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protein coding gene - ost4 (SPAC7D4.15c) - oligosaccharyltransferase complex subunit, Ost4

Gene summary

Standard name
ost4
Systematic ID
SPAC7D4.15c
Product
oligosaccharyltransferase complex subunit, Ost4
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
Q96VG2
ORFeome ID
51/51F05
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome I: 2623940..2624084 reverse strand

Annotation

GO biological process

GO:0006487 - protein N-linked glycosylation

References:

GO cellular component

GO:0032541 - cortical endoplasmic reticulum

References:

GO:0005783 - endoplasmic reticulum

References:

GO:0008250 - oligosaccharyltransferase complex

References:

GO:0097038 - perinuclear endoplasmic reticulum

References:

Protein sequence feature

SO:0001812 - transmembrane_helix

References:

Quantitative gene expression

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0000310 - inviable after spore germination, without cell division, with normal germ tube morphology

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Genotypes:

FYPO:0002482 - inviable spheroid vegetative cell

References:

Genotypes:

FYPO:0002151 - inviable spore

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

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Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

IDNameInterPro nameDB name
PF10215Ost4OligosaccaryltransferasePfam
SSF103464Ost4p_sfSUPERFAMILY
Transmembrane alpha helixDeepTMHMM

Orthologs

References / Literature

GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:33109728 - High-Throughput Identification of Nuclear Envelope Protein Interactions in Schizosaccharomyces pombe Using an Arrayed Membrane Yeast-Two Hybrid Library.
Varberg JM et al. G3 (Bethesda) 2020 Dec 03;10(12):4649-4663
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:11152613 - Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes.
Krogh A et al. J Mol Biol 2001 Jan 19;305(3):567-80
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
PMID:27737912 - Atg20- and Atg24-family proteins promote organelle autophagy in fission yeast.
Zhao D et al. J Cell Sci 2016 Nov 15;129(22):4289-4304
PMID:37939137 - The ortholog of human REEP1-4 is required for autophagosomal enclosure of ER-phagy/nucleophagy cargos in fission yeast.
Zou CX et al. PLoS Biol 2023 Nov;21(11):e3002372
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83