protein coding gene - rpr2 (SPBC1105.16c) - RNase P subunit Rpr2

Gene summary

Standard name: rpr2
Systematic ID: SPBC1105.16c
Product: RNase P subunit Rpr2
Organism: Schizosaccharomyces pombe (fission yeast)
UniProt ID: Q9Y813
ORFeome ID: 01/01G04
Characterisation status: biological role inferred
Feature type: mRNA gene
Genomic location: chromosome II: 3537178..3538066 reverse strand

Annotation

GO biological process

GO:0008033 - tRNA processing

References:

GO_REF:0000033

GO cellular component

GO:0005829 - cytosol

References:

PMID:16823372

GO:0005655 - nucleolar ribonuclease P complex

References:

GO_REF:0000033

GO:0005634 - nucleus

References:

PMID:16823372

GO molecular function

GO:0004526 - ribonuclease P activity

References:

GO_REF:0000024

Quantitative gene expression

PBO:0011963 - RNA level

References:

PMID:23101633

Single locus phenotype

FYPO:0000951 - inviable small vegetative cell

References:

PMID:23697806

Genotypes:

rpr2delta

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

rpr2delta

Taxonomic conservation

PBO:0011072 - conserved in archaea

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

ID	Name	InterPro name	DB name
PF04032	Rpr2	Rpr2/Snm1/Rpp21	PFAM
G3DSA:6.20.50.20			GENE3D
PTHR14742	RIBONUCLEASE P SUBUNIT P21		PANTHER

Orthologs

RPP21 (HGNC:21300) Homo sapiens
rpr2 (SJAG_00306) Schizosaccharomyces japonicus
RPR2 (YIR015W) Saccharomyces cerevisiae

References / Literature

GO_REF:0000033 - Annotation inferences using phylogenetic trees
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.: Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.: Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:6262315 - Partial purification of RNase P from Schizosaccharomyces pombe.: Kline L et al. J Biol Chem 1981 May 25;256(10):5058-63
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.: Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.: Hayles J et al. Open Biol 2013 May 22;3(5):130053
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:21511999 - Comparative functional genomics of the fission yeasts.: Rhind N et al. Science 2011 May 20;332(6032):930-6