PomBase - protein coding gene - rim1 (SPAC2F3.04c) - mitochondrial single-stranded DNA binding protein Rim1 - The Schizosaccharomyces pombe genome database

Protein features

ID	Name	InterPro name	DB name
PF00436	SSB	Primosome_PriB/ssb	PFAM
cd04496	SSB_OBF	Primosome_PriB/ssb	CDD
PS50935	SSB	Primosome_PriB/ssb	PROSITE_PROFILES
SSF50249	Nucleic acid-binding proteins	NA-bd_OB-fold	SUPERFAMILY
G3DSA:2.40.50.140		NA-bd_OB-fold	GENE3D
mobidb-lite-Disorder	disorder_prediction		MOBIDB-Disorder
mobidb-lite-Polyampholyte	disorder_prediction		MOBIDB-Polyampholyte

References / Literature

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).: Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:21511999 - Comparative functional genomics of the fission yeasts.: Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:31563844 - The roles of fission yeast exonuclease 5 in nuclear and mitochondrial genome stability.: Sparks JL et al. DNA Repair (Amst) 2019 Nov;83:102720
PMID:21340088 - Microarray-based target identification using drug hypersensitive fission yeast expressing ORFeome.: Arita Y et al. Mol Biosyst 2011 May;7(5):1463-72
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.: Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:36408920 - UniProt: the Universal Protein Knowledgebase in 2023.: UniProt Consortium Nucleic Acids Res 2023 Jan 06;51(D1):D523-D531
PMID:22540037 - Predicting the fission yeast protein interaction network.: Pancaldi V et al. G3 (Bethesda) 2012 Apr;2(4):453-67
PMID:27611590 - Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity.: McDonald KR et al. PLoS Genet 2016 Sep;12(9):e1006238
PMID:30099677 - Genome-wide evidences of bisphenol a toxicity using Schizosaccharomyces pombe.: Kim DM et al. Arch Pharm Res 2018 Aug;41(8):830-837
PMID:23779158 - The proteasome factor Bag101 binds to Rad22 and suppresses homologous recombination.: Saito Y et al. Sci Rep 2013;3:2022
PMID:30355493 - Expanded Interactome of the Intrinsically Disordered Protein Dss1.: Schenstrøm SM et al. Cell Rep 2018 Oct 23;25(4):862-870
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.: Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.: Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.: Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:31883795 - Positioning Heterochromatin at the Nuclear Periphery Suppresses Histone Turnover to Promote Epigenetic Inheritance.: Holla S et al. Cell 2020 Jan 09;180(1):150-164.e15
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.: Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs
PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.: Skribbe M et al. Mol Cell 2025 Feb 19;
PMID:27984744 - Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs.: Joh RI et al. Mol Cell 2016 Dec 15;64(6):1088-1101
PMID:17312948 - Gene structure and biochemical characterization of mitochondrial single-stranded DNA binding protein from Schizosaccharomyces pombe.: Nishio M et al. DNA Seq 2006 Aug;17(4):287-91
PMID:30617184 - A stable tetramer is not the only oligomeric state that mitochondrial single-stranded DNA binding proteins can adopt.: Singh SP et al. J Biol Chem 2019 Mar 15;294(11):4137-4144
PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.: Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7

protein coding gene - rim1 (SPAC2F3.04c) - mitochondrial single-stranded DNA binding protein Rim1

Gene summary

Annotation

Disease association

MONDO:0008135 - optic atrophy 13 with retinal and foveal abnormalities

GO biological process

GO:0090297 - positive regulation of mitochondrial DNA replication

GO cellular component

GO:0042645 - mitochondrial nucleoid

GO:0005739 - mitochondrion

GO molecular function

GO:0008047 - enzyme activator activity

GO:0003697 - single-stranded DNA binding

Modification

MOD:00046 - O-phospho-L-serine

Protein sequence feature

SO:0001808 - mitochondrial_targeting_signal

Qualitative gene expression

PomGeneEx:0000012 - RNA level decreased

Quantitative gene expression

PBO:0006310 - protein level

PBO:0011963 - RNA level

Single locus phenotype

FYPO:0002111 - inviable tapered vegetative cell

FYPO:0002061 - inviable vegetative cell population

FYPO:0006680 - sensitive to bisphenol A

Subunit composition

PBO:0015242 - homomeric(4)

Taxonomic conservation

PBO:0011067 - conserved in bacteria

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

Orthologs

References / Literature