protein coding gene - tbp1 (SPAC29E6.08) - TATA-binding protein (TBP)

Gene summary

Standard name

tbp1

Systematic ID

SPAC29E6.08

Product

TATA-binding protein (TBP)

Organism

Schizosaccharomyces pombe (fission yeast)

Synonyms

tdf1, tbp, SPAC30.12

UniProt ID

P17871

ORFeome ID

43/43G03

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome I: 4415479..4417151 forward strand

Annotation

Protein features

Orthologs

• TBP (HGNC:11588) Homo sapiens
• TBPL2 (HGNC:19841) Homo sapiens
• tbp1 (SJAG_00421) Schizosaccharomyces japonicus
• SPT15 (YER148W) Saccharomyces cerevisiae

References / Literature

PMID:11279037 - Two WD repeat-containing TATA-binding protein-associated factors in fission yeast that suppress defects in the anaphase-promoting complex.

Mitsuzawa H et al. J Biol Chem 2001 May 18;276(20):17117-24

GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.

PMID:19111658 - HP1 proteins form distinct complexes and mediate heterochromatic gene silencing by nonoverlapping mechanisms.

Motamedi MR et al. Mol Cell 2008 Dec 26;32(6):778-90

PMID:33771877 - RNA polymerase backtracking results in the accumulation of fission yeast condensin at active genes.

Rivosecchi J et al. Life Sci Alliance 2021 Jun;4(6)

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:30355493 - Expanded Interactome of the Intrinsically Disordered Protein Dss1.

Schenstrøm SM et al. Cell Rep 2018 Oct 23;25(4):862-870

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:2210373 - Cloning of the Schizosaccharomyces pombe TFIID gene reveals a strong conservation of functional domains present in Saccharomyces cerevisiae TFIID.

Hoffmann A et al. Genes Dev 1990 Jul;4(7):1141-8

PMID:15182371 - Mediator is required for activated transcription in a Schizosaccharomyces pombe in vitro system.

Tamayo E et al. Eur J Biochem 2004 Jun;271(12):2561-72

PMID:28060464 - RNA polymerase II components and Rrn7 form a preinitiation complex on the HomolD box to promote ribosomal protein gene expression in Schizosaccharomyces pombe.

Montes M et al. FEBS J 2017 Feb;284(4):615-633

PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:29214404 - The 19S proteasome regulates subtelomere silencing and facultative heterochromatin formation in fission yeast.

Seo HD et al. Curr Genet 2018 Jun;64(3):741-752

PMID:28947618 - Sde2 is an intron-specific pre-mRNA splicing regulator activated by ubiquitin-like processing.

Thakran P et al. EMBO J 2018 Jan 04;37(1):89-101

PMID:20018856 - Involvement of the spliceosomal U4 small nuclear RNA in heterochromatic gene silencing at fission yeast centromeres.

Chinen M et al. J Biol Chem 2010 Feb 19;285(8):5630-8

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36

PMID:9092673 - An immunoaffinity purified Schizosaccharomyces pombe TBP-containing complex directs correct initiation of the S.pombe rRNA gene promoter.

Chen L et al. Nucleic Acids Res 1997 Apr 15;25(8):1633-40

PMID:33313903 - Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast.

Rubio A et al. Nucleic Acids Res 2021 Jan 11;49(1):383-399

PMID:12565823 - The kic1 kinase of schizosaccharomyces pombe is a CLK/STY orthologue that regulates cell-cell separation.

Tang Z et al. Exp Cell Res 2003 Feb 01;283(1):101-15

PMID:34496258 - Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription.

Heo DH et al. Cell Rep 2021 Sep 07;36(10):109671

PMID:27738016 - RNA interference is essential for cellular quiescence.

Roche B et al. Science 2016 Nov 11;354(6313)

PMID:11972332 - Identification of histone H4-like TAF in Schizosaccharomyces pombe as a protein that interacts with WD repeat-containing TAF.

Mitsuzawa H et al. Nucleic Acids Res 2002 May 01;30(9):1952-8

PMID:11968006 - Human papillomavirus-16 E7 protein inhibits the DNA interaction of the TATA binding transcription factor.

Maldonado E et al. J Cell Biochem 2002;85(4):663-9

PMID:2197558 - Striking conservation of TFIID in Schizosaccharomyces pombe and Saccharomyces cerevisiae.

Fikes JD et al. Nature 1990 Jul 19;346(6281):291-4

PMID:30076928 - Point mutation A394E in the central intrinsic disordered region of Rna14 leads to chromosomal instability in fission yeast.

Sonkar A et al. Int J Biol Macromol 2018 Nov;119:785-791

PMID:30810475 - Early splicing functions of fission yeast Prp16 and its unexpected requirement for gene Silencing is governed by intronic features.

Vijayakumari D et al. RNA Biol 2019 Jun;16(6):754-769

PMID:15616156 - Tfg3, a subunit of the general transcription factor TFIIF in Schizosaccharomyces pombe, functions under stress conditions.

Kimura M et al. Nucleic Acids Res 2004;32(22):6706-15

PMID:18362178 - Dissection of the essential steps for condensin accumulation at kinetochores and rDNAs during fission yeast mitosis.

Nakazawa N et al. J Cell Biol 2008 Mar 24;180(6):1115-31

PMID:26537787 - Targeting of SUMO substrates to a Cdc48-Ufd1-Npl4 segregase and STUbL pathway in fission yeast.

Køhler JB et al. Nat Commun 2015 Nov 05;6:8827

PMID:26730850 - Prp4 Kinase Grants the License to Splice: Control of Weak Splice Sites during Spliceosome Activation.

Eckert D et al. PLoS Genet 2016 Jan;12(1):e1005768

PMID:24081329 - Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay.

Grenier St-Sauveur V et al. Mol Cell Biol 2013 Dec;33(23):4718-31

PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.

Strachan J et al. J Cell Sci 2023 Dec 01;136(23)

PMID:8303296 - RNA polymerase II initiation factor interactions and transcription start site selection.

Li Y et al. Science 1994 Feb 11;263(5148):805-7

PMID:12682361 - The fission yeast TFIIB-related factor limits RNA polymerase III to a TATA-dependent pathway of TBP recruitment.

Huang Y et al. Nucleic Acids Res 2003 Apr 15;31(8):2108-16

PMID:22540037 - Predicting the fission yeast protein interaction network.

Pancaldi V et al. G3 (Bethesda) 2012 Apr;2(4):453-67

PMID:26257282 - Interaction between TBP and Condensin Drives the Organization and Faithful Segregation of Mitotic Chromosomes.

Iwasaki O et al. Mol Cell 2015 Sep 03;59(5):755-67

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7