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protein coding gene - rad55 (SPAC3C7.03c) - DNA recombination mediator, RecA family ATPase Rad55/Rhp55

Gene summary

Standard name
rad55
Systematic ID
SPAC3C7.03c
Product
DNA recombination mediator, RecA family ATPase Rad55/Rhp55
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
rhp55
UniProt ID
O14129
ORFeome ID
40/40C10
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome I: 2066442..2067914 reverse strand

Annotation

Disease association

MONDO:0013253 - breast-ovarian cancer, familial, susceptibility to, 3

References:

MONDO:0013248 - Fanconi anemia complementation group O

References:

GO biological process

GO:0006974 - DNA damage response

References:

GO:0042148 - DNA strand invasion

References:

GO:0000724 - double-strand break repair via homologous recombination

References:

GO:0000707 - meiotic DNA recombinase assembly

References:

GO:0000709 - meiotic joint molecule formation

References:

GO:0007131 - reciprocal meiotic recombination

References:

GO cellular component

GO:0005829 - cytosol

References:

GO:0005634 - nucleus

References:

GO:0033063 - Rad51B-Rad51C-Rad51D-XRCC2 complex

References:

GO:0033065 - Rad51C-XRCC3 complex

References:

GO:0035861 - site of double-strand break

References:

GO molecular function

GO:0005524 - ATP binding

References:

GO:0016887 - ATP hydrolysis activity

References:

GO:0140664 - ATP-dependent DNA damage sensor activity

References:

GO:0008821 - crossover junction DNA endonuclease activity

References:

GO:0000400 - four-way junction DNA binding

References:

GO:0005515 - protein binding

References:

Modification

MOD:00046 - O-phospho-L-serine

References:

Multi-locus phenotype

FYPO:0005453 - abolished break-induced loss of heterozygosity via chromosomal translocation

References:

Genotypes:

FYPO:0005451 - decreased break-induced loss of heterozygosity

References:

Genotypes:

FYPO:0001407 - decreased cell population growth on glucose carbon source

References:

Genotypes:

FYPO:0003912 - decreased double-strand break repair via homologous recombination

References:

Genotypes:

FYPO:0005660 - decreased frequency of meiotic crossover associated with gene conversion

References:

Genotypes:

FYPO:0000185 - decreased gene conversion during vegetative growth

References:

Genotypes:

FYPO:0002485 - decreased intergenic meiotic recombination

References:

Genotypes:

FYPO:0003179 - decreased intragenic meiotic recombination

References:

Genotypes:

FYPO:0000581 - decreased spore germination frequency

References:

Genotypes:

FYPO:0000584 - decreased sporulation frequency

References:

Genotypes:

FYPO:0001355 - decreased vegetative cell population growth

References:

Genotypes:

FYPO:0005452 - increased break-induced loss of heterozygosity

References:

Genotypes:

FYPO:0005659 - increased frequency of meiotic crossover associated with gene conversion

References:

Genotypes:

FYPO:0001840 - increased minichromosome loss during vegetative growth

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0002219 - normal chromosome disjunction at meiosis I

References:

Genotypes:

FYPO:0006420 - normal duration of Rad51 focus presence during meiotic cell cycle

References:

Genotypes:

FYPO:0005657 - normal frequency of meiotic crossover associated with gene conversion

References:

Genotypes:

FYPO:0000085 - sensitive to camptothecin

References:

Genotypes:

FYPO:0000265 - sensitive to DNA damage

References:

Genotypes:

FYPO:0003559 - sensitive to doxorubicin

References:

Genotypes:

FYPO:0000088 - sensitive to hydroxyurea

References:

Genotypes:

FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

References:

Genotypes:

FYPO:0000089 - sensitive to methyl methanesulfonate

References:

Genotypes:

FYPO:0000268 - sensitive to UV during vegetative growth

References:

Genotypes:

FYPO:0001234 - slow vegetative cell population growth

References:

