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protein coding gene - trs20 (SPBC11G11.04) - TRAPP I, II and III complex subunit Trs20

Gene summary

Standard name
trs20
Systematic ID
SPBC11G11.04
Product
TRAPP I, II and III complex subunit Trs20
Organism
Schizosaccharomyces pombe (fission yeast)
UniProt ID
Q9USZ5
ORFeome ID
06/06D05
Characterisation status
biological role inferred
Feature type
mRNA gene
Genomic location
chromosome II: 1762423..1763290 forward strand

Annotation

Disease association

MONDO:0008471 - spondyloepiphyseal dysplasia congenita

References:

MONDO:0010737 - spondyloepiphyseal dysplasia tarda, X-linked

References:

GO biological process

GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport

References:

GO:0006891 - intra-Golgi vesicle-mediated transport

References:

GO:0016236 - macroautophagy

References:

GO cellular component

GO:0005801 - cis-Golgi network

References:

GO:0005829 - cytosol

References:

GO:1990070 - TRAPPI protein complex

References:

GO:1990071 - TRAPPII protein complex

References:

GO:1990072 - TRAPPIII protein complex

References:

Quantitative gene expression

PBO:0006310 - protein level

References:

PBO:0011963 - RNA level

References:

Single locus phenotype

FYPO:0001042 - inviable after spore germination, single or double cell division

References:

Genotypes:

FYPO:0000310 - inviable after spore germination, without cell division, with normal germ tube morphology

References:

Genotypes:

FYPO:0002151 - inviable spore

References:

Genotypes:

FYPO:0002061 - inviable vegetative cell population

References:

Genotypes:

Taxonomic conservation

PBO:0011065 - conserved in eukaryotes

PBO:0011071 - conserved in eukaryotes only

PBO:0011064 - conserved in fungi

PBO:0011069 - conserved in metazoa

PBO:0011070 - conserved in vertebrates

PBO:0006222 - predominantly single copy (one to one)

Protein features

IDNameInterPro nameDB name
PF04628Sedlin_NSedlinPfam
cd14825TRAPPC2_sedlinCDD
SM01399SybindinTRAPPCSMART
G3DSA:3.30.450.70:FF:000001CATH-FunFam
G3DSA:3.30.450.70CATH-Gene3D
SSF64356Longin-like_dom_sfSUPERFAMILY
PTHR12403SedlinPANTHER

Orthologs

References / Literature

PMID:21511999 - Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6
PMID:23101633 - Quantitative analysis of fission yeast transcriptomes and proteomes in proliferating and quiescent cells.
Marguerat S et al. Cell 2012 Oct 26;151(3):671-83
PB_REF:0000003 - Disease Association Curation
GO_REF:0000111 - Gene Ontology annotations Inferred by Curator (IC) using at least one Inferred by Sequence Similarity (ISS) annotation to support the inference
PMID:31474649 - Identification of 15 New Bypassable Essential Genes of Fission Yeast.
Takeda A et al. Cell Struct Funct 2019 Sep 27;44(2):113-119
PB_REF:0000006 - Disease associations from Monarch via human-pombe orthologs
PMID:20473289 - Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe.
Kim DU et al. Nat Biotechnol 2010 Jun;28(6):617-623
PMID:24763107 - Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).
Carpy A et al. Mol Cell Proteomics 2014 Aug;13(8):1925-36
GO_REF:0000108 - Automatic assignment of GO terms using logical inference, based on on inter-ontology links.
PMID:23697806 - A genome-wide resource of cell cycle and cell shape genes of fission yeast.
Hayles J et al. Open Biol 2013 May 22;3(5):130053
GO_REF:0000024 - Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity.
PMID:26771498 - A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human.
Vo TV et al. Cell 2016 Jan 14;164(1-2):310-323
PMID:40015273 - A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin.
Skribbe M et al. Mol Cell 2025 Feb 19;
PMID:24713849 - Post-transcriptional regulation of meiotic genes by a nuclear RNA silencing complex.
Egan ED et al. RNA 2014 Jun;20(6):867-81