protein coding gene - bqt1 (SPAC6G9.13c) - bouquet formation protein Bqt1

Gene summary

Standard name

bqt1

Systematic ID

SPAC6G9.13c

Product

bouquet formation protein Bqt1

Organism

Schizosaccharomyces pombe (fission yeast)

Synonyms

mug23, rec26

UniProt ID

Q92358

ORFeome ID

01/01E06

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome I: 3272076..3272699 reverse strand

Annotation

Orthologs

• bqt1 (SJAG_05260) Schizosaccharomyces japonicus

References / Literature

PMID:12161753 - The transcriptional program of meiosis and sporulation in fission yeast.

Mata J et al. Nat Genet 2002 Sep;32(1):143-7

PMID:22681890 - Hierarchical modularity and the evolution of genetic interactomes across species.

Ryan CJ et al. Mol Cell 2012 Jun 08;46(5):691-704

PMID:26670050 - Regulation of mRNA Levels by Decay-Promoting Introns that Recruit the Exosome Specificity Factor Mmi1.

Kilchert C et al. Cell Rep 2015 Dec 22;13(11):2504-2515

PMID:27889481 - Mitotic Nuclear Envelope Breakdown and Spindle Nucleation Are Controlled by Interphase Contacts between Centromeres and the Nuclear Envelope.

Fernández-Álvarez A et al. Dev Cell 2016 Dec 05;39(5):544-559

PMID:20625380 - A genome-wide screen for Schizosaccharomyces pombe deletion mutants that affect telomere length.

Liu NN et al. Cell Res 2010 Aug;20(8):963-5

PMID:34067465 - The Meiosis-Specific Crs1 Cyclin Is Required for Efficient S-Phase Progression and Stable Nuclear Architecture.

Bustamante-Jaramillo LF et al. Int J Mol Sci 2021 May 22;22(11)

PMID:28974540 - The fission yeast nucleoporin Alm1 is required for proteasomal degradation of kinetochore components.

Salas-Pino S et al. J Cell Biol 2017 Nov 06;216(11):3591-3608

PMID:17632059 - The telomere bouquet controls the meiotic spindle.

Tomita K et al. Cell 2007 Jul 13;130(1):113-26

PMID:25375137 - Systematic analysis of the role of RNA-binding proteins in the regulation of RNA stability.

Hasan A et al. PLoS Genet 2014 Nov;10(11):e1004684

PMID:25452419 - Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Sideri T et al. G3 (Bethesda) 2014 Dec 01;5(1):145-55

PMID:29123917 - The telomere bouquet facilitates meiotic prophase progression and exit in fission yeast.

Moiseeva V et al. Cell Discov 2017;3:17041

PMID:34346498 - Loss of kinesin-8 improves the robustness of the self-assembled spindle in Schizosaccharomyces pombe.

Pineda-Santaella A et al. J Cell Sci 2021 Aug 15;134(16)

PMID:16615890 - Meiotic proteins bqt1 and bqt2 tether telomeres to form the bouquet arrangement of chromosomes.

Chikashige Y et al. Cell 2006 Apr 07;125(1):59-69

PMID:22582262 - Meiosis-specific noncoding RNA mediates robust pairing of homologous chromosomes in meiosis.

Ding DQ et al. Science 2012 May 11;336(6082):732-6

PMID:16823445 - Selective elimination of messenger RNA prevents an incidence of untimely meiosis.

Harigaya Y et al. Nature 2006 Jul 06;442(7098):45-50

PMID:16303567 - A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Martín-Castellanos C et al. Curr Biol 2005 Nov 22;15(22):2056-62

PMID:34250083 - Barcode sequencing and a high-throughput assay for chronological lifespan uncover ageing-associated genes in fission yeast.

Romila CA et al. Microb Cell 2021 Jul 05;8(7):146-160

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7

PMID:27611693 - A Taz1- and Microtubule-Dependent Regulatory Relationship between Telomere and Centromere Positions in Bouquet Formation Secures Proper Meiotic Divisions.

Katsumata K et al. PLoS Genet 2016 Sep;12(9):e1006304

PMID:23337086 - Purification and characterization of the fission yeast telomere clustering factors, Bqt1 and Bqt2.

Ichikawa Y et al. Protein Expr Purif 2013 Apr;88(2):207-13

PMID:23133674 - Identification of the functional domains of the telomere protein Rap1 in Schizosaccharomyces pombe.

Fujita I et al. PLoS One 2012;7(11):e49151

PMID:26058898 - Telomere protein Rap1 is a charge resistant scaffolding protein in chromosomal bouquet formation.

Amelina H et al. BMC Biol 2015 Jun 10;13:37

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:33260998 - High-Throughput Flow Cytometry Combined with Genetic Analysis Brings New Insights into the Understanding of Chromatin Regulation of Cellular Quiescence.

Zahedi Y et al. Int J Mol Sci 2020 Nov 27;21(23)

PMID:28410370 - A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Dudin O et al. PLoS Genet 2017 Apr;13(4):e1006721

PMID:31131414 - Casein kinase 2 regulates telomere protein complex formation through Rap1 phosphorylation.

Inoue H et al. Nucleic Acids Res 2019 Jul 26;47(13):6871-6884

PMID:20364342 - Functional interactions among members of the meiotic initiation complex in fission yeast.

Steiner S et al. Curr Genet 2010 Jun;56(3):237-49

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.

Rodríguez-López M et al. Elife 2023 Oct 03;12

PMID:21981922 - A Pre-mRNA degradation pathway that selectively targets intron-containing genes requires the nuclear poly(A)-binding protein.

Lemieux C et al. Mol Cell 2011 Oct 07;44(1):108-19

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:22959349 - Telomere-nuclear envelope dissociation promoted by Rap1 phosphorylation ensures faithful chromosome segregation.

Fujita I et al. Curr Biol 2012 Oct 23;22(20):1932-7

PMID:25688135 - Telomeres and centromeres have interchangeable roles in promoting meiotic spindle formation.

Fennell A et al. J Cell Biol 2015 Feb 16;208(4):415-28

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053