protein coding gene - cdc24 (SPAC8F11.07c) - DNA replication protein Cdc24

Gene summary

Standard name

cdc24

Systematic ID

SPAC8F11.07c

Product

DNA replication protein Cdc24

Organism

Schizosaccharomyces pombe (fission yeast)

UniProt ID

O75004

ORFeome ID

33/33E03

Characterisation status

biological role published

Feature type

mRNA gene

Genomic location

chromosome I: 2863730..2865826 reverse strand

Annotation

Protein features

Orthologs

• cdc24 (SJAG_05232) Schizosaccharomyces japonicus

References / Literature

PMID:9891039 - Fission yeast cdc24 is a replication factor C- and proliferating cell nuclear antigen-interacting factor essential for S-phase completion.

Tanaka H et al. Mol Cell Biol 1999 Feb;19(2):1038-48

Pfam:PF17244 - Unknown title

PMID:9649516 - Fission yeast cdc24(+) encodes a novel replication factor required for chromosome integrity.

Gould KL et al. Genetics 1998 Jul;149(3):1221-33

PMID:10628977 - Isolation and characterization of Nrf1p, a novel negative regulator of the Cdc42p GTPase in Schizosaccharomyces pombe.

Murray JM et al. Genetics 2000 Jan;154(1):155-65

PMID:11027263 - Schizosaccharomyces pombe Hsk1p is a potential cds1p target required for genome integrity.

Snaith HA et al. Mol Cell Biol 2000 Nov;20(21):7922-32

PMID:15302919 - Genetic and biochemical analyses of Pfh1 DNA helicase function in fission yeast.

Ryu GH et al. Nucleic Acids Res 2004;32(14):4205-16

PMID:12455694 - mcl1+, the Schizosaccharomyces pombe homologue of CTF4, is important for chromosome replication, cohesion, and segregation.

Williams DR et al. Eukaryot Cell 2002 Oct;1(5):758-73

PMID:15576681 - Genetics of lagging strand DNA synthesis and maturation in fission yeast: suppression analysis links the Dna2-Cdc24 complex to DNA polymerase delta.

Tanaka H et al. Nucleic Acids Res 2004;32(21):6367-77

PMID:1934126 - Common genes and pathways in the regulation of the mitotic and meiotic cell cycles of Schizosaccharomyces pombe.

Grallert B et al. Curr Genet 1991 Aug;20(3):199-204

PMID:9928931 - The S/M checkpoint at 37 degrees C and the recovery of viability of the mutant poldeltats3 require the crb2+/rhp9+ gene in fission yeast.

Grenon M et al. Mol Gen Genet 1999 Jan;260(6):522-34

PMID:25203555 - Fission yeast Pxd1 promotes proper DNA repair by activating Rad16XPF and inhibiting Dna2.

Zhang JM et al. PLoS Biol 2014 Sep;12(9):e1001946

PMID:10880469 - Genetic analyses of Schizosaccharomyces pombe dna2(+) reveal that dna2 plays an essential role in Okazaki fragment metabolism.

Kang HY et al. Genetics 2000 Jul;155(3):1055-67

PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.

Marguerat S et al. Cell 2012 Oct 26;151(3):671-83

PMID:9135148 - p56(chk1) protein kinase is required for the DNA replication checkpoint at 37 degrees C in fission yeast.

Francesconi S et al. EMBO J 1997 Mar 17;16(6):1332-41

PMID:10888871 - Mitotic replication initiation proteins are not required for pre-meiotic S phase.

Forsburg SL et al. Nat Genet 2000 Jul;25(3):263-8

PMID:10388806 - Rereplication phenomenon in fission yeast requires MCM proteins and other S phase genes.

Snaith HA et al. Genetics 1999 Jul;152(3):839-51

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.

Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623

PMID:21511999 - Comparative functional genomics of the fission yeasts.

Rhind N et al. Science 2011 May 20;332(6032):930-6

PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.

Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7

PMID:12409464 - The fission yeast pfh1(+) gene encodes an essential 5' to 3' DNA helicase required for the completion of S-phase.

Tanaka H et al. Nucleic Acids Res 2002 Nov 01;30(21):4728-39

PMID:6943408 - Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe.

Nasmyth K et al. Mol Gen Genet 1981;182(1):119-24

PMID:18667534 - Activation of the DNA damage checkpoint in mutants defective in DNA replication initiation.

Yin L et al. Mol Biol Cell 2008 Oct;19(10):4374-82

PMID:23628481 - A proteome-wide visual screen identifies fission yeast proteins localizing to DNA double-strand breaks.

Yu Y et al. DNA Repair (Amst) 2013 Jun 01;12(6):433-43

PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.

Hayles J et al. Open Biol 2013 May 22;3(5):130053

PMID:9799358 - Cdm1, the smallest subunit of DNA polymerase d in the fission yeast Schizosaccharomyces pombe, is non-essential for growth and division.

Reynolds N et al. Curr Genet 1998 Oct;34(4):250-8

PMID:27729451 - Cdc24 Is Essential for Long-range End Resection in the Repair of Double-stranded DNA Breaks.

Zhang H et al. J Biol Chem 2016 Nov 25;291(48):24961-24973

PMID:9154809 - A novel mutant allele of Schizosaccharomyces pombe rad26 defective in monitoring S-phase progression to prevent premature mitosis.

Uchiyama M et al. Mol Cell Biol 1997 Jun;17(6):3103-15