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tRNA gene - scn1 (SPATRNAALA.03) - tRNA Alanine

Gene summary

Standard name
scn1
Systematic ID
SPATRNAALA.03
Product
tRNA Alanine
Organism
Schizosaccharomyces pombe (fission yeast)
Feature type
tRNA gene
Genomic location
chromosome I: 3157430..3157501 forward strand

Annotation

GO biological process

GO:0002182 - cytoplasmic translational elongation

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GO cellular component

GO:0005737 - cytoplasm

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GO molecular function

GO:0033455 - GCA codon-amino acid adaptor activity

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Quantitative gene expression

PBO:0011963 - RNA level

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Single locus phenotype

FYPO:0000616 - abnormal mitotic anaphase progression

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Genotypes:

FYPO:0000080 - decreased cell population growth at low temperature

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Genotypes:

FYPO:0003268 - decreased rate of mitotic spindle elongation

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Genotypes:

FYPO:0000614 - increased duration of mitotic S phase

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Genotypes:

FYPO:0001490 - inviable elongated vegetative cell

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Genotypes:

FYPO:0002061 - inviable vegetative cell population

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Genotypes:

FYPO:0003166 - monoseptate vegetative cell with binucleate and anucleate compartments

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Genotypes:

FYPO:0001164 - normal growth on glucose carbon source

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Genotypes:

FYPO:0000764 - resistance to cycloheximide

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Genotypes:

FYPO:0000104 - sensitive to cycloheximide

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Genotypes:

FYPO:0000091 - sensitive to thiabendazole

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Genotypes:

FYPO:0000732 - short bipolar mitotic spindle

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Genotypes:

References / Literature

GO_REF:0000050 - Manual transfer of GO annotation data to genes by curator judgment of sequence model
PMID:15126629 - Suppression of a mitotic mutant by tRNA-Ala anticodon mutations that produce a dominant defect in late mitosis.
Kimata Y et al. J Cell Sci 2004 May 01;117(Pt 11):2283-93
PMID:7798319 - Bypassing anaphase by fission yeast cut9 mutation: requirement of cut9+ to initiate anaphase.
Samejima I et al. J Cell Biol 1994 Dec;127(6 Pt 1):1655-70
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.
Skribbe M et al. Mol Cell 2025 Feb 19;
GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference