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protein coding gene - rpp1 (SPAC3A12.04c) - RNase P and RNase MRP subunit p30, Rpp1

Gene summary

Standard name
rpp1
Systematic ID
SPAC3A12.04c
Product
RNase P and RNase MRP subunit p30, Rpp1
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
P87120
ORFeome ID
43/43B08
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome I: 1424660..1425594 reverse strand

Annotation

GO biological process

GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

References:

GO:0008033 - tRNA processing

References:

GO cellular component

GO:0005655 - nucleolar ribonuclease P complex

References:

GO:0000172 - ribonuclease MRP complex

References:

GO molecular function

GO:0000171 - ribonuclease MRP activity

References:

GO:0004526 - ribonuclease P activity

References:

GO:0003723 - RNA binding

References:

Modification

MOD:01148 - ubiquitinylated lysine

References:

Qualitative gene expression

PomGeneEx:0000019 - protein level decreased

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0002451 - inviable vegetative cell with abnormal cell shape

References:

Genotypes:

Taxonomic conservation

PBO:0011072 - conserved in archaea

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Warnings

PBO:0000108 - frameshifted

References:

PBO:0091326 - I:g.1424709delA

References:

PBO:0000129 - sequence error in genomic data

References:

Protein features

IDNameInterPro nameDB name
PF01876RNase_P_p30RNase_P_p30Pfam
G3DSA:3.20.20.140CATH-Gene3D
SSF89550Pol/histidinol_Pase-likeSUPERFAMILY
PTHR13031RNase_P_p30PANTHER

Orthologs

References / Literature

GO_REF:0000033 - Annotation inferences using phylogenetic trees
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:25401760 - RNase MRP cleaves pre-tRNASer-Met in the tRNA maturation pathway.
Saito Y et al. PLoS One 2014;9(11):e112488
PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.
Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105
PMID:26615217 - Bulk Segregant Analysis Reveals the Genetic Basis of a Natural Trait Variation in Fission Yeast.
Hu W et al. Genome Biol Evol 2015 Nov 27;7(12):3496-510
PMID:6262315 - Partial purification of RNase P from Schizosaccharomyces pombe.
Kline L et al. J Biol Chem 1981 May 25;256(10):5058-63
PMID:20118936 - Schizosaccharomyces pombe genome-wide nucleosome mapping reveals positioning mechanisms distinct from those of Saccharomyces cerevisiae.
Lantermann AB et al. Nat Struct Mol Biol 2010 Feb;17(2):251-7
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.
Strachan J et al. J Cell Sci 2023 Dec 01;136(23)
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83