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protein coding gene - sss1 (SPAC4G8.02c) - Sec61 translocon gamma subunit Sss1

Gene summary

Standard name
sss1
Systematic ID
SPAC4G8.02c
Product
Sec61 translocon gamma subunit Sss1
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
Q09827
ORFeome ID
04/04E12
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome I: 756479..757109 reverse strand

Annotation

GO biological process

GO:0031204 - post-translational protein targeting to membrane, translocation

References:

GO:0045048 - protein insertion into ER membrane

References:

GO:0006616 - SRP-dependent cotranslational protein targeting to membrane, translocation

References:

GO cellular component

GO:0005783 - endoplasmic reticulum

References:

GO:0005784 - Sec61 translocon complex

References:

GO:0071261 - Ssh1 translocon complex

References:

GO molecular function

GO:0008320 - transmembrane protein transporter activity

References:

Protein sequence feature

SO:0001812 - transmembrane_helix

References:

Qualitative gene expression

PomGeneEx:0000018 - protein level increased

References:

PomGeneEx:0000012 - RNA level decreased

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002151 - inviable spore

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

Taxonomic conservation

PBO:0011072 - conserved in archaea

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

IDNameInterPro nameDB name
PF00584SecETranslocase_SecE/Sec61-gPFAM
PS01067SECE_SEC61GTranslocase_SecE/Sec61-gPROSITE_PATTERNS
SSF103456Preprotein translocase SecE subunitProt_translocase_SecE_dom_sfSUPERFAMILY
G3DSA:1.20.5.820Preprotein translocase SecE subunitProt_translocase_SecE_dom_sfGENE3D
PTHR12309SEC61 GAMMA SUBUNITPANTHER
MF_00422SecETranslocase_SecE/Sec61-gHAMAP
TIGR00327secE_euk_archTranslocase_Sec61-gNCBIFAM

Orthologs

References / Literature

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:27984744 - Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs.
Joh RI et al. Mol Cell 2016 Dec 15;64(6):1088-1101
PMID:36478272 - Translation-complex profiling of fission yeast cells reveals dynamic rearrangements of scanning ribosomal subunits upon nutritional stress.
Duncan CDS et al. Nucleic Acids Res 2022 Dec 09;50(22):13011-13025
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.
Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105
GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:11152613 - Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes.
Krogh A et al. J Mol Biol 2001 Jan 19;305(3):567-80
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36