protein coding gene - moe1 (SPAC637.07) - translation initiation factor eIF3d
Gene summary
- Standard name
- moe1
- Systematic ID
- SPAC637.07
- Product
- translation initiation factor eIF3d
- Organism
- Schizosaccharomyces pombe
(fission yeast)
- Synonyms
- tif304
- UniProt ID
- O94236
- ORFeome ID
- 35/35D10
- Characterisation status
- biological role published
- Feature type
- mRNA gene
- Genomic location
- chromosome I: 4551840..4553741 forward strand
Annotation
Qualitative gene expression
Quantitative gene expression
Protein features
| ID | Name | InterPro name | DB name |
| PF05091 | eIF-3_zeta | eIF3d | Pfam |
| PTHR12399 | | eIF3d | PANTHER |
| PIRSF016281 | EIF-3_zeta | eIF3d | PIRSF |
| MF_03003 | eIF3d | eIF3d | HAMAP |
| mobidb-lite-Disorder | disorder_prediction | | MobiDB-Disorder |
| mobidb-lite-Glycine-rich | disorder_prediction | | MobiDB-Glycine-rich |
Orthologs
- EIF3D (HGNC:3278) Homo sapiens
- moe1 (SJAG_02995) Schizosaccharomyces japonicus
References / Literature
- PMID:39367033 - Quantitative proteomics and phosphoproteomics profiling of meiotic divisions in the fission yeast Schizosaccharomyces pombe.
- Sivakova B et al. Sci Rep 2024 Oct 04;14(1):23105
- PMID:27481777 - Identification of nuclear genes affecting 2-Deoxyglucose resistance in Schizosaccharomyces pombe.
- Vishwanatha A et al. FEMS Yeast Res 2016 Sep;16(6)
- PMID:24634168 - Proteome-wide search for PP2A substrates in fission yeast.
- Bernal M et al. Proteomics 2014 Jun;14(11):1367-80
- PMID:19672306 - Genome-wide screen of genes required for caffeine tolerance in fission yeast.
- Calvo IA et al. PLoS One 2009 Aug 12;4(8):e6619
- PMID:11705997 - Moe1 and spInt6, the fission yeast homologues of mammalian translation initiation factor 3 subunits p66 (eIF3d) and p48 (eIF3e), respectively, are required for stable association of eIF3 subunits.
- Bandyopadhyay A et al. J Biol Chem 2002 Jan 18;277(3):2360-7
- PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
- Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
- PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
- Rodríguez-López M et al. Elife 2023 Oct 03;12
- PMID:16278451 - Activation of AP-1-dependent transcription by a truncated translation initiation factor.
- Jenkins CC et al. Eukaryot Cell 2005 Nov;4(11):1840-50
- PMID:33419777 - Identification of mutants with increased variation in cell size at onset of mitosis in fission yeast.
- Scotchman E et al. J Cell Sci 2021 Feb 11;134(3)
- PMID:19336419 - Cotranscriptional recruitment of the nuclear poly(A)-binding protein Pab2 to nascent transcripts and association with translating mRNPs.
- Lemieux C et al. Nucleic Acids Res 2009 Jun;37(10):3418-30
- PMID:22681890 - Hierarchical modularity and the evolution of genetic interactomes across species.
- Ryan CJ et al. Mol Cell 2012 Jun 08;46(5):691-704
- PMID:25720772 - Quantitative phosphoproteomics reveals pathways for coordination of cell growth and division by the conserved fission yeast kinase pom1.
- Kettenbach AN et al. Mol Cell Proteomics 2015 May;14(5):1275-87
- PMID:39705284 - Proteomic and phosphoproteomic analyses reveal that TORC1 is reactivated by pheromone signaling during sexual reproduction in fission yeast.
- Bérard M et al. PLoS Biol 2024 Dec 20;22(12):e3002963
- PMID:9892665 - Moe1, a conserved protein in Schizosaccharomyces pombe, interacts with a Ras effector, Scd1, to affect proper spindle formation.
- Chen CR et al. Proc Natl Acad Sci U S A 1999 Jan 19;96(2):517-22
- PMID:34250083 - Barcode sequencing and a high-throughput assay for chronological lifespan uncover ageing-associated genes in fission yeast.
- Romila CA et al. Microb Cell 2021 Jul 05;8(7):146-160
- PMID:25483073 - Chromosome segregation and organization are targets of 5'-Fluorouracil in eukaryotic cells.
- Mojardín L et al. Cell Cycle 2015;14(2):206-18
- PMID:20016281 - Int6 and Moe1 interact with Cdc48 to regulate ERAD and proper chromosome segregation.
