protein coding gene - sds22 (SPAC4A8.12c) - serine/threonine protein phosphatase PP1 regulatory subunit Sds22

Gene summary

Standard name

sds22

Systematic ID

SPAC4A8.12c

Product

serine/threonine protein phosphatase PP1 regulatory subunit Sds22

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

P22194

ORFeome ID

49/49A05

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome I: 2573160..2574541 reverse strand

Annotation

Protein features

Orthologs

• PPP1R7 (HGNC:9295) Homo sapiens
• sds22 (SJAG_04968) Schizosaccharomyces japonicus
• SDS22 (YKL193C) Saccharomyces cerevisiae

References / Literature

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7

PMID:15335873 - Mitotic regulation of protein phosphatases by the fission yeast sds22 protein.

Stone EM et al. Curr Biol 1993 Jan;3(1):13-26

PMID:1846086 - S. pombe gene sds22+ essential for a midmitotic transition encodes a leucine-rich repeat protein that positively modulates protein phosphatase-1.

Ohkura H et al. Cell 1991 Jan 11;64(1):149-57

PMID:26771498 - A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.

Vo TV et al. Cell 2016 Jan 14;164(1-2):310-323

PMID:22730331 - Dual recruitment of Cdc48 (p97)-Ufd1-Npl4 ubiquitin-selective segregase by small ubiquitin-like modifier protein (SUMO) and ubiquitin in SUMO-targeted ubiquitin ligase-mediated genome stability functions.

Nie M et al. J Biol Chem 2012 Aug 24;287(35):29610-9

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:8978689 - Requirement for PP1 phosphatase and 20S cyclosome/APC for the onset of anaphase is lessened by the dosage increase of a novel gene sds23+.

Ishii K et al. EMBO J 1996 Dec 02;15(23):6629-40

PMID:28821619 - Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast.

Burr R et al. J Biol Chem 2017 Sep 29;292(39):16333-16350

PMID:1944266 - The fission yeast dis3+ gene encodes a 110-kDa essential protein implicated in mitotic control.

Kinoshita N et al. Mol Cell Biol 1991 Dec;11(12):5839-47

PMID:16537923 - Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast.

Todd BL et al. Mol Cell Biol 2006 Apr;26(7):2817-31

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:24945319 - CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation.

Vanoosthuyse V et al. PLoS Genet 2014 Jun;10(6):e1004415

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

GO_REF:0000051 - S. pombe keyword mapping

PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36