Genotypes:

FYPO:0005455 - telomere assembly at double-strand break site

References:

Genotypes:

Protein features

PBO:0111792 - AAA family ATPase

PBO:0111851 - helix-hairpin-helix

PBO:0111850 - RecA family

Qualitative gene expression

PomGeneEx:0000011 - RNA level increased

References:

PomGeneEx:0000014 - RNA present

References:

Quantitative gene expression

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0003625 - abnormal microtubule cytoskeleton morphology during mitotic interphase

References:

Genotypes:

FYPO:0000059 - abnormal mitotic cell cycle

References:

Genotypes:

FYPO:0000062 - abnormal nuclear morphology during vegetative growth

References:

Genotypes:

FYPO:0005453 - abolished break-induced loss of heterozygosity via chromosomal translocation

References:

Genotypes:

FYPO:0000080 - decreased cell population growth at low temperature

References:

Genotypes:

FYPO:0009075 - decreased cell population growth on fructose carbon source

References:

Genotypes:

FYPO:0000251 - decreased cell population growth on galactose carbon source

References:

Genotypes:

FYPO:0001407 - decreased cell population growth on glucose carbon source

References:

Genotypes:

FYPO:0000684 - decreased cell population growth on glycerol carbon source

References:

Genotypes:

FYPO:0002924 - decreased cell population growth on maltose carbon source

References:

Genotypes:

FYPO:0009099 - decreased cell population growth on mannitol carbon source

References:

Genotypes:

FYPO:0001176 - decreased cell population growth on sucrose carbon source

References:

Genotypes:

FYPO:0009097 - decreased cell population growth on xylose carbon source

References:

Genotypes:

FYPO:0003912 - decreased double-strand break repair via homologous recombination

References:

Genotypes:

FYPO:0005660 - decreased frequency of meiotic crossover associated with gene conversion

References:

Genotypes:

FYPO:0000185 - decreased gene conversion during vegetative growth

References:

Genotypes:

FYPO:0002485 - decreased intergenic meiotic recombination

References:

Genotypes:

FYPO:0003179 - decreased intragenic meiotic recombination

References:

Genotypes:

FYPO:0005388 - decreased number of Rad51 foci during cellular response to ionizing radiation

References:

Genotypes:

FYPO:0000581 - decreased spore germination frequency

References:

Genotypes:

FYPO:0000584 - decreased sporulation frequency

References:

Genotypes:

FYPO:0000158 - DNA content increased during vegetative growth

References:

Genotypes:

FYPO:0001122 - elongated vegetative cell

References:

Genotypes:

FYPO:0005452 - increased break-induced loss of heterozygosity

References:

Genotypes:

FYPO:0005261 - increased cell population growth on galactose carbon source

References:

Genotypes:

FYPO:0009028 - increased cell population growth on proline nitrogen source

References:

Genotypes:

FYPO:0009074 - increased cell population growth on serine nitrogen source

References:

Genotypes:

FYPO:0003584 - increased double-strand break repair via nonhomologous end joining

References:

Genotypes:

FYPO:0001386 - increased haploidization

References:

Genotypes:

FYPO:0007392 - increased loss of disomic chromosome 3

References:

Genotypes:

FYPO:0001840 - increased minichromosome loss during vegetative growth

References:

Genotypes:

FYPO:0000473 - increased mitotic recombination

References:

Genotypes:

FYPO:0001974 - increased number of cells with 1C DNA content

References:

Genotypes:

FYPO:0004557 - increased vegetative cell population growth

References:

Genotypes:

FYPO:0001309 - increased viability in stationary phase

References:

Genotypes:

FYPO:0002151 - inviable spore

References:

Genotypes:

FYPO:0000245 - loss of viability in stationary phase

References:

Genotypes:

FYPO:0001839 - normal minichromosome loss

References:

Genotypes:

FYPO:0003530 - normal S-phase DNA damage checkpoint

References:

