizosaccharomyces pombe (fission yeast)

Synonyms

SPAPJ698.01c

UniProt ID

O14003

ORFeome ID

39/39E11

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome I: 4034145..4035832 reverse strand

Annotation

Protein features

Orthologs

• RFC5 (HGNC:9973) Homo sapiens
• rfc3 (SJAG_02182) Schizosaccharomyces japonicus
• RFC3 (YNL290W) Saccharomyces cerevisiae

References / Literature

PMID:10588638 - Replication factor C3 of Schizosaccharomyces pombe, a small subunit of replication factor C complex, plays a role in both replication and damage checkpoints.

Shimada M et al. Mol Biol Cell 1999 Dec;10(12):3991-4003

PMID:24713849 - Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex.

Egan ED et al. RNA 2014 Jun;20(6):867-81

GO_REF:0000051 - S. pombe keyword mapping

PMID:20885790 - Critical functions of Rpa3/Ssb3 in S-phase DNA damage responses in fission yeast.

Cavero S et al. PLoS Genet 2010 Sep 23;6(9):e1001138

PMID:10704216 - In vitro reconstitution of the Schizosaccharomyces pombe alternative excision repair pathway.

Alleva JL et al. Biochemistry 2000 Mar 14;39(10):2659-66

PMID:24013502 - Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries.

Wang J et al. Genes Dev 2013 Sep 01;27(17):1886-902

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:26368543 - Critical Function of γH2A in S-Phase.

Mejia-Ramirez E et al. PLoS Genet 2015 Sep;11(9):e1005517

PMID:16040599 - Contrasting effects of Elg1-RFC and Ctf18-RFC inactivation in the absence of fully functional RFC in fission yeast.

Kim J et al. Nucleic Acids Res 2005;33(13):4078-89

PMID:26670050 - Regulation of mRNA Levels by Decay-Promoting Introns that Recruit the Exosome Specificity Factor Mmi1.

Kilchert C et al. Cell Rep 2015 Dec 22;13(11):2504-2515

GO_REF:0000036 - Manual annotations that require more than one source of functional data to support the assignment of the associated GO term

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36

PMID:30321377 - Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome.

Telekawa C et al. Nucleic Acids Res 2018 Nov 30;46(21):11169-11183

GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.

PMID:10748208 - Fidelity of eucaryotic DNA polymerase delta holoenzyme from Schizosaccharomyces pombe.

Chen X et al. J Biol Chem 2000 Jun 09;275(23):17677-82

PMID:10794172 - The Schizosaccharomyces pombe rfc3+ gene encodes a homologue of the human hRFC36 and Saccharomyces cerevisiae Rfc3 subunits of replication factor C.

Gray FC et al. Curr Genet 2000 Mar;37(3):159-67

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7

GO_REF:0000002 - Comments

GO_REF:0000033 - Annotation inferences using phylogenetic trees

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6