PomBase - protein coding gene - rpn9 (SPAC607.05) - 19S proteasome regulatory subunit Rpn9 - The Schizosaccharomyces pombe genome database

ID	Name	InterPro name	DB name
PF01399	PCI	PCI_dom	Pfam
PF18261	Rpn9_C	Rpn9_C	Pfam
PF22037	PSD13_N	PSD13_N	Pfam
PS50250	PCI	PCI_dom	PROSITE profiles
SM00088	PINT	PCI_dom	SMART
SSF46785		WH_DNA-bd_sf	SUPERFAMILY
PTHR10539		PSMD13	PANTHER
Coil			COILS

References / Literature

PMID:20838651 - A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity.: Kouranti I et al. PLoS Biol 2010 Sep 07;8(9)
PMID:21098295 - Structure of the 26S proteasome from Schizosaccharomyces pombe at subnanometer resolution.: Bohn S et al. Proc Natl Acad Sci U S A 2010 Dec 07;107(49):20992-7
PMID:39473973 - Limiting 20S proteasome assembly leads to unbalanced nucleo-cytoplasmic distribution of 26S/30S proteasomes and chronic proteotoxicity.: Ruiz-Romero G et al. iScience 2024 Nov 15;27(11):111095
PMID:16537923 - Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast.: Todd BL et al. Mol Cell Biol 2006 Apr;26(7):2817-31
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.: Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).: Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:28784663 - The 19S proteasome is directly involved in the regulation of heterochromatin spreading in fission yeast.: Seo HD et al. J Biol Chem 2017 Oct 13;292(41):17144-17155
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.: Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.: Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:17761670 - Isolation of the Schizosaccharomyces pombe proteasome subunit Rpn7 and a structure-function study of the proteasome-COP9-initiation factor domain.: Sha Z et al. J Biol Chem 2007 Nov 02;282(44):32414-23
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:24938783 - Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes.: Leitner A et al. Proc Natl Acad Sci U S A 2014 Jul 01;111(26):9455-60
PMID:28218250 - Chromatin remodeller Fun30 Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.: Lee J et al. Nat Commun 2017 Feb 20;8:14527
PMID:22119525 - SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast.: Singh NS et al. Curr Biol 2011 Dec 06;21(23):1968-78
PMID:23163955 - Analysis of stress-induced duplex destabilization (SIDD) properties of replication origins, genes and intergenes in the fission yeast, Schizosaccharomyces pombe.: Yadav MP et al. BMC Res Notes 2012 Nov 19;5:643
PMID:30355493 - Expanded Interactome of the Intrinsically Disordered Protein Dss1.: Schenstrøm SM et al. Cell Rep 2018 Oct 23;25(4):862-870
PMID:34496258 - Transcription and chromatin-based surveillance mechanism controls suppression of cryptic antisense transcription.: Heo DH et al. Cell Rep 2021 Sep 07;36(10):109671
PMID:38285941 - Specialized replication of heterochromatin domains ensures self-templated chromatin assembly and epigenetic inheritance.: Nathanailidou P et al. Proc Natl Acad Sci U S A 2024 Feb 06;121(6):e2315596121
PMID:26412298 - A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.: Beckley JR et al. Mol Cell Proteomics 2015 Dec;14(12):3132-41
GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference
PMID:23209828 - Fission yeast 26S proteasome mutants are multi-drug resistant due to stabilization of the Pap1 transcription factor.: Penney M et al. PLoS One 2012;7(11):e50796
PMID:20133687 - Synergistic roles of the proteasome and autophagy for mitochondrial maintenance and chronological lifespan in fission yeast.: Takeda K et al. Proc Natl Acad Sci U S A 2010 Feb 23;107(8):3540-5
PMID:21511999 - Comparative functional genomics of the fission yeasts.: Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:12783882 - Rpn5 is a conserved proteasome subunit and required for proper proteasome localization and assembly.: Yen HC et al. J Biol Chem 2003 Aug 15;278(33):30669-76

protein coding gene - rpn9 (SPAC607.05) - 19S proteasome regulatory subunit Rpn9

Gene summary

Annotation

GO biological process

GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process

GO cellular component

GO:0005829 - cytosol

GO:0005634 - nucleus

GO:0008541 - proteasome regulatory particle, lid subcomplex

GO molecular function

GO:0005198 - structural molecule activity

Qualitative gene expression

PomGeneEx:0000012 - RNA level decreased

Quantitative gene expression

PBO:0006310 - protein level

PBO:0011963 - RNA level

Single locus phenotype

FYPO:0002187 - inviable normal volume spheroid vegetative cell

FYPO:0002061 - inviable vegetative cell population

FYPO:0001387 - loss of viability at high temperature

FYPO:0000067 - resistance to brefeldin A

FYPO:0000073 - resistance to caffeine

FYPO:0004025 - resistance to carbendazim

FYPO:0000767 - resistance to staurosporine

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

Orthologs

References / Literature