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protein coding gene - pex22 (SPAC57A7.15c) - peroxisomal membrane E2 ubiquitin-conjugating activity activator Pex22

Gene summary

Standard name
pex22
Systematic ID
SPAC57A7.15c
Product
peroxisomal membrane E2 ubiquitin-conjugating activity activator Pex22
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
C6Y4B2
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome I: 1545323..1546092 reverse strand

Annotation

GO biological process

GO:0016562 - protein import into peroxisome matrix, receptor recycling

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GO cellular component

GO:0005778 - peroxisomal membrane

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GO molecular function

GO:0097027 - ubiquitin-protein transferase activator activity

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Quantitative gene expression

PBO:0011963 - RNA level

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Single locus phenotype

FYPO:0000151 - abnormal meiotic chromosome segregation

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Genotypes:

FYPO:0009091 - decreased cell population growth on lysine and proline nitrogen source

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Genotypes:

FYPO:0009072 - increased cell population growth on lysine nitrogen source

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Genotypes:

FYPO:0002693 - resistance to diamide

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Genotypes:

FYPO:0009038 - resistance to egtazic acid

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Genotypes:

FYPO:0007808 - resistance to valproic acid

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Genotypes:

FYPO:0000830 - resistance to vanadate

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Genotypes:

FYPO:0000096 - sensitive to cadmium

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Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

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PBO:0011071 - conserved in eukaryotes only

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PBO:0011064 - conserved in fungi

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PBO:0006222 - predominantly single copy (one to one)

Warnings

PBO:0000082 - new gene

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Orthologs

References / Literature

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PB_REF:0000008 - Distant orthologs supported by Pfam-N
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PB_REF:0000008,PMID:37156916 - Unknown title
PMID:18488015 - Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution.
Wilhelm BT et al. Nature 2008 Jun 26;453(7199):1239-43
PMID:29259000 - Genes Important for Schizosaccharomyces pombe Meiosis Identified Through a Functional Genomics Screen.
Blyth J et al. Genetics 2018 Feb;208(2):589-603
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12