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protein coding gene - mrpl9 (SPAC644.17c) - mitochondrial ribosomal protein subunit L3

Gene summary

Standard name
mrpl9
Systematic ID
SPAC644.17c
Product
mitochondrial ribosomal protein subunit L3
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
mrp9
UniProt ID
Q9P6P6
ORFeome ID
09/09G03
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome I: 2701420..2703811 reverse strand

Annotation

Disease association

MONDO:0013811 - combined oxidative phosphorylation defect type 9

References:

GO biological process

GO:0032543 - mitochondrial translation

References:

GO cellular component

GO:0005737 - cytoplasm

References:

GO:0005762 - mitochondrial large ribosomal subunit

References:

GO molecular function

GO:0003735 - structural constituent of ribosome

References:

Protein sequence feature

SO:0001808 - mitochondrial_targeting_signal

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002111 - inviable tapered vegetative cell

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

FYPO:0002199 - inviable vegetative cell with normal cell morphology

References:

Genotypes:

Taxonomic conservation

PBO:0011067 - conserved in bacteria

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

IDNameInterPro nameDB name
PF00297Ribosomal_L3Ribosomal_uL3PFAM
PS00474RIBOSOMAL_L3Ribosomal_uL3_CSPROSITE_PATTERNS
G3DSA:2.40.30.10:FF:000004FUNFAM
G3DSA:3.30.160.810:FF:000001FUNFAM
SSF50447Translation proteinsTransl_B-barrel_sfSUPERFAMILY
G3DSA:2.40.30.10Translation factorsGENE3D
G3DSA:3.30.160.810GENE3D
PTHR1122950S RIBOSOMAL PROTEIN L3Ribosomal_uL3_bact_orgPANTHER
MF_01325_BRibosomal_uL3_BRibosomal_uL3_bact_orgHAMAP
mobidb-lite-Disorderdisorder_predictionMOBIDB-Disorder
mobidb-lite-Polardisorder_predictionMOBIDB-Polar
TIGR03625L3_bactRibosomal_uL3_bact_orgNCBIFAM

Orthologs

References / Literature

PMID:26771498 - A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.
Vo TV et al. Cell 2016 Jan 14;164(1-2):310-323
PMID:30321377 - Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome.
Telekawa C et al. Nucleic Acids Res 2018 Nov 30;46(21):11169-11183
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
GO_REF:0000033 - Annotation inferences using phylogenetic trees
PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:36408920 - UniProt: the Universal Protein Knowledgebase in 2023.
UniProt Consortium Nucleic Acids Res 2023 Jan 06;51(D1):D523-D531
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:23297348 - Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase.
Chen JS et al. Mol Cell Proteomics 2013 May;12(5):1074-86
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36