protein coding gene - mrp7 (SPAP19A11.05c) - mitochondrial ribosomal protein subunit L27

Gene summary

Standard name: mrp7
Systematic ID: SPAP19A11.05c
Product: mitochondrial ribosomal protein subunit L27
Organism: Schizosaccharomyces pombe (fission yeast)
Synonyms: SPBP19A11.05c
UniProt ID: Q9HDV5
ORFeome ID: 41/41C04
Characterisation status: biological role inferred
Feature type: mRNA gene
Genomic location: chromosome II: 2861479..2862760 reverse strand

Annotation

GO biological process

GO:0032543 - mitochondrial translation

References:

GO_REF:0000024

GO cellular component

GO:0005762 - mitochondrial large ribosomal subunit

References:

GO_REF:0000033

GO molecular function

GO:0003735 - structural constituent of ribosome

References:

GO_REF:0000033

Protein sequence feature

SO:0001808 - mitochondrial_targeting_signal

References:

PMID:36408920

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

PMID:23101633

Single locus phenotype

FYPO:0002111 - inviable tapered vegetative cell

References:

PMID:23697806

Genotypes:

mrp7delta

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

mrp7delta

FYPO:0002199 - inviable vegetative cell with normal cell morphology

References:

PMID:23697806

Genotypes:

mrp7delta

Taxonomic conservation

PBO:0011067 - conserved in bacteria

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Warnings

PBO:0004238 - systematic ID does not reflect chromosome

Protein features

ID	Name	InterPro name	DB name
PF01016	Ribosomal_L27	Ribosomal_bL27	PFAM
PS00831	RIBOSOMAL_L27	Ribosomal_bL27_CS	PROSITE_PATTERNS
PR00063	RIBOSOMALL27	Ribosomal_bL27	PRINTS
G3DSA:2.40.50.100:FF:000042			FUNFAM
SSF110324	Ribosomal L27 protein-like		SUPERFAMILY
G3DSA:2.40.50.100			GENE3D
PTHR15893	RIBOSOMAL PROTEIN L27	Ribosomal_bL27	PANTHER
mobidb-lite-Disorder	disorder_prediction		MOBIDB-Disorder
TIGR00062	L27	Ribosomal_bL27	NCBIFAM

Orthologs

MRPL27 (HGNC:14483) Homo sapiens
mrp7 (SJAG_03636) Schizosaccharomyces japonicus
MRP7 (YNL005C) Saccharomyces cerevisiae

References / Literature

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.: Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.: Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:21511999 - Comparative functional genomics of the fission yeasts.: Rhind N et al. Science 2011 May 20;332(6032):930-6
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).: Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:36408920 - UniProt: the Universal Protein Knowledgebase in 2023.: UniProt Consortium Nucleic Acids Res 2023 Jan 06;51(D1):D523-D531
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.: Hayles J et al. Open Biol 2013 May 22;3(5):130053
GO_REF:0000033 - Annotation inferences using phylogenetic trees