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protein coding gene - pfl6 (SPAC977.07c) - cell surface glycoprotein, flocculin Pfl6

Gene summary

Standard name
pfl6
Systematic ID
SPAC977.07c
Product
cell surface glycoprotein, flocculin Pfl6
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
P0CU05
Characterisation status
biological role published
Feature type
mRNA gene
Genomic location
chromosome I: 42057..43307 reverse strand

Annotation

GO biological process

GO:0000128 - flocculation

References:

GO cellular component

GO:0010339 - external side of cell wall

References:

GO molecular function

GO:0098632 - cell-cell adhesion mediator activity

References:

Genome organisation

PBO:0000066 - telomeric duplication

Miscellaneous functional group

PBO:0000068 - cell surface glycoprotein

Modification

MOD:00693 - glycosylated residue

References:

MOD:00006 - N-glycosylated residue

References:

Protein features

PBO:0111742 - GLEYA domain

References:

Protein sequence feature

SO:0000418 - signal_peptide

References:

Quantitative gene expression

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0000155 - increased flocculation

References:

Genotypes:

FYPO:0009038 - resistance to egtazic acid

References:

Genotypes:

FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0000725 - resistance to methyl methanesulfonate

References:

Genotypes:

FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

References:

Genotypes:

FYPO:0001719 - sensitive to lithium

References:

Genotypes:

FYPO:0002060 - viable vegetative cell population

References:

Genotypes:

Taxonomic conservation

PBO:0011064 - conserved in fungi

PBO:0011063 - conserved in fungi only

PBO:0000055 - no apparent S. cerevisiae ortholog

Protein features

IDNameInterPro nameDB name
PF10528GLEYAGLEYA_adhesin_domainPFAM
PS51820PA14PA14/GLEYAPROSITE_PROFILES
G3DSA:2.60.120.1560:FF:000006FUNFAM
G3DSA:2.60.120.1560GENE3D
PTHR31492M CELL-TYPE AGGLUTINATION PROTEIN MAM3-RELATEDS_pombe_Mam3/Map4PANTHER

Orthologs

References / Literature

GO_REF:0000050 - Manual transfer of GO annotation data to genes by curator judgment of sequence model
PMID:23236291 - Deciphering the transcriptional-regulatory network of flocculation in Schizosaccharomyces pombe.
Kwon EJ et al. PLoS Genet 2012;8(12):e1003104
PMID:17870620 - Molecular phylogenetics of ascomycotal adhesins--a novel family of putative cell-surface adhesive proteins in fission yeasts.
Linder T et al. Fungal Genet Biol 2008 Apr;45(4):485-97
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:23163955 - Analysis of stress-induced duplex destabilization (SIDD) properties of replication origins, genes and intergenes in the fission yeast, Schizosaccharomyces pombe.
Yadav MP et al. BMC Res Notes 2012 Nov 19;5:643
PMID:26896847 - Ensembl comparative genomics resources.
Herrero J et al. Database (Oxford) 2016;2016
PMID:27886462 - Loss of ppr3, ppr4, ppr6, or ppr10 perturbs iron homeostasis and leads to apoptotic cell death in Schizosaccharomyces pombe.
Su Y et al. FEBS J 2017 Jan;284(2):324-337
PMID:36408920 - UniProt: the Universal Protein Knowledgebase in 2023.
UniProt Consortium Nucleic Acids Res 2023 Jan 06;51(D1):D523-D531
PMID:37787768 - Broad functional profiling of fission yeast proteins using phenomics and machine learning.
Rodríguez-López M et al. Elife 2023 Oct 03;12
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83