Genotypes:

FYPO:0001357 - normal vegetative cell population growth

References:

Genotypes:

FYPO:0000763 - resistance to cadmium

References:

Genotypes:

FYPO:0009068 - resistance to ciclopirox olamine

References:

Genotypes:

FYPO:0009083 - resistance to lithium chloride and methyl methanesulfonate

References:

Genotypes:

FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0009039 - resistance to potassium chloride

References:

Genotypes:

FYPO:0000077 - resistance to rapamycin

References:

Genotypes:

FYPO:0005968 - resistance to sodium chloride

References:

Genotypes:

FYPO:0000327 - resistance to trichostatin A

References:

Genotypes:

FYPO:0001034 - resistance to tunicamycin

References:

Genotypes:

FYPO:0007933 - sensitive to 2,2′-dipyridyl

References:

Genotypes:

FYPO:0001098 - sensitive to 4-nitroquinoline N-oxide

References:

Genotypes:

FYPO:0004325 - sensitive to 5-fluorouracil

References:

Genotypes:

FYPO:0009067 - sensitive to amorolfine

References:

Genotypes:

FYPO:0000095 - sensitive to bleomycin

References:

Genotypes:

FYPO:0001701 - sensitive to bortezomib

References:

Genotypes:

FYPO:0001501 - sensitive to brefeldin A

References:

Genotypes:

FYPO:0000097 - sensitive to caffeine during vegetative growth

References:

Genotypes:

FYPO:0000085 - sensitive to camptothecin

References:

Genotypes:

FYPO:0000102 - sensitive to cisplatin

References:

Genotypes:

FYPO:0000104 - sensitive to cycloheximide

References:

Genotypes:

FYPO:0000799 - sensitive to diamide

References:

Genotypes:

FYPO:0003559 - sensitive to doxorubicin

References:

Genotypes:

FYPO:0000842 - sensitive to ethanol during vegetative growth

References:

Genotypes:

FYPO:0007928 - sensitive to ethylenediaminetetraacetic acid

References:

Genotypes:

FYPO:0000785 - sensitive to formamide

References:

Genotypes:

FYPO:0000088 - sensitive to hydroxyurea

References:

Genotypes:

FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

References:

Genotypes:

FYPO:0009071 - sensitive to itraconazole

References:

Genotypes:

FYPO:0001719 - sensitive to lithium

References:

Genotypes:

FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0006836 - sensitive to magnesium chloride

References:

Genotypes:

FYPO:0009088 - sensitive to magnesium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0000089 - sensitive to methyl methanesulfonate

References:

Genotypes:

FYPO:0000970 - sensitive to mitomycin C

References:

Genotypes:

FYPO:0001214 - sensitive to potassium chloride

References:

Genotypes:

FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0007938 - sensitive to tea tree oil

References:

Genotypes:

FYPO:0000091 - sensitive to thiabendazole

References:

Genotypes:

FYPO:0001457 - sensitive to tunicamycin

References:

Genotypes:

FYPO:0000268 - sensitive to UV during vegetative growth

References:

Genotypes:

FYPO:0003656 - sensitive to vanadate

References:

Genotypes:

FYPO:0005455 - telomere assembly at double-strand break site

References:

Genotypes:

FYPO:0001492 - viable elongated vegetative cell

References:

Genotypes:

FYPO:0001491 - viable vegetative cell

References:

Genotypes:

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

FYPO:0002197 - viable vegetative cell with abnormal cell shape

References:

Genotypes:

Subunit composition

PBO:0015221 - heteromeric(2)

References:

Taxonomic conservation

PBO:0011067 - conserved in bacteria

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

Protein features

IDNameInterPro nameDB name
PS50162RECA_2RecA_ATP-bdPROSITE_PROFILES
SSF52540P-loop containing nucleoside triphosphate hydrolasesP-loop_NTPaseSUPERFAMILY
G3DSA:3.40.50.300P-loop_NTPaseGENE3D
PTHR46239DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51CHR_Repair_MediatorPANTHER
mobidb-lite-Disorderdisorder_predictionMOBIDB-Disorder

