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protein coding gene - ina22 (SPAC926.10) - mitochondrial F1-FO ATP synthase peripheral stalk assembly factor Ina22

Gene summary

Standard name
ina22
Systematic ID
SPAC926.10
Product
mitochondrial F1-FO ATP synthase peripheral stalk assembly factor Ina22
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
new9
UniProt ID
G2TRN2
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome I: 3886097..3886270 reverse strand

Annotation

Comment

PBO:0114110 - much shorter than S. c Ina22, butpicked up by Jackhmmr with good score/motif conservation

GO biological process

GO:0033615 - mitochondrial proton-transporting ATP synthase complex assembly

References:

GO cellular component

GO:1990524 - INA complex

References:

Protein sequence feature

SO:0000418 - signal_peptide

References:

SO:0001812 - transmembrane_helix

References:

Quantitative gene expression

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0009038 - resistance to egtazic acid

References:

Genotypes:

FYPO:0002767 - resistance to terbinafine

References:

Genotypes:

FYPO:0003383 - resistance to tert-butyl hydroperoxide

References:

Genotypes:

FYPO:0001501 - sensitive to brefeldin A

References:

Genotypes:

FYPO:0009088 - sensitive to magnesium chloride and sodium dodecyl sulfate

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011063 - conserved in fungi only

PBO:0006222 - predominantly single copy (one to one)

Warnings

PBO:0000082 - new gene

References:

Protein features

IDNameInterPro nameDB name
Transmembrane alpha helixDeepTMHMM
Signal PeptideDeepTMHMM-Signal-Peptide
CoilCOILS

Orthologs

References / Literature

PMID:21270388 - Augmented annotation of the Schizosaccharomyces pombe genome reveals additional genes required for growth and viability.
Bitton DA et al. Genetics 2011 Apr;187(4):1207-17
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:34980915 - SignalP 6.0 predicts all five types of signal peptides using protein language models.
Teufel F et al. Nat Biotechnol 2022 Jul;40(7):1023-1025
PMID:11152613 - Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes.
Krogh A et al. J Mol Biol 2001 Jan 19;305(3):567-80