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protein coding gene - mrps28 (SPBC11B10.04c) - mitochondrial ribosomal protein subunit S15

Gene summary

Standard name
mrps28
Systematic ID
SPBC11B10.04c
Product
mitochondrial ribosomal protein subunit S15
Organism
Schizosaccharomyces pombe (fission yeast)
Synonyms
pi007, SPACTOKYO_453.29
UniProt ID
O13602
ORFeome ID
41/41G02
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome II: 1491579..1492925 reverse strand

Annotation

GO biological process

GO:0032543 - mitochondrial translation

References:

GO cellular component

GO:0005763 - mitochondrial small ribosomal subunit

References:

GO:0005739 - mitochondrion

References:

GO molecular function

GO:0003723 - RNA binding

References:

GO:0003735 - structural constituent of ribosome

References:

Protein sequence feature

SO:0001808 - mitochondrial_targeting_signal

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0002111 - inviable tapered vegetative cell

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

Taxonomic conservation

PBO:0011067 - conserved in bacteria

PBO:0011065 - conserved in eukaryotes

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

IDNameInterPro nameDB name
PF00312Ribosomal_S15Ribosomal_uS15Pfam
cd00353Ribosomal_S15p_S13eRibosomal_uS15CDD
SM01387Ribosomal_S15Ribosomal_uS15SMART
G3DSA:1.10.287.10CATH-Gene3D
SSF47060uS15_NS1_RNA-bd_sfSUPERFAMILY
PTHR23321Ribosomal_uS15_bactPANTHER
TIGR00952S15_bactRibosomal_uS15_bactNCBIFAM
CoilCOILS
MF_01343_BRibosomal_uS15_BRibosomal_uS15_bactHAMAP

Orthologs

References / Literature

PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:36408920 - UniProt: the Universal Protein Knowledgebase in 2023.
UniProt Consortium Nucleic Acids Res 2023 Jan 06;51(D1):D523-D531
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:16823372 - ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe.
Matsuyama A et al. Nat Biotechnol 2006 Jul;24(7):841-7
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
PMID:34119521 - Schizosaccharomyces pombe Ppr10 and Mpa1 together mediate mitochondrial translational initiation.
Luo Y et al. J Biol Chem 2021 Jul;297(1):100869
PMID:30321377 - Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome.
Telekawa C et al. Nucleic Acids Res 2018 Nov 30;46(21):11169-11183
PMID:30824696 - Systematic analysis reveals the prevalence and principles of bypassable gene essentiality.
Li J et al. Nat Commun 2019 Mar 01;10(1):1002
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6