Orthologs

References / Literature

PMID:27304859 - Dbl2 Regulates Rad51 and DNA Joint Molecule Metabolism to Ensure Proper Meiotic Chromosome Segregation.
Polakova S et al. PLoS Genet 2016 Jun;12(6):e1006102
PMID:32204793 - Cooperative interactions facilitate stimulation of Rad51 by the Swi5-Sfr1 auxiliary factor complex.
Argunhan B et al. Elife 2020 Mar 24;9
PMID:15802523 - A postsynaptic role for Rhp55/57 that is responsible for cell death in Deltarqh1 mutants following replication arrest in Schizosaccharomyces pombe.
Hope JC et al. Genetics 2005 Jun;170(2):519-31
PMID:21760946 - Identification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombe.
Takeda K et al. PLoS One 2011;6(7):e22021
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:23173672 - Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.
Pan X et al. BMC Genomics 2012 Nov 23;13:662
PMID:25701403 - Two fission yeast high mobility group box proteins in the maintenance of genomic integrity following doxorubicin insult.
Tang MY et al. Gene 2015 May 10;562(1):70-5
PMID:26098123 - Promoter nucleosome dynamics regulated by signalling through the CTD code.
Materne P et al. Elife 2015 Jun 22;4:e09008
PMID:28945192 - Regulated Ire1-dependent mRNA decay requires no-go mRNA degradation to maintain endoplasmic reticulum homeostasis in S. pombe .
Guydosh NR et al. Elife 2017 Sep 25;6
PMID:12724426 - Role for the fission yeast RecQ helicase in DNA repair in G2.
Laursen LV et al. Mol Cell Biol 2003 May;23(10):3692-705
PMID:15722486 - Biochemical characterization and DNA repair pathway interactions of Mag1-mediated base excision repair in Schizosaccharomyces pombe.
Alseth I et al. Nucleic Acids Res 2005;33(3):1123-31
PMID:22681890 - Hierarchical modularity and the evolution of genetic interactomes across species.
Ryan CJ et al. Mol Cell 2012 Jun 08;46(5):691-704
PMID:25414342 - Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination.
Lorenz A et al. Nucleic Acids Res 2014 Dec 16;42(22):13723-35
PMID:34250083 - Barcode sequencing and a high-throughput assay for chronological lifespan uncover ageing-associated genes in fission yeast.
Romila CA et al. Microb Cell 2021 Jul 05;8(7):146-160
PMID:26771498 - A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.
Vo TV et al. Cell 2016 Jan 14;164(1-2):310-323
PMID:12675805 - A new Schizosaccharomyces pombe base excision repair mutant, nth1, reveals overlapping pathways for repair of DNA base damage.
Osman F et al. Mol Microbiol 2003 Apr;48(2):465-80
PMID:11560889 - Multiple interactions among the components of the recombinational DNA repair system in Schizosaccharomyces pombe.
Tsutsui Y et al. Genetics 2001 Sep;159(1):91-105
PMID:15466419 - Swi5 acts in meiotic DNA joint molecule formation in Schizosaccharomyces pombe.
Ellermeier C et al. Genetics 2004 Dec;168(4):1891-8
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:16080597 - [The dds20+ gene controls a novel Rad51Sp-dependent pathway of recombinational repair in Schizosaccharomyces pombe].
Salakhova AF et al. Genetika 2005 Jun;41(6):736-45
PMID:24192486 - The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast.
Fontebasso Y et al. DNA Repair (Amst) 2013 Dec;12(12):1011-23
PMID:14668362 - Five RecA-like proteins of Schizosaccharomyces pombe are involved in meiotic recombination.
Grishchuk AL et al. Genetics 2003 Nov;165(3):1031-43
PMID:16135800 - The F-Box DNA helicase Fbh1 prevents Rhp51-dependent recombination without mediator proteins.
