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protein coding gene - ceo2 (SPAC3A12.02) - mitochondrial inorganic diphosphatase Ceo2

Gene summary

Standard name
ceo2
Systematic ID
SPAC3A12.02
Product
mitochondrial inorganic diphosphatase Ceo2
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
P87118
ORFeome ID
15/15E03
Characterisation status
conserved unknown
Feature type
mRNA gene
Genomic location
chromosome I: 1421818..1422972 forward strand

Annotation

GO cellular component

GO:0005739 - mitochondrion

References:

GO molecular function

GO:0004427 - inorganic diphosphate phosphatase activity

References:

GO:0000287 - magnesium ion binding

References:

Qualitative gene expression

PomGeneEx:0000011 - RNA level increased

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002111 - inviable tapered vegetative cell

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0001420 - normal vegetative cell population growth rate

References:

Genotypes:

FYPO:0002058 - viable cell population

References:

Genotypes:

FYPO:0002104 - viable vegetative cell with normal cell shape

References:

Genotypes:

Subunit composition

PBO:0015212 - homomeric(2)

Taxonomic conservation

PBO:0011067 - conserved in bacteria

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

Protein features

IDNameInterPro nameDB name
PF00719PyrophosphatasePyrophosphatasePFAM
cd00412pyrophosphatasePyrophosphataseCDD
PS00387PPASEPROSITE_PATTERNS
G3DSA:3.90.80.10:FF:000007FUNFAM
SSF50324Inorganic pyrophosphatasePyrophosphatase_sfSUPERFAMILY
G3DSA:3.90.80.10Inorganic pyrophosphatasePyrophosphatase_sfGENE3D
PTHR10286INORGANIC PYROPHOSPHATASEPyrophosphatasePANTHER

Orthologs

References / Literature

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:37162093 - Genetic knockdown of genes that are obscure, conserved and essential using CRISPR interference methods in the fission yeast S. pombe.
Ishikawa K et al. J Cell Sci 2023 May 01;136(9)
PMID:36794724 - Cellular responses to long-term phosphate starvation of fission yeast: Maf1 determines fate choice between quiescence and death associated with aberrant tRNA biogenesis.
Garg A et al. Nucleic Acids Res 2023 Apr 24;51(7):3094-3115
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:23163955 - Analysis of stress-induced duplex destabilization (SIDD) properties of replication origins, genes and intergenes in the fission yeast, Schizosaccharomyces pombe.
Yadav MP et al. BMC Res Notes 2012 Nov 19;5:643
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7