- Otero JH et al. Cell Cycle 2010 Jan 01;9(1):147-61
- PMID:11121040 - Yin6, a fission yeast Int6 homolog, complexes with Moe1 and plays a role in chromosome segregation.
- Yen HC et al. Proc Natl Acad Sci U S A 2000 Dec 19;97(26):14370-5
- PMID:24957674 - Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts.
- Anver S et al. EMBO Rep 2014 Aug;15(8):894-902
- PMID:27887640 - Functional and regulatory profiling of energy metabolism in fission yeast.
- Malecki M et al. Genome Biol 2016 Nov 25;17(1):240
- PMID:30355493 - Expanded Interactome of the Intrinsically Disordered Protein Dss1.
- Schenstrøm SM et al. Cell Rep 2018 Oct 23;25(4):862-870
- PMID:36478272 - Translation-complex profiling of fission yeast cells reveals dynamic rearrangements of scanning ribosomal subunits upon nutritional stress.
- Duncan CDS et al. Nucleic Acids Res 2022 Dec 09;50(22):13011-13025
- PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
- Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
- PMID:12052869 - Two ras pathways in fission yeast are differentially regulated by two ras guanine nucleotide exchange factors.
- Papadaki P et al. Mol Cell Biol 2002 Jul;22(13):4598-606
- PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
- Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
- PMID:25651869 - Chemical genomics approach to identify genes associated with sensitivity to rapamycin in the fission yeast Schizosaccharomyces pombe.
- Doi A et al. Genes Cells 2015 Apr;20(4):292-309
- PMID:27918601 - Identifying genes required for respiratory growth of fission yeast.
- Malecki M et al. Wellcome Open Res 2016;1:12
- GO_REF:0000033 - Annotation inferences using phylogenetic trees
-
- PMID:28410370 - A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.
- Dudin O et al. PLoS Genet 2017 Apr;13(4):e1006721
- PMID:11102508 - A conserved interaction between Moe1 and Mal3 is important for proper spindle formation in Schizosaccharomyces pombe.
- Chen CR et al. Mol Biol Cell 2000 Dec;11(12):4067-77
- PMID:26771498 - A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.
- Vo TV et al. Cell 2016 Jan 14;164(1-2):310-323
- GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
-
- PMID:34984977 - Functional profiling of long intergenic non-coding RNAs in fission yeast.
- Rodriguez-Lopez M et al. Elife 2022 Jan 05;11
- PMID:33313903 - Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast.
- Rubio A et al. Nucleic Acids Res 2021 Jan 11;49(1):383-399
- PMID:21511999 - Comparative functional genomics of the fission yeasts.
- Rhind N et al. Science 2011 May 20;332(6032):930-6
- PMID:28821619 - Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast.
- Burr R et al. J Biol Chem 2017 Sep 29;292(39):16333-16350
- PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
- Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
- PMID:28218250 - Chromatin remodeller Fun30 Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.
- Lee J et al. Nat Commun 2017 Feb 20;8:14527
- PMID:12553909 - Schizosaccharomyces pombe Int6 and Ras homologs regulate cell division and mitotic fidelity via the proteasome.
- Yen HC et al. Cell 2003 Jan 24;112(2):207-17
- PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
- Hayles J et al. Open Biol 2013 May 22;3(5):130053
- PMID:23950735 - Global analysis of fission yeast mating genes reveals new autophagy factors.
- Sun LL et al. PLoS Genet 2013;9(8):e1003715
- PMID:27984744 - Survival in Quiescence Requires the Euchromatic Deployment of Clr4/SUV39H by Argonaute-Associated Small RNAs.
- Joh RI et al. Mol Cell 2016 Dec 15;64(6):1088-1101
- PMID:33823663 - A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans.
- Halova L et al. Open Biol 2021 Apr;11(4):200405
- PMID:37970674 - SUMOylation regulates Lem2 function in centromere clustering and silencing.
- Strachan J et al. J Cell Sci 2023 Dec 01;136(23)
- PMID:19061185 - Fission yeast translation initiation factor 3 subunit eIF3h is not essential for global translation initiation, but deletion of eif3h+ affects spore formation.
- Ray A et al. Yeast 2008 Nov;25(11):809-23
- PMID:30726745 - Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex.
- Tay YD et al. Cell Rep 2019 Feb 05;26(6):1654-1667.e7
- PMID:32071154 - Fission Yeast Puf2, a Pumilio and FBF Family RNA-Binding Protein, Links Stress Granules to Processing Bodies.
- Hsiao WY et al. Mol Cell Biol 2020 Apr 13;40(9)
- PMID:15904532 - PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes.
- Zhou C et al. BMC Biol 2005 May 17;3:14
