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protein coding gene - bet5 (SPAC3G9.16c) - TRAPP I, II and III complex RabGEF subunit Bet5

Gene summary

Standard name
bet5
Systematic ID
SPAC3G9.16c
Product
TRAPP I, II and III complex RabGEF subunit Bet5
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
SPAC688.15
UniProt ID
Q9UT70
ORFeome ID
05/05A10
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome I: 3145214..3145728 forward strand

Annotation

GO biological process

GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport

References:

GO:0006891 - intra-Golgi vesicle-mediated transport

References:

GO:0016236 - macroautophagy

References:

GO cellular component

GO:0005801 - cis-Golgi network

References:

GO:0005829 - cytosol

References:

GO:0005634 - nucleus

References:

GO:1990070 - TRAPPI protein complex

References:

GO:1990071 - TRAPPII protein complex

References:

GO:1990072 - TRAPPIII protein complex

References:

GO molecular function

GO:0005085 - guanyl-nucleotide exchange factor activity

References:

Qualitative gene expression

PomGeneEx:0000018 - protein level increased

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0001511 - inviable vegetative cell, abnormal cell shape, normal cell size

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

IDNameInterPro nameDB name
PF04099SybindinTRAPPCPfam
cd14855TRAPPC1_MUM2CDD
SM01399SybindinTRAPPCSMART
G3DSA:3.30.450.70CATH-Gene3D
SSF64356Longin-like_dom_sfSUPERFAMILY
PTHR23249TRAPPCPANTHER

Orthologs

References / Literature

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:20118936 - Schizosaccharomyces pombe genome-wide nucleosome mapping reveals positioning mechanisms distinct from those of Saccharomyces cerevisiae.
Lantermann AB et al. Nat Struct Mol Biol 2010 Feb;17(2):251-7
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.
Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105
GO_REF:0000051 - S. pombe keyword mapping