Osman F et al. Mol Cell Biol 2005 Sep;25(18):8084-96
PMID:24943839 - A role for nuclear envelope-bridging complexes in homology-directed repair.
Swartz RK et al. Mol Biol Cell 2014 Aug 15;25(16):2461-71
PMID:29550859 - Genetic interactions between the chromosome axis-associated protein Hop1 and homologous recombination determinants in Schizosaccharomyces pombe.
Brown SD et al. Curr Genet 2018 Oct;64(5):1089-1104
PMID:17353272 - Mus81-Eme1-dependent and -independent crossovers form in mitotic cells during double-strand break repair in Schizosaccharomyces pombe.
Hope JC et al. Mol Cell Biol 2007 May;27(10):3828-38
PMID:25373780 - A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.
Graml V et al. Dev Cell 2014 Oct 27;31(2):227-239
PMID:23628481 - A proteome-wide visual screen identifies fission yeast proteins localizing to DNA double-strand breaks.
Yu Y et al. DNA Repair (Amst) 2013 Jun 01;12(6):433-43
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:22737087 - The CCR4-NOT complex is implicated in the viability of aneuploid yeasts.
Tange Y et al. PLoS Genet 2012;8(6):e1002776
PMID:19547744 - Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.
Beltrao P et al. PLoS Biol 2009 Jun 16;7(6):e1000134
PMID:19798055 - Failed gene conversion leads to extensive end processing and chromosomal rearrangements in fission yeast.
Tinline-Purvis H et al. EMBO J 2009 Nov 04;28(21):3400-12
PMID:19037101 - Mus81, Rhp51(Rad51), and Rqh1 form an epistatic pathway required for the S-phase DNA damage checkpoint.
Willis N et al. Mol Biol Cell 2009 Feb;20(3):819-33
PMID:24875629 - Essential domains of Schizosaccharomyces pombe Rad8 required for DNA damage response.
Ding L et al. G3 (Bethesda) 2014 May 28;4(8):1373-84
PMID:17515930 - Rad3-dependent phosphorylation of the checkpoint clamp regulates repair-pathway choice.
Kai M et al. Nat Cell Biol 2007 Jun;9(6):691-7
PMID:16478984 - The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex.
Pebernard S et al. Mol Cell Biol 2006 Mar;26(5):1617-30
PMID:26791325 - Predicting chemotherapeutic drug combinations through gene network profiling.
Nguyen TT et al. Sci Rep 2016 Jan 21;6:18658
PMID:29898918 - Mutations that prevent methylation of cohesin render sensitivity to DNA damage in S. pombe .
Sanyal S et al. J Cell Sci 2018 Jul 06;131(13)
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12
PMID:25669599 - Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast.
Nguyen TT et al. Sci Rep 2015 Feb 11;5:8400
PMID:23365689 - Cellular robustness conferred by genetic crosstalk underlies resistance against chemotherapeutic drug doxorubicin in fission yeast.
Tay Z et al. PLoS One 2013;8(1):e55041
PMID:20885790 - Critical functions of Rpa3/Ssb3 in S-phase DNA damage responses in fission yeast.
Cavero S et al. PLoS Genet 2010 Sep 23;6(9):e1001138
PMID:10430583 - A new recombinational DNA repair gene from Schizosaccharomyces pombe with homology to Escherichia coli RecA.
Khasanov FK et al. Genetics 1999 Aug;152(4):1557-72
PMID:19264558 - Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.
Deshpande GP et al. DNA Repair (Amst) 2009 May 01;8(5):672-9
PMID:12023299 - Cdc2-cyclin B kinase activity links Crb2 and Rqh1-topoisomerase III.
Caspari T et al. Genes Dev 2002 May 15;16(10):1195-208
PMID:22907753 - Posttranscriptional regulation of cell-cell interaction protein-encoding transcripts by Zfs1p in Schizosaccharomyces pombe.
Wells ML et al. Mol Cell Biol 2012 Oct;32(20):4206-14
PMID:11726502 - Fission yeast Rad50 stimulates sister chromatid recombination and links cohesion with repair.
Hartsuiker E et al. EMBO J 2001 Dec 03;20(23):6660-71
PMID:27887640 - Functional and regulatory profiling of energy metabolism in fission yeast.
Malecki M et al. Genome Biol 2016 Nov 25;17(1):240
GO_REF:0000051 - S. pombe keyword mapping
PMID:17762865 - SUMO-targeted ubiquitin ligases in genome stability.
Prudden J et al. EMBO J 2007 Sep 19;26(18):4089-101
GO_REF:0000002 - Comments
PMID:22365419 - The Schizosaccharomyces pombe AlkB homolog Abh1 exhibits AP lyase activity but no demethylase activity.
Korvald H et al. DNA Repair (Amst) 2012 May 01;11(5):453-62
PMID:24013504 - Tpz1 controls a telomerase-nonextendible telomeric state and coordinates switching to an extendible state via Ccq1.
Jun HI et al. Genes Dev 2013 Sep 01;27(17):1917-31
PMID:33823663 - A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans.
Halova L et al. Open Biol 2021 Apr;11(4):200405
PMID:37330173 - Phosphoregulation of DNA repair via the Rad51 auxiliary factor Swi5-Sfr1.
Liang P et al. J Biol Chem 2023 Aug;299(8):104929
PANTHER:PTHR46239 - Unknown title
PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs
PMID:30824696 - Systematic analysis reveals the prevalence and principles of bypassable gene essentiality.
Li J et al. Nat Commun 2019 Mar 01;10(1):1002
PMID:15336631 - Identification and characterization of the rlp1+, the novel Rad51 paralog in the fission yeast Schizosaccharomyces pombe.
Khasanov FK et al. DNA Repair (Amst) 2004 Oct 05;3(10):1363-74
PMID:17178839 - Fission yeast Cut8 is required for the repair of DNA double-strand breaks, ribosomal DNA maintenance, and cell survival in the absence of Rqh1 helicase.
Kearsey SE et al. Mol Cell Biol 2007 Mar;27(5):1558-67
PMID:23695164 - Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.
Das J et al. Sci Signal 2013 May 21;6(276):ra38
PMID:18769921 - Genetic analysis reveals different roles of Schizosaccharomyces pombe sfr1/dds20 in meiotic and mitotic DNA recombination and repair.
Khasanov FK et al. Curr Genet 2008 Oct;54(4):197-211
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:12628934 - Pathway utilization in response to a site-specific DNA double-strand break in fission yeast.
Prudden J et al. EMBO J 2003 Mar 17;22(6):1419-30
PMID:17724078 - Break-induced loss of heterozygosity in fission yeast: dual roles for homologous recombination in promoting translocations and preventing de novo telomere addition.
Cullen JK et al. Mol Cell Biol 2007 Nov;27(21):7745-57
PMID:14993467 - The involvement of Srs2 in post-replication repair and homologous recombination in fission yeast.
Doe CL et al. Nucleic Acids Res 2004;32(4):1480-91
PMID:19205745 - Redundant roles of Srs2 helicase and replication checkpoint in survival and rDNA maintenance in Schizosaccharomyces pombe.
Yasuhira S Mol Genet Genomics 2009 May;281(5):497-509
PMID:37445861 - Resistance to Chemotherapeutic 5-Fluorouracil Conferred by Modulation of Heterochromatic Integrity through Ino80 Function in Fission Yeast.
Lim KK et al. Int J Mol Sci 2023 Jun 26;24(13)
PMID:35820914 - Antagonistic effects of mitochondrial matrix and intermembrane space proteases on yeast aging.
Vega M et al. BMC Biol 2022 Jul 12;20(1):160
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623